Diffusion properties of cortical and pericortical tissue: regional variations, reliability and methodological issues

Characterizing the diffusion properties of cortical tissue is complicated by intersubject variability in the relative locations of gyri and sulci. Here we extend methods of measuring the average diffusion properties of gyral and sulcal structures after they have been aligned to a common template of cortical surface anatomy. Diffusion tensor image (DTI) data were gathered from 82 young subjects and co-registered with high-resolution T1 images that had been inflated and co-registered to a hemispherically unified spherical coordinate system based on FreeSurfer. We analyzed fractional anisotropy (FA), mean diffusivity (MD) and the novel quantity of cortical primary diffusion direction (cPDD) at five surfaces parallel to the white/gray junction, spanning approximately 5 mm from the pial surface into white matter. FA increased with increasing depth, whereas MD and cPDD were reduced. There were highly significant and reliable regional differences in FA, MD and cPDD as well as systematic differences between cortical lobes and between the two hemispheres. The influence of nearby cortical spinal fluid (CSF), local cortical curvature and thickness, and sulcal depth was also investigated. We found that FA correlated significantly with cortical curvature and sulcal depth, while MD was strongly influenced by nearby CSF. The measurement of FA, MD and cPDD near the cortical surface clarifies the organization of fiber projections to and from the cortex.     

Minimum SNR and acquisition for bias-free estimation of fractional anisotropy in diffusion tensor imaging - a comparison of two analytical techniques and field strengths

Although it is known that low signal-to-noise ratio (SNR) can affect tensor metrics, few studies reporting disease or treatment effects on fractional anisotropy (FA) report SNR; the implicit assumption is that SNR is adequate. However, the level at which low SNR causes bias in FA may vary with tissue FA, field strength and analytical methodology. We determined the SNR thresholds at 1.5 T vs. 3 T in regions of white matter (WM) with different FA and compared FA derived using manual region-of-interest (ROI) analysis to tract-based spatial statistics (TBSS), an operator-independent whole-brain analysis tool. Using ROI analysis, SNR thresholds on our hardware-software magnetic resonance platforms were 25 at 1.5 T and 20 at 3 T in the callosal genu (CG), 40 at 1.5 and 3 T in the anterior corona radiata (ACR), and 50 at 1.5 T and 70 at 3 T in the putamen (PUT). Using TBSS, SNR thresholds were 20 at 1.5 T and 3 T in the CG, and 35 at 1.5 T and 40 at 3 T in the ACR. Below these thresholds, the mean FA increased logarithmically, and the standard deviations widened. Achieving bias-free SNR in the PUT required at least nine acquisitions at 1.5 T and six acquisitions at 3 T. In the CG and ACR, bias-free SNR was achieved with at least three acquisitions at 1.5 T and one acquisition at 3 T. Using diffusion tensor imaging (DTI) to study regions of low FA, e.g., basal ganglia, cerebral cortex, and WM in the abnormal brain, SNR should be documented. SNR thresholds below which FA is biased varied with the analytical technique, inherent tissue FA and field strength. Studies using DTI to study WM injury should document that bias-free SNR has been achieved in the region of the brain being studied as part of quality control.     

利用非线性传输线产生高功率射频场

根据孤立子理论,分析了利用变容非线性传输线产生射频场的机理。利用电路仿真方法系统地研究了影响射频场产生的相关参数,发现电感和零压电容越小、输入电压越大,射频场的频率越高;电容的非线性率越大,射频场的峰值电压越高、高频成分越多。并在此基础上,仿真设计了能产生峰值功率为0.8 GW、主频为19.42 MHz射频场的非线性传输线。     

基于InGaAs光谱成像技术的光纤光栅传感器在大坝渗流监测系统的应用

为了实现大坝渗流监测,提出了一种采用光谱成像技术的光纤Bragg光栅传感器和多点传感系统。基于室内实验结果,对监测系统可靠性与监测数据准确度进行和多点传感信号分辨因子分析,结果表明:用于坝体温度场检测的光线光栅传感器波长温度响应灵敏度可达0.009 1nm/℃;由光源带宽决定的测试系统可实现多个传感器的复用。实践表明:采用光纤光栅传感系统可进行大坝渗流自动监测,特别是在系统防雷击、抗干扰性方面,与传统仪器相比具有明显优势。     

