PVCM, PVCD, EPL, and irritable larynx syndrome: What are we talking about and how do we treat it?

Paroxysmal vocal cord movement/motion (PVCM), paroxysmal vocal cord dysfunction (PVCD), episodic paroxysmal laryngospasm (EPL), and irritable larynx syndrome (ILS) are terms used to describe laryngeal dysfunction masquerading as asthma, upper airway obstruction, or functional and organic voice disorders. The differential diagnosis of PVCM, PVCD, EPL, and ILS is critical to successful medical and behavioral management of the patient. During the past 10 years, 27 subjects, ages 15–79 years, were identified to have paroxysms of inspiratory stridor, acute respiratory distress, associated aphonia and dysphonia, resulting in misdiagnosis and unnecessary emergency treatments, including endotracheal intubation, cardiopulmonary resuscitation, massive pharmacotherapy, or tracheostomy. A multifactorial management program is proposed utilizing principles of motor learning, neurolinguistic programming model, respiratory and phonatory synchronization, relaxation techniques, concurrent monitoring of behavioral adjustments, and formal psychological counseling.     

非圆化磨耗激励下高速列车转向架区域噪声边频带产生机理及影响

该文通过对车辆噪声和车轮非圆化磨耗开展跟踪测试和分析,发现存在车轮非圆化磨耗的列车在运行过程中,其转向架区域噪声窄带频谱上会出现了以非圆化磨耗激励频率为中心,以过轨枕频率为间隔等间距分布的噪声峰值(即噪声边频带).这使得车轮非圆化磨耗不仅会影响其激励频率处的列车轨道结构的振动和噪声,还会对其他频段的噪声产生重要影响.为...     

Team-moving effect in bi-direction pedestrian flow

We propose a cellular automation model to simulate team-moving behavior in bi-directional pedestrian flow. The moving rules for double-pedestrian teaming include the constraint that pedestrians remain on adjacent cells. Phase transition, critical density — team number, velocity–density, and flow–density relationships are key component parts of the analysis. Simulations show that team-moving produces significant corridor capacity effects, and effects highly depend on the type of teaming behavior. In daily life, pedestrians prefer traverse teaming; under this bias, as teaming pedestrians increase in number, critical density reduces; that means traverse teaming will weaken the capacity of the corridor. The effect of traverse team-moving is nonlinear, and capacity will continually reduce as the team numbers increase; however, reduction rate will decay. We call this phenomenon, “the marginal utility of team-moving.”     

脉冲序列控制电流断续模式Buck变换器的动力学建模与边界碰撞分岔

通过建立一个开关周期内输出电容电荷变化量对应的输出电压变化量, 建立了工作于电感电流断续模式(discontinuous conduction mode, DCM)的脉冲序列(pulse train, PT)控制Buck变换器的近似离散时间模型, 研究了负载电阻及输入电压变化时PT控制DCM Buck变换器的边界碰撞分岔行为. 通过构造相应的迭代映射曲线, 分别分析了不同负载电阻时PT控制DCM Buck变换器的周期1、周期2和周期3运行轨迹的不动点稳定性, 揭示了PT控制DCM Buck变换器在不同周期态时的边界碰撞分岔的形成机理. 研究结果表明, 随参数变化, PT控制DCM Buck变换器始终运行在不同的周期态, 各周期态的切换由边界碰撞分岔引起, 李雅谱诺夫指数始终小于零. 利用PSIM电路仿真软件, 给出了不同负载电阻时的时域波形和相轨图. 实验结果验证了理论分析和仿真结果的正确性, 同时说明了本文动力学建模的可行性.     

多关节人体上肢运动的优化轨迹预测

研究了手端无约束条件下,多关节人体上肢点到点运动优化轨迹的预测. 首先建立了多关节上肢平面运动的动力学模型,根据最小功准则提出优化目标函数,将上肢点到点运动的优化轨迹求解问题转化为两点边值问题,设计了寻优的迭代算法,求得了上肢运动的优化轨迹与相应的速度变化曲线. 仿真结果表明: 平衡点位置或关节力矩平滑地变化,避免了肢体出现急加速-急减速的运动形式,减少了肢体运动时的能量消耗;手端的运动轨迹为近似直线,速度为单峰的钟形曲线,这与上肢优化运动的特征相吻合,也表明最小功准则可以有效预测多关节上肢运动的优化轨迹.      

岩层与地表移动的广义下沉公式

在考虑岩性差异的条件下,推导出了岩层与地表移动的广义下沉公式,最后列举了其应用意义和实例。     

一种固体转动演示测量仪

本文介绍了一种能直观演示固体转动的仪器 ,并介绍了转动惯量的测量方法     

蛋白质分子与配体结合过程构象变化的研究

蛋白质分子与配体的作用模式主要有直接的环区结合及铰链式结合两种方式。针对这两种不同的作用方式,我们提出采用不同的策略进行结合过程的构象研究。对于直接的环区结合模式,通过建立环区主链构象库,来实现蛋白质环区与配体的准柔性对接,并以链霉抗生物素蛋白体系为例对构象库建立的可行性进行了验证计算。对铰链结合方式,采用分步对接的方法进行计算,并具体应用于HIV蛋白酶与其小分子配体的结合过程。计算结果表明,这两种处理方法分别能较好地模拟不同类型的蛋白质与配体结合的的构象变化。     

晶型转变对尼龙11分子链运动的影响

Two crystal forms (α and δ′ form) of nylon 11 were prepared by melting, ice water bath quenching and annealing. The characteristic of chain movement of two forms was investigated using dielectric relaxation spectroscopy in the frequency range from 42 Hz to 5 MHz. The dielectric temperature spectra at different frequencies show that the primary α relaxation corresponding to the chain segment movement is located at higher temperature in α form, indicating the chain segment movement is restricted after δ′→α crystal transition. The activation energy of secondary β relaxation remained almost unchanged for two forms, but the relaxation time was longer and the relaxation strength was weaker for α form, confirming that the local relaxation was also restricted to some extent after δ′→α crystal transition.     

三色圆偏振激光组合脉冲驱动氦原子产生椭圆偏振的阿秒脉冲

我们提出利用频率为ω,3ω和强度较弱的2ω组成的三色圆偏振激光组合脉冲驱动氦原子能够得到椭偏率较大的阿秒脉冲链的一种方法.通过强场近似方法,计算了氦原子在两色和三色圆偏振激光组合脉冲驱动下发射高次谐波谱及其合成阿秒脉冲链,比较了氦原子(初态为s态)在这两种情况下发射高次谐波谱的特点及其合成阿秒脉冲链椭偏率的大小,结果发现,在反旋的两色ω,3ω激光脉冲基础上加入了频率为2ω的第三色激光脉冲联合作用到氦原子上,所得到的阿秒脉冲链的椭偏率相对于双圆场情况下有所增加,通过调整ω,3ω激光的强度比,并且选择适当的第三色激光的强度,对初态为s态的原子,仍能够得到具有较大椭偏率的阿秒脉冲链.