Nmr and Mass Spectroscopic Studies of the Competitive-Angiotensin II Antagonist “Sarmesin”

Fast atom bombardment mass spectrometry (FAB-MS) and high resolution (400 Mz) proton nuclear magnetic resonance (NMR spectroscopy) on the competitive angiotensin II antagonist, |Sar¹, Tyr(Me)⁴ (ANGII (Sarmesin) and its he-ptapeptide homolog, [Tyr(Me)³ |ANGIII, yield spectra which provide confirmation of structure and molecular weight. The characteristics of the spectra are discussed and compared with the spectra of natural ANG II, ANG III and |Sar¹|ANG II. The NMR data are suggestive of interactions in angiotensin between: 1) the phenolic hydroxyl group and the imidazole ring, and 2) the N-terminal amino group and the Tyrring. These interactions may be important for the formation of the proposed charge transfer system in angiotensin II involving the phenoxyl and α-carboxylate groups.     

Laser drilling of stainless steel with nanosecond double-pulse

Nanosecond double-pulse laser drilling is reported in this paper. The double-pulse herein represents two closely conjoint pulses with 21 ns pulse duration and about 52 ns interpulse separation, which are acquired by temporal pulse shaping. Percussion drilling with such double-pulse is performed in stainless steel samples with different laser fluences, sample's thickness, repetition rates and ambient pressures. The experimental results show that the drilling rates of double-pulse drilling are more than one order of magnitude higher than that of conventional single-pulse drilling in air. Differences in the processing results between single-pulse and double-pulse with various processing parameters are investigated. In addition the ablation mechanisms of the double-pulse drilling are discussed.     

Nonlinear optical properties of stimulated Brillouin scattering process in submerged object detection

Nonlinear optical properties of stimulated Brillouin scattering(SBS)to signal detection in water are analyzed.With the threshold characteristics,SBS only occnrs when the high power laser is focused in the SBS cell.When there is an object present in front of the focus,it leads to lower incident intensity and then SBS does not occur.The backward SBS signal depends on the focusing location.The nonlinear optical properties of SBS process in the focusing regime axe analyzed theoretically.With the object coming near to the focusing center,the backward Stokes signal rises up from zero to a maximum,and then grows to saturation.The delay time of the echo signal to pump signal can give the object location.In experiment,the peak position of varying rate of energy can give object location.     

Laser frequency stabilization based on Sagnac interferometric spectroscopy

A simple method based on Sagnac interferometric spectroscopy (SIS) is applied for frequency stabilization of diode lasers. Sagnac interferometric spectra of rubidium vapor are investigated both theoretically and experimentally. The interference signal at the output of the Sagnac interferometer displays a sharp dispersion feature near the atomic resonance. This dispersion curve is used as the feedback error signal to stabilize the laser frequency. Linewidth of a diode laser is stabilized down to 1 MHz by this modulation-free method.     

Testifying experiment of the multi-pulse phenomena of capillary discharge soft-X-ray laser

In a capillary discharge experiment for the neon-like argon lasing, we have proposed an experimental scheme to verify that the multi-spike of X-ray diode (XRD) signal is a multi-pulse laser or is a reflection of the laser pulse in the XRD.The ceramic capillary has an inner diameter of 3mm and a length of 200mm.At the gas pressure of 28Pa and discharge current of 27kA, stable lasing has been realized.The experimental results prove that the multi-spike of XRD signal is a reflection of the electromagnetic signal produced by the laser pulse in the XRD.The improved electrocircuit scheme of the XRD to minimize the reflection phenomena is also found.     

Optical system and lens design for Blu-ray disc optical pick-up

During the design process of Blu-ray disc optical pick-up (BD OPU), the optical system and the collimator lens design is especially important. This paper designs an optical system and some lenses for the BD OPU, including collimator lens, beam shaping lens for laser beam shaping, and cylinder lens for signal detecting. In this OPU, we use a triplet lens to collimate the laser beam. At the same time, we build a series of assembly jigs to make sure that each lens can be put into the OPU basement properly. At last, we get the reading spot image and S-curve photo of OPU, which can be used to read Blu-ray disc (BD).     

A study of time over threshold (TOT) technique for plastic scintillator counter

A new charge measurement method, time over threshold (TOT), has been used in some gas detectors lately. Here TOT is studied for TOF system, made of plastic scintillator counter, which can simplify the electronics of the system. The signal characteristics are measured and analyzed with a high quality oscilloscope, including noise, pedestal, signal amplitude, total charge, rise time and the correlation between them. The TOT and charge are related and can be fitted by some empirical formula. The charge measurement resolution by TOT is given and this will help the design of TOF electronics.     

基于SOS的脉冲功率源技术新进展

 研制了基于SOS的胡杨200和胡杨700脉冲功率源。给出了胡杨200和胡杨700的电路原理、组成结构和实验波形。介绍了在SOS脉冲功率源上开展的高重复频率强流电子束产生、长寿命阴极实验、绝缘介质的高重复频率击穿实验和低引导磁场无箔二极管等实验研究进展。经测试，胡杨200在2 kHz重复频率、负载阻抗200 Ω下，输出电压200 kV，脉冲宽度约35 ns，平均输出功率大于10 kW；在300 Hz条件下可连续运行。胡杨700同样为全固态脉冲功率源，其设计指标:输出电压700 kV，电流5 kA，脉冲宽度约40 ns；经初步调试在150 Ω电阻负载上单脉冲输出指标达到660 kV，4.4 kA，脉宽约70 ns。     

测量脉冲大电流的四光路光学电流传感器技术

 在传统光学电流传感器技术的基础上，提出了一种四光路光学电流传感器，其通过四路输出信号可准确确定偏转角，使电流的测量范围不受正弦函数的单调性的限制，从而提高了电流的测量范围。配合四光路结构，提出了新的反正切函数数据处理方法，其不存在角度不灵敏区、可纠正原始数据的缺陷，从而提高了测量精度。实测了充电电压为4.5 kV、电容为50 μF和导线有效穿过磁光探头14次的快开快门的总短路电流，其峰值达85 kA，与理论值87 kA能较好地吻合，从而证明了四光路光学电流传感器可有效地测量脉冲大电流。     

同轴快沿脉冲源研制与测试

 利用脉冲高压陶瓷电容器和高气压小间隙开关，研制了60 kV同轴式高压快沿脉冲源。利用自行研制的薄膜式电容分压器和同轴式电阻分压器对快沿脉冲源的输出参数进行测量，分析了薄膜式电容分压器的测试原理，对电容分压中二级电阻分压器元件的参数进行了优化。当脉冲源负载为50 W时，测得脉冲源输出电压的前沿小于2.3 ns，半高宽约28 ns，符合IEC电磁脉冲的最新标准。