基于高光谱成像的生鲜猪肉细菌总数预测建模方法研究

生鲜猪肉中细菌总数(TVC)超标会直接危害大众,为此研究验证高光谱成像技术结合相应的建模方法预测生鲜猪肉中TVC的可行性。针对非线性、小样本问题, 以及光谱维和空间维的大数据量问题,在综合比较偏最小二乘回归(PLSR)、人工神经网络(ANNs)和最小二乘支持向量机(LS-SVM)3种建模方法的基础上,最终选取了LS-SVM方法组建模型。3种建模方法综合比较的结果表明,LS-SVM同时兼顾了训练精度和泛化能力两方面的性能,使其都能做到最优,与标准平板菌落计数法所检测TVC的决定系数分别为0.987 2和0.942 6,校正均方根误差和预测标准均方根误差分别为0.207 1和0.217 6,其建模性能优于其他方法。研究结果表明,高光谱成像技术结合LS-SVM预测建模方法可作为快速、非破坏预测生鲜猪肉TVC的有效手段。     

Implementation of a novel two-attractor grid multi-scroll chaotic system

This paper proposed a method of generating two attractors in a novel grid multi-scroll chaotic system.Based on a newly generated three-dimensional system,a two-attractor grid multi-scroll attractor system can be generated by adding two triangular waves and a sign function.Some basic dynamical properties,such as equilibrium points,bifurcations,and phase diagrams,were studied.Furthermore,the system was experimentally confirmed by an electronic circuit.The circuit simulation results and numerical simulation results verified the feasibility of this method.     

Forward and inverse problem for cardiac magnetic field and electric potential using two boundary element methods

This paper discusses the forward and inverse problem for cardiac magnetic fields and electric potentials.A torso-heart model established by boundary element method(BEM) is used for studying the distributions of cardiac magnetic fields and electric potentials.Because node-to-node and triangle-to-triangle BEM can lead to discrepant field distributions,their properties and influences are compared.Then based on constructed torso-heart model and supposed current source functional model-current dipole array,the magnetic and electric imaging by optimal constrained linear inverse method are applied at the same time.Through figure and reconstructing parameter comparison,though the magnetic current dipole array imaging possesses better reconstructing effect,however node-to-node BEM and triangleto-triangle BEM make little difference to magnetic and electric imaging.     

惯性约束聚变的中子半影成像诊断系统的优化研究

在激光驱动的惯性约束聚变实验中,中子半影成像是重要的诊断方法.基于分辨率的要求,模拟了中子源与半影孔装置间不同距离、半影孔装置不同厚度、半影孔装置不同外径以及不同孔型的系统点扩展函数,通过分析点扩展函数的尖锐性和等晕性优化诊断系统.同时还给出了系统的装配误差要求,并发现系统在线性重建时能达到15 μm分辨率,而非线性重建时能满足5 μm分辨率的诊断要求. 关键词： 中子半影成像 Monte Carlo方法 系统优化 分辨率     

基于AD698的线性差动式位移传感器解码电路设计

线性差动式位移传感器(LVDT)由于其灵敏度高、线性度好、分辨率高、寿命长、可靠性高等优点,已广泛应用于机载测试系统中;为了设计出精度高,稳定性好,能够满足机载测试需求的LVDT传感器解码电路,分析了LVDT传感器磁芯位移与输出电压信号的关系,研究了AD698的内部解调原理,设计出了基于AD698的信号解码电路;该电路通过外围元器件产生传感器所需的激励信号,并对激励信号和传感器输出信号进行解调得到与传感器磁芯位移成正比的直流电压;最后通过实验验证该电路具有结构简单、稳定性高、精度高的优点,能够满足机载测试的要求,且该电路已经过高低温和振动试验,并成功应用于机载测试采集系统中。     

电子式互感器高频数据采集与传输方案

针对当前电力系统电子式互感器采样率偏低,难以满足行波测距装置准确定位电力故障的问题,提出了电子式互感器高频信号采集与传输方案;电子式互感器内部为Rogowski 线圈,电网电流信号被其微分作用转换为小电压信号并附加了90°超前相差,设计积分电路补偿该相差;设计采样率为2 MSps的高频信号采集电路,FPGA通过LVDS接口读取采样数据,并进行幅值处理,最后利用大容量FIFO(先入先出单元)进行缓存;由于百兆网数据传输速率有限,利用FPGA设计吉比特光纤以太网传输特定格式报文,把电流数据传输至电力行波测距装置;解决了积分电路由于运放输入偏置电压带来的积分饱和问题,以及高速ADC输入量程小于输入信号幅值等技术难点;试验结果表明,高频信号采集及传输方案能够满足行波测距装置百米级别的测距精度要求,具有一定工程应用价值。