Anti‐inflammatory bioactive equivalence of combinatorial components β‐carboline alkaloids identified in Arenaria kansuensis by two‐dimensional chromatography and solid‐phase extraction coupled with liquid–liquid extraction enrichment technology

Bioactive equivalent combinatorial components play a critical role in herbal medicines. However, how to discover and enrich them efficiently is a question for herbal pharmaceuticals researchers. In our work, a novel two‐dimensional reversed‐phase/hydrophilic interaction high‐performance liquid chromatography method was established to perform real‐time components trapping and combining for preparation and isolation of coeluting components. Arenaria kansuensis was taken as an example, and solid‐phase extraction coupled with liquid–liquid extraction as a simple and efficient method for enriching trace components, reversed phase column coupled with hydrophilic interaction liquid chromatography XAmide column as two‐dimensional chromatography technology for isolation and preparation of coeluting constituents, enzyme‐linked immune‐sorbent assay as bio‐guided assay, and anti‐inflammatory bioactivity evaluation for bioactive constituents. A combination of 12 β‐carboline alkaloids was identified as anti‐inflammatory bioactive equivalent combinatorial components from A. kansuensis , which accounts for 1.9% w/w of original A. kansuensis . This work answers the key question of which are real anti‐inflammatory components from A. kansuensis and provides a fast and efficient approach for discovering and enriching trace β‐carboline alkaloids from herbal medicines for the first time. More importantly, the discovery of bioactive equivalent combinatorial components could improve the quality control of herbal products and inspire a herbal medicine based on combinatorial therapeutics.     

光学玻璃应力双折射叠加

为解决在光学玻璃应力双折射测量中遇到的双折射叠加问题,利用光学等效原理,使用一个线性双折射模型和一个旋转器来代替叠加模型。对叠加的情况做了分析和计算,得到了叠加后的特征延迟、主应力方向和旋转角随两个应力模型主应力方向夹角变化的曲线。理论分析表明,应力双折射叠加不是应力双折射的简单相加,而是与叠加模型各自的应力双折射值和主应力方向的夹角有关。实验结果与理论计算相吻合。应力双折射叠加对实际光学玻璃测试造成不良影响,使测量精度降低,特别是有透光支撑机构或折射液容器的情况下,应力双折射叠加的影响不可忽略。     

Relative difference sets,graphs and inequivalence of functions between groups

For cryptographic purposes, we want to find functions with both low differential uniformity and dissimilarity to all linear functions and to know when such functions are essentially different. For vectorial Boolean functions, extended affine equivalence and the coarser Carlet–Charpin–Zinoviev (CCZ) equivalence are both used to distinguish between nonlinear functions. It remains hard to tell when CCZ equivalent functions are EA‐inequivalent. This paper presents a framework for solving this problem in full generality, for functions between arbitrary finite groups. This common framework is based on relative difference sets (RDSs). The CCZ and EA equivalence classes of perfect nonlinear (PN) functions are each derived, by quite different processes, from equivalence classes of splitting semiregular RDSs. By generalizing these processes, we obtain a much strengthened formula for all the graph equivalences which define the EA equivalence class of a given function, amongst those which define its CCZ equivalence class. © 2010 Wiley Periodicals, Inc. J Combin Designs 18: 260–273, 2010     

Schur Q-polynomials, multiple hypergeometric series and enumeration of marked shifted tableaux

We study Schur Q-polynomials evaluated on a geometric progression, or equivalently q-enumeration of marked shifted tableaux, seeking explicit formulas that remain regular at q=1. We obtain several such expressions as multiple basic hypergeometric series, and as determinants and pfaffians of continuous q-ultraspherical or continuous q-Jacobi polynomials. As special cases, we obtain simple closed formulas for staircase-type partitions.     

Solving clusterization problems using groups of algorithms

Clusterization is one of the most widespread problems in data analysis. There are many approaches and methods for its solution. However, the result of clusterization strongly depends on the choice of the feature space, on the object proximity measures, and on the method used to formalize the concepts of the object and cluster equivalence. As a result, different solutions can be far apart from each other; they can be degenerate or be quite different from the actually existing groupings. In this paper, clusterization obtained by groups of algorithms is considered; these methods make it possible to construct consistent solutions that best match the actually existing groupings.     

Nondurable K-Theory Equivalence and Bousfield Localization*

In this paper we consider what happens when Adams self maps are modified by adding certain unstable maps. The unstable maps which are added are trivial after a single suspension. We can choose the modification so that the maps are still K-theory equivalences but the loops on the map are no longer K-theory equivalences. As a corollary we note that the maps are K-theory equivalences but not v ₁-periodic equivalences. Another consequence is the behavior of the cobar spectral sequences for generalized homology theories. Tamaki shows that in certain cases a cobar-type spectral sequence for generalized homology theories is well behaved. The maps we construct give an example where despite the connectivity of the spaces the cobar spectral sequence is still poorly behaved. Finally we use our maps to construct spaces whose Bousfield class is distinct from the cofiber of the Adams map but which becomes the same after one suspension.     

Creep life evaluation of aluminum conductor composite core utilized in high voltage electric transmission

The creep life of aluminum conductor composite core (ACCC) utilized in high voltage electric transmission was investigated using an experimental method based on the equivalence relationship. First, the time-temperature-stress equivalence relationship was developed using the time-temperature and the time-stress equivalence relationships. Then, tensile creep experiments were conducted under different temperatures and different stress levels to obtain the strain-time curves of the ACCC. Finally, the creep strain master curve was obtained using the experimental data based on the time-temperature-stress equivalence relationship, allowing prediction of ACCC creep life. The results will play an important role in evaluation of the long-term characteristics of the ACCC for engineering applications.     

冷原子介质中基于相干诱导高反射带和高透射带的全光路由控制

以相干诱导光子带隙结构为工作基础,提出了一种可对两个弱光信号的传播路径同时进行动态调控的新型全光路由控制方案。利用描述光波在空间周期介质中相干散射的传输矩阵理论,结合描述单频激光与多能级原子共振相互作用的密度矩阵方程,计算了作为控制媒介的相干驱动超冷原子系综的稳态反射光谱和稳态透射光谱。结果表明,通过改变两个较强相干激光的空间模式、强度和频率等参数,可在探测跃迁共振频率附近建立反射率约为95%或者透射率约为95%的两个特殊频带。对这样的相干诱导高反射带和高透射带进行了实时动态调控,可根据需要引导两个不同频率的弱光信号进入指定的网络通道。该方案很好地满足了在量子信息处理领域对弱光信号进行全光路由控制时的低损耗和低形变要求。     

有限重数的Dirichlet移位

In this paper, we show that a multiplication operator on the Dirichlet space D is unitarily equivalent to Dirichlet shift of multiplicity n ＋ 1 （n ≥ 0） if and only if its symbol is c zn＋1 for some constant c. The result is very different from the cases of both the Bergman space and the Hardy space.