Optimal allocation of reliability tasks to mitigate faults during system development

^** Email: walter.johnston{at}baesystems.com^*** Email: j.quigley{at}strath.ac.uk^**** Email: lesley.walls{at}strath.ac.uk This paper considers reliability planning for a concept designfor a new system where a portfolio of possible reliability developmenttasks exists; the goal is to find a selection and sequence oftasks to achieve reliability targets subject to time constraintsat minimal cost. This is non-trivial given that each task potentiallycan expose several different weaknesses and each weakness potentiallycan be exposed by several different tasks. We use a Bayesianpoint process model to estimate the system reliability. Theprior distribution maps to a fault register and relates directlyto a set of potential engineering modifications.The likely impactof each task can be assessed using the point process model.An integer programming approach is used to sequence and scheduletasks under the constraint that contractual reliability requirementsmust be met. An illustrative example is provided and an extensionto system availability is proposed.     

At-column heating and a resistively heated, liquid-cooled thermal modulator for a low-resource bench-top GC x GC

A transportable GC x GC instrument is under development for on-site applications that would benefit from the enhanced resolution and powers of detection, which can be achieved by this method. In the present study, a low-resource GC x GC instrument using an electrically heated and liquid-cooled single-stage thermal modulator that requires no cryogenic materials is evaluated. The instrument also uses at-column heating, thus eliminating the need for a convection oven to house the two columns. The stainless-steel modulator tube is coated with PDMS, which can be heated to 350 degrees C for sample injection into the second-dimension column. The modulator is cooled to -30 degrees C by a 100 mL/min flow of PEG by means of a commercial liquid chiller and a small recirculating pump. Resistive heating of the modulator tube is provided by a programmable power supply, which uses a voltage program that results in increasing modulator temperature during an analysis. This, together with more rapid cooling by the use of a liquid cooling medium, results in reduced solute breakthrough following each heating cycle as the modulator cools to a temperature where quantitative trapping resumes. As a result, modulated peak widths at half-height of less than 40 ms are observed. Design and performance details are presented along with chromatograms of gasoline and an essential oil sample.     

Label-free characterization of cell adhesion using reflectometric interference spectroscopy (RIfS)

Reflectometric interference spectroscopy (RIfS) is a label-free, time-resolved technique for detecting interactions of molecules immobilized on a surface with ligands in solution. Here we show that RIfS also permits the detection of the adhesion of tissue culture cells to a functionalized surface in a flow system. Interactions of T cells with other leukocytes or epithelial cells of blood vessels are crucial steps in the regulating immune response and inflammatory reactions. Jurkat T cell leukemia cells rapidly attached to a transducer functionalized with a monoclonal antibody directed against the T cell receptor (TCR)/CD3 complex, followed by activation-dependent cell spreading. RIfS curves were obtained for the Jurkat derivative JCaM 1.6 (which lacks the key signaling protein Lck), cells preincubated with cytochalasin D (an inhibitor of actin polymerization), and for surfaces functionalized with an antibody directed against the coreceptor CD28. These curves differed with respect to the maximum signal and the initial slope of the increase in optical thickness. The testing of chemical inhibitors, cell surface molecules and gene products relevant to a key event in T cell immunity illustrates the potential of label-free techniques for the analysis of activation-dependent cell-surface contacts. The first two authors contributed equally to this paper     

Examining the design features of a communication-rich,problem-centred mathematics professional development

While there is considerable scholarship describing principles for effective professional development, there have been few attempts to examine these principles in practice. In this paper, we identify and examine the particular design features of a mathematics professional development experience provided for middle grades teachers over 14 weeks. The professional development was grounded in a set of mathematical tasks that each had one right answer, but multiple solution paths. The facilitator engaged participants in problem solving and encouraged participants to work collaboratively to explore different solution paths. Through analysis of this collaborative learning environment, we identified five design features for supporting teacher learning of important mathematics and pedagogy in a problem-solving setting. We discuss these design features in depth and illustrate them by presenting an elaborated example from the professional development. This study extends the existing guidance for the design of professional development by examining and operationalizing the relationships among research-based features of effective professional development and the enacted features of a particular design.     

