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11.
12.
W. Russ Algar 《Analytica chimica acta》2010,673(1):1-25
A comprehensive review of the development of assays, bioprobes, and biosensors using quantum dots (QDs) as integrated components is presented. In contrast to a QD that is selectively introduced as a label, an integrated QD is one that is present in a system throughout a bioanalysis, and simultaneously has a role in transduction and as a scaffold for biorecognition. Through a diverse array of coatings and bioconjugation strategies, it is possible to use QDs as a scaffold for biorecognition events. The modulation of QD luminescence provides the opportunity for the transduction of these events via fluorescence resonance energy transfer (FRET), bioluminescence resonance energy transfer (BRET), charge transfer quenching, and electrochemiluminescence (ECL). An overview of the basic concepts and principles underlying the use of QDs with each of these transduction methods is provided, along with many examples of their application in biological sensing. The latter include: the detection of small molecules using enzyme-linked methods, or using aptamers as affinity probes; the detection of proteins via immunoassays or aptamers; nucleic acid hybridization assays; and assays for protease or nuclease activity. Strategies for multiplexed detection are highlighted among these examples. Although the majority of developments to date have been in vitro, QD-based methods for ex vivo biological sensing are emerging. Some special attention is given to the development of solid-phase assays, which offer certain advantages over their solution-phase counterparts. 相似文献
13.
In this work, we used time-sliced ion velocity imaging to study the photodissociation dynamics of MgO at \mbox{193 nm}. Three dissociation pathways are found through the speed and angular distributions of magnesium. One pathway is the one-photon excitation of MgO(X\begin{document}$^1\Sigma^+$\end{document} ) to MgO(G\begin{document}$^1\Pi$\end{document} ) followed by spin-orbit coupling between the G\begin{document}$^1\Pi$\end{document} , 3\begin{document}$^3\Pi$\end{document} and 1\begin{document}$^5\Pi$\end{document} states, and finally dissociated to the Mg(\begin{document}$^3$\end{document} P\begin{document}$_\textrm{u}$\end{document} )+O(\begin{document}$^3$\end{document} P\begin{document}$_\textrm{g}$\end{document} ) along the 1\begin{document}$^5\Pi$\end{document} surface. The other two pathways are one-photon absorption of MgO(A\begin{document}$^1\Pi$\end{document} ) state to MgO(G\begin{document}$^1\Pi$\end{document} ) and MgO(4\begin{document}$^1\Pi$\end{document} ) state to dissociate into Mg(\begin{document}$^3$\end{document} P\begin{document}$_\textrm{u}$\end{document} )+O(\begin{document}$^3$\end{document} P\begin{document}$_\textrm{g}$\end{document} ) and Mg(\begin{document}$^1$\end{document} S\begin{document}$_\textrm{g}$\end{document} )+O(\begin{document}$^1$\end{document} S\begin{document}$_\textrm{g}$\end{document} ), respectively. The anisotropy parameters of the dissociation pathways are related to the lifetime of the vibrational energy levels and the coupling of rotational and vibronic spin-orbit states. The total kinetic energy analysis gives \begin{document}$D_0$\end{document} (Mg\begin{document}$-$\end{document} O)=21645\begin{document}$\pm$\end{document} 50 cm\begin{document}$^{-1}$\end{document} . 相似文献
14.
193 nm ArF浸没式光刻技术PK EUV光刻技术 总被引:1,自引:1,他引:0
翁寿松 《电子工业专用设备》2007,36(4):17-18
2006年11月英特尔决定采用193nm ArF浸没式光刻技术研发32nm工艺。2007年2月IBM决定在22nm节点上抛弃EUV光刻技术,采用193nm ArF浸没式光刻技术。对于32nm/22nm工艺,193nm ArF浸没式光刻技术优于EUV光刻技术,并将成为主流光刻技术。 相似文献
15.
633 nm激光辐射沿心包经脉线传输特性的实验测量 总被引:1,自引:0,他引:1
基于生物医学光学的原理与测量技术,设计了无损检测光波沿人体经脉线传输特性的实验方案,测量了633 nm光波沿心包经脉线和旁开非经脉线方向的光波辐出度特征,分析了光波调制频率对测量光信号的影响.实验对象为20例健康青年志愿者,实验结果采用医学统计软件SPSS13.0进行统计分析.研究初步表明:光波沿经脉线方向和非经脉线方向的光强度衰减差异明显(P<0.01),且光波沿经脉线方向的衰减小于非经脉线方向;在低频范围内,光波调制频率越大,光波沿经脉线的衰减越快. 相似文献
16.
本文以对氯苯酚(4-CP)、对硝基苯酚(4-NP)和罗丹明B(Rh B)为模型有机物(以4-CP和4-NP为小分子模型有机物,以Rh B为大分子模型有机物),分别研究了185 nm UV对水中这3种模型有机物的降解规律、性能和效果.研究结果表明,185 nm UV直接对水中4-CP、4-NP和Rh B有很好的降解效果.研究内容包括:185 nm UV降解模型有机物的浓度、TOC(Total organic carbon)浓度、185 nm UV降解模型有机物过程中溶液pH及电导率变化、以及降解模型有机物过程中产生的无机离子等几个方面. 相似文献
17.
1550nm技术的不断进步,光设备的不断成熟和商用化。推动了数字电视整体平移和快速发展。本文介绍了遵义市从2003年开始建设数字电视传输自愈环,在探索中创新,不断优化技术方案,确保高质量既经济又安全的传输。 相似文献
18.
Huang Lingxiong Zhang Ge Huang Chenghui Wei Yong Zhu Haiyong 《Journal of Russian Laser Research》2008,29(6):593-598
We develop a separate 1319 and 1338 nm Nd:YAG laser system with a blazing grating (600 lines/mm). The resonator of this system
has a Littrow grating configuration and a highly reflective mirror, in which the zero-order diffraction of the grating acts
as the laser output. By virtue of the wavelength-dependent reflectivity of the grating, a single-wavelength laser at 1319
nm or 1338 nm can be realized. In view of the laser rate equations and using the distribution of the blazing grating, we analyze
the oscillation conditions providing single-wavelength laser operation in the system. 相似文献
19.
20.
Duan Yan-min Li Ai-hong Chen Jing Zhu Hai-yong Zhang Ge Huang Cheng-hui Wei Yong Huang Ling-xiong Qiu Yi-shen 《Journal of Russian Laser Research》2008,29(3):268-273
We report an LD-end-pumped linearly-polarized continuous-wave (CW) Nd:YAP laser operating at 1341.4 nm. Making use of the
plane-concave resonator (T = 2.4%) and the plane-plane resonator (T = 2.6%), we obtain linearly-polarized laser radiation at 1341.4 nm with a power of 3.15 and 2.86 W and corresponding optical
slope efficiency of 18.4 and 17.5%, respectively. The effect of the laser oscillation mode on the output is analyzed. An experiment
on the intra-cavity frequency doubling with an LBO crystal has been performed, and a laser power of 431 mW in one direction
at 670.7 nm was obtained. 相似文献