非线性光环路镜去复用理论研究

本文从非线性光环路镜(NOLM)的一般原理出发,研究了NOLM的一般特性,发现利用光纤的双折射李效应并通过合理地选择波长能减小群色散的影响,降低开关光功率.在忽略群色散条件下,研究了光开关功率、消光比与控制脉冲抖动大小和文中定义的参数d的变化关系.     

Conformational energy downward driver (CEDD): Characterization and calibration of the method

Summary A method has been developed that allows one to drive a molecule to conformations of lowest energy given the starting conformation, the identity of the rotatable bonds and the step size. This method has proved useful in our hands in the drug design arena where it is frequently more important to get low-energy conformers of a molecule that match some other (e.g. pharmacophoric or enzyme pocket) requirements than to exhaustively enumerate all possible low-energy conformations for each of the molecules to be studied. The method has been shown to work in the test cases studied to date. Furthermore, so far it has been shown to be sufficiently fast to be used for molecules containing up to 70 rotatable bonds.     

相位调制边带失衡问题研究

 高功率激光系统中一般利用相位调制器对单纵模激光进行频谱展宽以避免受激布里渊散射，当后继系统中的滤波器存在中心波长偏差时，则会导致相位调制产生的边带失衡，使光信号出现较为严重的高频起伏。基于前端系统模拟平台对此问题进行了数值模拟研究，结果表明滤波后的高频起伏随滤波器带宽变窄和中心波长偏差增大而加剧。分析表明0.2 nm带宽的滤波器出现0.05 nm左右的波长偏差时，将引起24.3%左右的顶部起伏。实验中根据分析将滤波器带宽从0.2 nm加大到0.4 nm，成功将脉冲顶部起伏从25.2%减小到了4.4%，对前端系统的研制起到了很好的指导作用。     

An analytical approach for on-site analysis of breath samples for Δ9-tetrahydrocannabinol (THC)

Increased acceptance of cannabis containing the psychoactive component, Δ9-tetrahydrocannabinol (THC), raises concerns about the potential for impaired drivers and increased highway accidents. In contrast to the “breathalyzer” test, which is generally accepted for determining the alcohol level in a driver, there is no currently accepted roadside test for THC in a motorist. There is a need for an easily collectible biological sample from a potentially impaired driver coupled with an accurate on-site test to measure the presence and quantity of THC in a driver. A novel breath collection device is described, which includes three separate sample collectors for collecting identical A, B, and C breath samples from a subject. A simple one-step ethanol extraction of the “A” breath collector sample can be analyzed by UHPLC/selected ion monitoring (SIM) liquid chromatography/mass spectrometry (LC/MS) to provide qualitative and quantitative determination of THC in breath sample in less than 4 min for samples collected up to 6 h after smoking a cannabis cigarette. SIM LC/MS bioanalyses employed d3-THC as the stable isotope internal standard fortified in negative control breath samples for quantitation including replicates of six calibrator standards and three quality control (QC) samples. Subsequent confirmation of the same breath sample in the B collectors was then confirmed by a reference lab by LC/MS/MS analysis. Fit-for-purpose bioanalytical validation consistent with pharmaceutical regulated bioanalyses produced pharmacokinetic (PK) curves for the two volunteer cannabis smokers. These results produced PK curves, which showed a rapid increase of THC in the breath of the subjects in the first hour followed by reduced THC levels in the later time points. A simpler single-point calibration curve procedure with calibrators and QC prepared in ethanol provided similar results. Limitations to this approach include the higher cost and operator skill sets for the instrumentation employed and the inability to actually determine driver impairment.     

用于爆轰驱动的射流起爆实验研究

爆轰驱动激波风洞的自由来流模拟范围与驱动气体的爆轰极限密切相关,爆轰极限越宽则模拟范围越大。驱动气体一般是通过点火管进行起爆的,提高点火管的起爆能力可以拓宽爆轰极限。为了提高点火管起爆能力,就点火管口径、点火气体爆轰敏感性和单/双点火管3种因素的影响进行了实验研究。在不同的点火管初始条件下,对驱动段波速进行了测量。结论如下:(1)提高点火管口径可以显著提升起爆能力;(2)点火气体爆轰敏感性对起爆能力有影响,点火管为缩径内型面时,低敏感性气体起爆能力更强,点火管为等径内型面时则低敏感性气体和高敏感性气体的起爆能力大体持平;(3)在保证射流同步的前提下,双点火管能够提高起爆能力,为保证射流同步性需使用化学恰当比的氢氧混气等爆轰敏感性强的点火气体。     

自由活塞激波风洞

自由活塞激波风洞是一种使用自由活塞压缩器驱动的高焓脉冲型激波风洞。这种风洞是由R J Stalker提出并在澳大利亚国立大学首先建成和逐渐发展起来的高焓实验设备。经过30多年的改进与发展,日趋完善,现已成为研究高超声速气动加热、计及真实气体效应的气体动力学现象、特别是超声速或高超声速燃氢冲压发动机(scamjet)的重要设备之一,受到国际上航空航天界的重视。本文概述了自由活塞激波风洞的发展过程,系统地阐述了这种设备的结构特点和运行原理,给出了性能参数的计算方法和算例,及其性能指标,并讨论了这类风洞的优缺点。      

高功率固体激光驱动器的优化设计

扼要介绍了高功率固体激光系统物理设计中的一些基本概念 ,并阐述了系统优化设计的主要方法。针对神光 原型装置的物理设计 ,提出了其能流分布设计优化的判据和设计的限制条件 ,给出了原型装置主放大级的初步优化设计结果。     

Effects of shear thinning on migration of neutrally buoyant particles in pressure driven flow of Newtonian and viscoelastic fluids

The pattern of cross stream migration of neutrally buoyant particles in a pressure driven flow depends strongly on the properties of the suspending fluid. These migration effects have been studied by direct numerical simulation in planar flow. Shear thinning has a large effect when the inertia or elasticity is large, but only a small effect when they are small. At moderate Reynolds numbers, shear thinning causes particles to migrate away from the centerline, creating a particle-free zone in the core of the channel, which increases with the amount of shear thinning. In a viscoelastic fluid with shear thinning, particles migrate either toward the centerline or toward the walls, creating an annular particle-free zone at intermediate radii. The simulations also give rise to precise determination of slip velocity distributions in the various cases studied.     

高功率激光放大器脉冲的整形设计

 针对惯性约束聚变实验对激光驱动器脉冲波形的要求,将优化控制模型理论运用于计算激光放大器输入脉冲的预补偿波形,得到了与实验基本一致的结果。同时给出了我国新一代高功率激光器“神光 Ⅲ”装置主放大器级输入脉冲波形的设计要求。     

Driver Countries in Global Banking Network

We analyze the network of cross-border bank lending connections among countries from 1977 to 2018. The network includes core countries that lend money and peripheral countries that borrow money from core countries. In nowadays highly connected banking network, financial crisis that start from a country can spread to other countries very fast and cause global affects. We use principal component analysis (PCA) to find the influential lending (core) countries in this network over the years and clusters of borrowing (peripheral) countries related to these impactful core countries. We find three clusters of peripheral countries, with some constant and some changing members over time. This can be a sign of changes in the financial or political interactions among countries. The changes in the role of core countries and how these roles get affected by the important financial crisis in the past decades is investigated. Among 31 of core countries, 7 countries have a partially or constantly important role in the network including France, United Kingdom, United States, Japan, Germany, Chinese Taipei and Switzerland.