Enhancing Formative Assessment Practice and Encouraging Middle School Mathematics Engagement and Persistence

In the transition to middle school, and during the middle school years, students' motivation for mathematics tends to decline from what it was during elementary school. Formative assessment strategies in mathematics can help support motivation by building confidence for challenging tasks. In this study, the authors developed and piloted a professional development program, Learning to Use Formative Assessment in Mathematics with the Assessment Work Sample Method (AWSM) to build middle school math teachers' understanding of the characteristics of high‐quality formative assessment processes and increases their ability to use them in their classrooms. AWSM proved to be feasible to implement in the middle school setting. It improved teachers' practice of formative assessment, especially in their feedback practices, regardless of their pedagogical content knowledge at entry. Results from focus groups suggested that teachers were better able to implement ungraded practice and student self‐ and peer‐assessment after AWSM, and that students were more willing to engage in complex problem solving.     

Facilitating an Elementary Engineering Design Process Module

STEM education in elementary school is guided by the understanding that engineering represents the application of science and math concepts to make life better for people. The Engineering Design Process (EDP) guides the application of creative solutions to problems. Helping teachers understand how to apply the EDP to create lessons develops a classroom where students are engaged in solving real world problems by applying the concepts they learn about science and mathematics. This article outlines a framework for developing such lessons and units, and discusses the underlying theory of systems thinking. A model lesson that uses this framework is discussed. Misconceptions regarding the EDP that children have displayed through this lesson and other design challenge lessons are highlighted. Through understanding these misconceptions, teachers can do a better job of helping students understand the system of ideas that helps engineers attack problems in the real world. Getting children ready for the 21st century requires a different outlook. Children need to tackle problems with a plan and not shrivel when at first, they fail. Seeing themselves as engineers will help more underrepresented students see engineering and other STEM fields as viable career options, which is our ultimate goal.     

Conditions and decisions of urban elementary teachers regarding instruction of STEM curriculum

The study was situated in a National Science Foundation supported Math Science Partnership between a private university and an urban school district. This study sought to understand the decision‐making process of elementary teachers as they implement an integrated science, technology, engineering, and mathematics (STEM) curriculum in their classrooms and the interactions that occur between the teachers and curriculum during that process. This qualitative study utilized a comparative case study approach to understanding the decision‐making process of three elementary teachers enacting the same lesson. Analysis of the interactions revealed that the teachers' perceptions of student ability, their pedagogical design capacity, and time were influences that impacted implementation. These findings have implications for STEM‐focused professional development of elementary teachers.     

基于高校发展战略、教师合理绩效激励与高校发展成果的薪酬激励研究

以东部高校教师绩效收入为样本,基于高校发展战略分别从教师绩效收入三个方面分析发展战略的差异是否导致薪酬激励的差异;各种发展战略分别与何种薪酬激励方式相匹配。分析结果表明高校在选择教师绩效激励模式时应考虑自身发展战略,同时尽量做到绩效激励的合理化。对于高校教师薪酬激励体系设计具有一定的现实意义。     

油砂开发经济性评价方法研究及应用

随着我国油企进入加拿大油砂行业,如何降低油砂开发项目的风险并提高决策的科学性变得愈发重要。油砂开采的经济性作为投资决策的重要着力点,研究相应的经济评价方法也就有了十分重要的意义。本文较为全面的分析了露天开发油砂及蒸汽辅助重力卸油技术(SAGD)开发油砂的技术特点;选择折现现金流理论作为理论基础分别构建了露天开发与SAGD开发油砂项目经济评价模型,并对模型中涉及的收入、投资、成本等参数的估算方法进行了系统的研究;通过对新疆某油砂试采区的实际评价,验证了方法的可行性。该方法作为油砂开发项目经济评价的初步探索,将为加拿大和我国油砂开发项目的经济评价工作提供一定的参考依据。     

Manufacturer cooperation in supplier development under risk

Supplier development involves efforts undertaken by manufacturing firms to improve their suppliers’ capabilities and performance. These improvement efforts can be targeted at a variety of areas such as quality management, product development, and cost reduction. Since supplier development requires investments on the part of the manufacturer, it is important to optimally allocate investment dollars among multiple suppliers to minimize risk while maintaining an acceptable level of return. This paper presents a set of optimization models that address this issue. We consider two scenarios: single-manufacturer and multiple suppliers (SMMS) and two-manufacturer and multiple suppliers (TMMS). In the SMMS case, we suggest optimal investments in various suppliers by effectively considering risk and return. The TMMS case investigates whether manufacturers with differing capabilities could gain risk reduction benefits from cooperating with each other in supplier development. Through illustrative applications, we identify conditions in which both cooperation and non-cooperation are beneficial for manufacturers. Under conditions of cooperation, we propose optimal investments for manufacturers to achieve high levels of risk reduction benefits.