Three-dimensional flow of Powell–Eyring nanofluid with heat and mass flux boundary conditions

This article investigates the three-dimensional flow of Powell–Eyring nanofluid with thermophoresis and Brownian motion effects. The energy equation is considered in the presence of thermal radiation. The heat and mass flux conditions are taken into account. Mathematical formulation is carried out through the boundary layer approach. The governing partial differential equations are transformed into the nonlinear ordinary differential equations through suitable variables. The resulting nonlinear ordinary differential equations have been solved for the series solutions. Effects of emerging physical parameters on the temperature and nanoparticles concentration are plotted and discussed. Numerical values of local Nusselt and Sherwood numbers are computed and examined.     

Parasitic effects of air-gap through-silicon vias in high-speed three-dimensional integrated circuits

In this paper,ground-signal-ground type through-silicon vias(TSVs) exploiting air gaps as insulation layers are designed,analyzed and simulated for applications in millimeter wave.The compact wideband equivalent-circuit model and passive elements(RLGC) parameters based on the physical parameters are presented with the frequency up to 100 GHz.The parasitic capacitance of TSVs can be approximated as the dielectric capacitance of air gaps when the thickness of air gaps is greater than 0.75 μm.Therefore,the applied voltage of TSVs only needs to achieve the flatband voltage,and there is no need to indicate the threshold voltage.This is due to the small permittivity of air gaps.The proposed model shows good agreement with the simulation results of ADS and Ansoft's HFSS over a wide frequency range.     

In vitro three-dimensional cancer metastasis modeling:Past,present, and future

Metastasis is the leading cause of most cancer deaths, as opposed to dysregulated cell growth of the primary tumor.Molecular mechanisms of metastasis have been studied for decades and the findings have evolved our understanding of the progression of malignancy. However, most of the molecular mechanisms fail to address the causes of cancer and its evolutionary origin, demonstrating an inability to find a solution for complete cure of cancer. After being a neglected area of tumor biology for quite some time, recently several studies have focused on the impact of the tumor microenvironment on cancer growth. The importance of the tumor microenvironment is gradually gaining attention, particularly from the perspective of biophysics. In vitro three-dimensional(3-D) metastatic models are an indispensable platform for investigating the tumor microenvironment, as they mimic the in vivo tumor tissue. In 3-D metastatic in vitro models, static factors such as the mechanical properties, biochemical factors, as well as dynamic factors such as cell–cell, cell–ECM interactions, and fluid shear stress can be studied quantitatively. With increasing focus on basic cancer research and drug development, the in vitro 3-D models offer unique advantages in fundamental and clinical biomedical studies.     

Recent technical advancements enabled atomic resolution Cryo EM

With recent breakthroughs in camera and image processing technologies single-particle electron cryo-microscopy(CryoEM) has suddenly gained the attention of structural biologists as a powerful tool able to solve the atomic structures of biological complexes and assemblies. Compared with x-ray crystallography, Cryo EM can be applied to partially flexible structures in solution and without the necessity of crystallization, which is especially important for large complexes and assemblies. This review briefly explains several key bottlenecks for atomic resolution Cryo EM, and describes the corresponding solutions for these bottlenecks based on the recent technical advancements. The review also aims to provide an overview about the technical differences between its applications in biology and those in material science.     

Three-dimensional numerical simulation of crown spike due to coupling effect between bubbles and free surface

The motion of gas bubbles beneath a free surface will lead to a spike of fluid on the free surface. The distance of the bubbles to the free surface is the key factor to different phenomena. When the inception distance varies in some range, crown phenomenon would happen after the impact of weak buoyancy bubbles, so this kind of spike is defined as crown spike in the present paper. Based on potential flow theory, a three-dimensional numerical model is established to simulate the motion of the free-surface spike generated by one bubble or a horizontal line of two in-phase bubbles. After the downward jet formed near the end of the collapse phase, the simulation of the free surface is performed to study the crown spike without regard to the toroidal bubble＇s effect. Calculations about the interaction between one bubble and free surface agree well with the experimental results conducted with a high-speed camera, and relative error is within 15%. Crown spike in both single- and two-bubble cases are simulated numerically. Different features and laws of the motion of crown spike, depending on the bubble-boundary distances and the inter-bubble distances, have been investigated.     

