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91.
Preparation of polyarylester dendrimers containing 2-(hydroxymethyl)-1,4-butanediol and 2,2-bis(hydroxymethyl)-1,4-butanediol cores is described. These polyarylester dendrimers are unsymmetrical with respect to chain lengths and function as model systems for studying in vitro controlled drug release systems. Reaction conditions for deprotection of trichloroethyl group of the dendritic wedges have been improved. 相似文献
92.
We study the motion of isentropic gas in nozzles. This is a major subject in fluid dynamics. In fact, the nozzle is utilized to increase the thrust of rocket engines. Moreover, the nozzle flow is closely related to astrophysics. These phenomena are governed by the compressible Euler equations, which are one of crucial equations in inhomogeneous conservation laws.In this paper, we consider its unsteady flow and devote to proving the global existence and stability of solutions to the Cauchy problem for the general nozzle. The theorem has been proved in Tsuge (2013). However, this result is limited to small data. Our aim in the present paper is to remove this restriction, that is, we consider large data. Although the subject is important in Mathematics, Physics and engineering, it remained open for a long time. The problem seems to rely on a bounded estimate of approximate solutions, because we have only method to investigate the behavior with respect to the time variable. To solve this, we first introduce a generalized invariant region. Compared with the existing ones, its upper and lower bounds are extended constants to functions of the space variable. However, we cannot apply the new invariant region to the traditional difference method. Therefore, we invent the modified Godunov scheme. The approximate solutions consist of some functions corresponding to the upper and lower bounds of the invariant regions. These methods enable us to investigate the behavior of approximate solutions with respect to the space variable. The ideas are also applicable to other nonlinear problems involving similar difficulties. 相似文献
93.
The cross injection in a supersonic flow is an issue encountered in several aerodynamic applications such as fuel injection in scramjet combustor, missile control, drag reduction and thrust vector control. In a recent work, an analytical model has been presented to calculate the fluidic thrust vectoring performance for a supersonic axisymmetric nozzle. The model is able to take into account both the injected gas thermodynamic properties and the geometrical nozzle characteristics. The analytical model has been successfully validated following the cold air flow experimental analysis, in the case of fluidic thrust vectoring applied to conical nozzle. The aim of this work is to show how far the injected gas thermodynamic properties, different from that of the nozzle main flow, could influence the fluidic thrust vectorization parameters.In this work, the experimental performance of the fluidic thrust vectoring concept, using numbers of gases as injectant, has been qualitatively and quantitatively analyzed. Schlieren visualization, force balance and wall pressure measurements were used in the case of a truncated ideal contour nozzle. The experimental results are compared to the numerical and analytical findings.Performance analysis are conducted and basic conclusions are drawn in terms of thermodynamic gas properties effect on the fluidic thrust vector system. The primary effect was related to the gas molecular weight and its specific heat ratio product. It is observed that for fixed injection conditions, the vectoring angle is higher when the injected gas molecular weight and specific heat ratio product is less than that of the primary gas. For a given mission of the launcher, it can be concluded that the mass of the embedded gas, used for the fluidic vectorization system, can be significantly reduced, depending on its molecular weight and specific heat ratio. 相似文献
94.
《Wave Motion》2015
It is pointed out some inaccuracies in Idemen’s method [Idemen (2000, 2011)] while having investigated electromagnetic field near the edge of a resistive half-plane. The limiting for the field expansion only to the first power of logarithmic function is not valid and rigorously leads to the trivial solution. It is needed to include the logarithmic functions to the field expansion in any cases when among the solutions of the characteristic equation there are roots that differ from one another by any integer. 相似文献
95.
Investigations of gas and particle dynamics in first generation needle-free drug delivery devices 总被引:1,自引:0,他引:1
Abstract. Transdermal powdered drug delivery involves the propulsion of solid drug particles into the skin by means of high-speed gas-particle
flow. The fluid dynamics of this technology have been investigated in devices consisting of a convergent-divergent nozzle
located downstream of a bursting membrane, which serves both to initiate gas flow (functioning as the diaphragm of a shock
tube) and to retain the drug particles before actuation. Pressure surveys of flow in devices with contoured nozzles of relatively
low exit-to-throat area ratio and a conical nozzle of higher area ratio have indicated a starting process of approximately
200 s typical duration, followed by a quasi-steady supersonic flow. The velocity of drug particles exiting the contoured nozzles
was measured at up to 1050 m/s, indicating that particle acceleration took place primarily in the quasi-steady flow. In the
conical nozzle, which had larger exit area ratio, the quasi-steady nozzle flow was found to be overexpanded, resulting in
a shock system within the nozzle. Particles were typically delivered by these nozzles at 400 m/s, suggesting that the starting
process and the quasi-steady shock processed flow are both responsible for acceleration of the particle payload. The larger
exit area of the conical nozzle tested enables drug delivery over a larger target disc, which may be advantageous.
