通过不对称氢转移/动态动力学拆分合成碳环N^3-嘌呤核苷

N^3-嘌呤核苷由于可能同时被嘌呤和嘧啶代谢酶识别,因而有望作为双靶点药物应用于抗病毒治疗.报道了一种以α-(N^3-嘌呤)取代的环烷酮为原料,通过不对称氢转移反应实现动态动力学拆分,高收率高立体选择性地合成系列碳环N^3-嘌呤核苷化合物.该催化体系也适用于α-嘧啶取代的环烷酮底物,且产物通过进一步衍生,合成了2’-F-,Ac S-,N^3-修饰的碳环嘧啶核苷.     

基于实物期权的双源供应链柔性采购协调策略

在需求不确定下,由风险规避的供应商和占主导地位的零售商组成的二级供应链中,构建了在现货市场影响下基于实物期权的双源柔性采购协调模型,给出了实现供应链协调的最优期权参数的求解算法,探讨了现货市场价格不确定性和供应商风险规避特性对零售商采购策略和双方利润的影响。研究结果表明,在考虑现货市场影响和供应商风险规避的条件下,实物期权契约可以实现供应链协调。     

关于L_p球的几个新不等式和性质(英文)

本文研究了L_p球的相关问题.利用对偶混合体积、球面Radon变换和Fourier变换的方法,获得了关于L_p球的几个新不等式和性质,其中一个不等式与著名的最大切片猜想有关.     

多层前馈模糊神经网络在儿童综合素质测评中的应用

运用对偶标度统计方法计算儿童发展调查问题中原始数据的变量权和样本得分,从而确定评价因素集.采用多层前馈模糊神经网络——FM LP实现对儿童个体综合素质的定量评价.     

气体和气溶胶在多孔介质中迁移的数值模拟

为了研究多孔介质对气体和气溶胶的封闭能力,用数值方法模拟了气体和气溶胶在多孔介质中的迁移.考虑了渗透、吸附过滤、扩散、热传导等因素,在柱对称坐标下用双孔双渗模型进行了数值模拟,并与实验结果进行了比较.计算结果显示,多孔介质对气溶胶有较强的阻挡作用,模拟实验结果也证明了这一点.     

电磁波导的奇异元与对偶有限元分析

基于电磁波导的对偶变量变分原理以及Hamilton正则方程,将含有奇异性的电磁场问题导入Hamilton体系下进行分析,通过分离变量及共轭辛本征函数向量展开法,构造出可以表征电磁场奇异性的奇异解析元。奇异元的采用克服了普通单元处理含有导电劈和介质楔的波导问题的困难,同时能够方便地与电磁对偶元相结合,保持了有限元方法的灵活性,具有较高的精度。     

A study of gridless method with dynamic clouds of points for solving unsteady CFD problems in aerodynamics

When solving unsteady computational fluid dynamics problems in aerodynamics with a gridless method, a cloud of points is usually required to be regenerated due to its accommodation to moving boundaries. In order to handle this problem conveniently, a fast dynamic cloud method based on Delaunay graph mapping strategy is proposed in this paper. A dynamic cloud method makes use of algebraic mapping principles and therefore points can be accurately redistributed in the flow field without any iteration. In this way, the structure of the gridless clouds is not necessarily changed so that the clouds regeneration can be avoided successfully. The spatial derivatives of the mathematical modeling of the flow are directly determined by using weighted least‐squares method in each cloud of points, and then numerical fluxes can be obtained. A dual time‐stepping method is further implemented to advance the two‐dimensional Euler equations in arbitrary Lagarangian–Eulerian formulation in time. Finally, unsteady transonic flows over two different oscillating airfoils are simulated with the above method and results obtained are in good agreement with the experimental data. Copyright © 2009 John Wiley & Sons, Ltd.     

Operators on the orthogonal complement of the Dirichlet space(Ⅱ)

In this paper we first prove that a dual Hankel operator R φ on the orthogonal complement of the Dirichlet space is compact for φ∈ W 1,∞(D),and then that a semicommutator of two Toeplitz operators on the Dirichlet space or two dual Toeplitz operators on the orthogonal complement of the Dirichlet space in Sobolev space is compact.We also prove that a dual Hankel operator R φ with φ∈ W 1,∞(D) is of finite rank if and only if B φ is orthogonal to the Dirichlet space for some finite Blaschke product B,and give ...