Three-dimensional simulation method of multipactor in microwave components for high-power space application

Based on the particle-in-cell technology and the secondary electron emission theory, a three-dimensional simulation method for multipactor is presented in this paper. By combining the finite difference time domain method and the panicle tracing method, such an algorithm is self-consistent and accurate since the interaction between electromagnetic fields and particles is properly modeled. In the time domain aspect, the generation of multipactor can be easily visualized, which makes it possible to gain a deeper insight into the physical mechanism of this effect. In addition to the classic secondary electron emission model, the measured practical secondary electron yield is used, which increases the accuracy of the algorithm. In order to validate the method, the impedance transformer and ridge waveguide filter are studied. By analyzing the evolution of the secondaries obtained by our method, multipactor thresholds of these components are estimated, which show good agreement with the experimental results. Furthermore, the most sensitive positions where multipactor occurs are determined from the phase focusing phenomenon, which is very meaningful for multipactor analysis and design.     

嫦娥一号月面成像的高精度匹配及月貌三维重建

针对嫦娥一号探月卫星2C级月面成像,提出了基于待配点最优模板选择的二次函数形变补偿迭代匹配方法。仿真表明它能有效地适应地形起伏引起的图像形变,匹配精度较高且稳定性好。在标准相关匹配的基础上结合所提出的方法完成了下视图与前、后视图的精确匹配,采用三视约束机制和顺序检验机制保证了匹配的稳健性。分析了线阵相机成像的仿射近似模型,并以此为基础实现同轨三视重建。基于邻轨下视图同名特征点,采用RANSAC方法估计邻轨三维坐标转换参数,完成邻轨拼接。实验结果表明,三维重建的月貌图能够更好地表达月球表面的形状和地形。     

Three-dimensional vertical ZnO transistors with suspended top electrodes fabricated by focused ion beam technology

Three-dimensional(3D)vertical architecture transistors represent an important technological pursuit,which have distinct advantages in device integration density,operation speed,and power consumption.However,the fabrication processes of such 3D devices are complex,especially in the interconnection of electrodes.In this paper,we present a novel method which combines suspended electrodes and focused ion beam(FIB)technology to greatly simplify the electrodes interconnection in 3D devices.Based on this method,we fabricate 3D vertical core-double shell structure transistors with ZnO channel and Al₂O₃ gate-oxide both grown by atomic layer deposition.Suspended top electrodes of vertical architecture could be directly connected to planar electrodes by FIB deposited Pt nanowires,which avoid cumbersome steps in the traditional 3D structure fabrication technology.Both single pillar and arrays devices show well behaved transfer characteristics with an Ion/Ioff current ratio greater than 106 and a low threshold voltage around 0 V.The ON-current of the 2×2 pillars vertical channel transistor was 1.2μA at the gate voltage of 3 V and drain voltage of 2 V,which can be also improved by increasing the number of pillars.Our method for fabricating vertical architecture transistors can be promising for device applications with high integration density and low power consumption.     

Three-dimensional coupled-mode model and characteristics of low-frequency sound propagation in ocean waveguide with seamount topography

Large-scale topography, such as a seamount, substantially impacts low-frequency sound propagation in an ocean waveguide, limiting the application of low-frequency acoustic detecting techniques. A three-dimensional (3D) coupled-mode model is developed to calculate the acoustic field in an ocean waveguide with seamount topography and analyze the 3D effect. In this model, a correction is introduced in the bottom boundary, theoretically making the acoustic field satisfy the energy conservation. Furthermore, a large azimuth angle calculation range is obtained by using the operator theory and higher-order Padé approximation. Additionally, the model has advantages related to the coupling mode and parabolic equation theory. The couplings corresponding to the effects of range-dependent environment are fully considered, and the numerical implementation is kept feasible. After verifying the accuracy and reliability of the model, low-frequency sound propagation characteristics in the seamount environment are analyzed. The results indicate lateral variability in bathymetry can lead to out-of-plane effects such as the horizontal refraction phenomenon, while the coupling effect tends to restore the abnormal sound field and produces acoustic field diffraction behind the seamount. This model effectively considers the effects of the horizontal refraction and coupling, which are proportional to the scale of the seamount.