Received 12 March 2000 / Accepted 8 June 2000 相似文献
96.
A spray cooling heat transfer experiment on straight fin surface under acceleration conditions was conducted to investigate the effects of acceleration, flow rate, and nozzle height. The results show that the acceleration can improve the heat transfer performance in a limited way. In addition, whether in the acceleration or stationary condition, the flow rate as well as the nozzle height has the same impact on the spray cooling performance. It is also observed that the surface temperature can influence the effect of flow rate on spray cooling performance, and the cooling performance becomes worse with the increase of nozzle height. 相似文献
97.
Noise reduction in a vacuum cleaner with a brush nozzle for cleaning a bed blanket is investigated numerically in fluid dynamic aspects. Governing equations describing nonlinear flow fields in a suction nozzle are solved simultaneously. The components of a rotary fan, a brush drum, and a separation block are installed in the nozzle. First, flow patterns in the nozzle are analyzed and based on them, flow resistance is evaluated to find a primary noise source. Flow resistance induces the loss of a suction performance as well as noise generation. In the brush nozzle, the separation block and the rotary fan obstruct smooth air flow and result in high level of noise emission. The rotation of the fan itself affects little noise generation. From the numerical results, a method to reduce noise and maintain the suction performance is suggested. In this method, the suction performance is increased through the optimization of the separation block, which is attained by the modification of its shape. And then, the height of a fan blade is shortened, leading to the performance loss. At the cost of it, the sound power level of noise is reduced by 4-5 dB(A) and at the same time, the tonal noise and the sound quality are improved appreciably. The method has been verified by experimental tests. It is found that in the brush nozzle, flow resistance is critical in noise emission and accordingly, fluid dynamic approach to noise reduction is effective. 相似文献
98.
Yusuf Z. Umul 《Optics & Laser Technology》2010,42(1):32-36
The scattering of plane waves by a black wedge is examined. Two methods are considered for the solution of the problem. A closed-form series solution is derived by performing the technique of the separation of variables using boundary conditions of Macdonald. The second approach is the method of the modified theory of physical optics. The results are compared numerically. 相似文献
99.
《Wave Motion》2020
In this work we study diffraction of a spherical acoustic wave due to a point source, by an impedance wedge In the exterior of the wedge the acoustic pressure satisfies the stationary wave (Helmholtz) equation and classical impedance boundary conditions on two faces of the wedge, as well as Meixner’s condition at the edge and the radiation conditions at infinity. Solution of the boundary value problem is represented by a Weyl type integral and its asymptotic behavior is discussed. On this way, we derive various components in the far field interpreting them accordingly and discussing their physical meaning. 相似文献
100.
A twin-fluid nozzle was proposed for low-pressure atomization. The nozzle is featured by swirling air flows in the mixing chamber. Liquid medium is thereby inhaled due to the pressure difference. An experimental work was performed to investigate the atomization performance of the nozzle and the hydrogen peroxide solution served as the liquid medium. Droplet size and droplet velocity were measured. Effects of the diameter of the air-injection orifice and the air-injection pressure were investigated. The results show that small droplet size is achieved with the proposed nozzle. As the spray develops, Sauter mean diameter (SMD) of the droplets decreases first and then increases, irrespective of the variation of the air-injection orifice diameter and the air-injection pressure. Overall SMD varies inversely with the air-injection orifice diameter and air-injection pressure. Near the nozzle, cross-sectional velocity distribution exhibits a peak-valley pattern, which is replaced with uniformized velocity distributions away from the nozzle. Similarity of cross-sectional radial velocity distribution at different air pressures is evidenced. Furthermore, the correlation between droplet size and droplet velocity is established. 相似文献