The development of a multi-nitroimidazole residue analysis assay by optical biosensor via a proof of concept project to develop and assess a prototype test kit

An assay based on optical biosensor technology has been developed to detect a broad range of nitroimidazole drug residues and their metabolites (dimetridazole (DMZ), metronidazole (MNZ), ronidazole (RNZ), hydroxymetronidazole (HO-MNZ) and hydroxydimetridazole (HO-DMZ)) in chicken muscle. The detection limit for the procedure was determined as 0.5 ppb for DMZ and detection capabilities (CCβs) ranged from <1 ppb for DMZ, MNZ and RNZ to <2 ppb for HO-MNZ and HO-DMZ. Intra-assay variation (n = 6) was calculated as 11.6% at a concentration of 1 ppb DMZ and 4.7% at a concentration of 2 ppb DMZ. Inter-assay variation (n = 3) was determined to be 14.2% at a concentration of 1 ppb DMZ and 3.5% at a concentration of 2 ppb DMZ.A prototype kit based on this assay was produced and a multinational study was undertaken to independently evaluate its performance. The resulting data showed that the kit can be implemented with little difficulty in laboratories of varying expertise and is sensitive enough to meet the standards required by international law. Feedback from this study led to the incorporation of some minor improvements to the kit. The commercial partner in the project, XenoSense Ltd., was consulted with regards to producing a commercial test kit based on the prototype assay. As feedback from the collaborative study had been positive with respect to speed, ease of use and performance of the kit, the decision to commercialise the kit was taken. In conclusion, the prototype nitroimidazole kit was shown to offer numerous advantages over existing analytical techniques.     

基于IPv6的大规模接入汇聚路由器的设想和实现

针对下一代互联网面临的新业务拓展和安全性服务问题,本文综述了对未来网络的可运营、可管理和可控制的综合要求,提出了基于IPv6的大规模接入汇聚路由器(converging router access,ACR)的新概念,并分析了ACR工程实现的若干关键问题.ACR的提出不仅打破了大容量高性能路由器仅在核心骨干网络中使用的传统观念,开辟了大容量高性能路由器新的应用环境,而且为在下一代互联网中开展大规模、高速稳定和安全可靠的宽窄带新业务提供了创新的技术途径.     

基于ACR的多屏同步互动应用技术浅析

近年来,以家庭融合网络和智能终端为载体,联通网络虚拟社会和现实生活环境,面向家庭提供文化娱乐、生活消费、社区公益等综合服务的数字家庭服务形态成为了焦点。本文重点分析了数字家庭服务中的多屏同步互动应用技术,包括系统总体架构,基于云的平台架构,音频水印、视频水印、音频指纹、视频指纹四种ACR技术以及相关应用业务,并对多屏同步互动应用的趋势和发展进行了探讨,为日后基于自动内容识别技术的多屏同步互动应用实现与改进提供了参考。     

不同结构的ACR核壳粒子增韧聚碳酸酯的机理

用自制的核壳结构丙烯酸酯类共聚物(ACR)与聚碳酸酯(PC)共混制成共混材料(PC-ACR),考察了ACR的粒径以及ACR的壳层引入甲基丙烯酸缩水甘油酯(GMA)单体后对PC-ACR共混物冲击强度的影响.壳层引入GMA的ACR提高PC缺口韧性的效果并不明显;而ACR的粒径对PC-ACR冲击韧性的影响较大.运用J积分断裂韧性分析比较了ACR粒径对共混物断裂过程中弹性形变区-塑性形变区能量吸收能力的影响.塑性形变作为主要能量吸收途径在提高共混物韧性方面起主要作用,粒径为177.5 nm的ACR提高PC的断裂韧性效果最好,与悬臂梁冲击实验得到的冲击强度数据一致.     

铜缆在数据高速传输中的应用及发展

本文就铜缆在数据高速传输领域中的应用及其现状和今后的发展方向作了简要介绍，并重点讨论了几个目前较有争议的问题。