Sensitive pseudobienzyme electrocatalytic DNA biosensor for mercury(II) ion by using the autonomously assembled hemin/G-quadruplex DNAzyme nanowires for signal amplification

Herein, a novel sensitive pseudobienzyme electrocatalytic DNA biosensor was proposed for mercury ion (Hg²⁺) detection by using autonomously assembled hemin/G-quadruplex DNAzyme nanowires for signal amplification. Thiol functionalized capture DNA was firstly immobilized on a nano-Au modified glass carbon electrode (GCE). In presence of Hg²⁺, the specific coordination between Hg²⁺ and T could result in the assembly of primer DNA on the electrode, which successfully triggered the HCR to form the hemin/G-quadruplex DNAzyme nanowires with substantial redox probe thionine (Thi). In the electrolyte of PBS containing NADH, the hemin/G-quadruplex nanowires firstly acted as an NADH oxidase to assist the concomitant formation of H₂O₂ in the presence of dissolved O₂. Then, with the redox probe Thi as electron mediator, the hemin/G-quadruplex nanowires acted as an HRP-mimicking DNAzyme that quickly bioelectrocatalyzed the reduction of produced H₂O₂, which finally led to a dramatically amplified electrochemical signal. This method has demonstrated a high sensitivity of Hg²⁺ detection with the dynamic concentration range spanning from 1.0 ng L⁻¹ to 10 mg L⁻¹ Hg²⁺ and a detection limit of 0.5 ng L⁻¹ (2.5 pM) at the 3S_blank level, and it also demonstrated excellent selectivity against other interferential metal ions.     

Drag amplification of long flexible riser models undergoing multi-mode VIV in uniform currents

Measurement data of long flexible riser models are used to study the drag amplification due to multi-mode vortex induced vibration (VIV). The riser model was towed in a towing tank, and vibration along its length was measured indirectly at a set of discrete points using accelerometers, along with the total drag and lift forces on the model. These data were used to fit expressions for the drag amplification taking into account the spatial variation of the vibration amplitude along the riser length. The results were compared with the existing empirical expression used in the VIV analysis tool SHEAR7 as well as other test data. It was found that the expression in SHEAR7 agrees well with the test data. However, for larger vibration amplitudes, it appears to under-predict the drag amplification.     

增益饱和在啁啾脉冲放大中的影响

研究了增益饱和在啁啾脉冲放大中的影响，发现由于增益饱和在存在，压缩后脉冲的信噪比会下降，而且展宽器附加的色散也会降低输出的信噪比，这种降低对应着一定的光谱畸变。通过对展宽／压缩器作用的分析，提示了啁啾脉冲放大中光谱与光强的内在联系，提出利用非共振放大来修正光谱畸变提高放大压缩后的信噪比。     

Amplification of spontaneous emission in Nd~(3 )-doped fiber pumped by Ti: Al_2O_3 tunable laser

Amplification of spontaneous emission(ASE) in 4m Nd~(3 )-doped fiber pumped by Ti : Al~2O_3 tunable laser is studied theoretically and experimentally. The output of 2.64mW from ASE source pumped at 833 nm is obtained and the experimental results of ASE source are compared with that of Nd~(3 )-doped fiber ring laser.     

BBO，LBO，KDP晶体光参量啁啾脉冲放大特性的比较研究

 对BBO，LBO，KDP晶体I类非共线匹配下的光参量啁啾脉冲放大的相位匹配、参量范围、增益特性等进行了理论分析，重点对BBO和LBO的光参量啁啾脉冲放大特性进行了比较。结果表明对于以光参量啁啾脉冲放大系统代替800nm中心波长的Ti:sappire再生放大系统，用BBO晶体可获得更宽的增益带宽，而对1 053nm中心波长的种子光用LBO晶体更好。     

Small-signal amplification of period-doubling bifurcations in smooth iterated maps

Various authors have shown that, near the onset of a period-doubling bifurcation, small perturbations in the control parameter may result in much larger disturbances in the response of the dynamical system. Such amplification of small signals can be measured by a gain defined as the magnitude of the disturbance in the response divided by the perturbation amplitude. In this paper, the perturbed response is studied using normal forms based on the most general assumptions of iterated maps. Such an analysis provides a theoretical footing for previous experimental and numerical observations, such as the failure of linear analysis and the saturation of the gain. Qualitative as well as quantitative features of the gain are exhibited using selected models of cardiac dynamics.     

Beam Recombination Characteristics in Array Laser Amplification Using Stimulated Brillouin Scattering Phase Conjugation

Beam recombination characteristics were numerically investigated in array laser amplification using stimulated Brillouin scattering phase conjugation. To clarify the effect of piston errors due to imperfect phase locking, spatial intensity profiles of the beam recombination output were calculated in both the near and the far field on the basis of Rayleigh-Sommerfeld diffraction theory. The analyses indicate that piston errors are seriously detrimental to the quality of a beam recombination output and should be eliminated by a proper phase locking. It is also found that the gap between the beam splitting-combining wedges has a negligible effect.Presented at 1996 International Workshop on Interferometry (IWI ‘96), August 27-29, Saitama, Japan.     

Studies of the chemically amplified development-free vapor photolithography

Development-free vapor photolithography (DFVP) is a unique all-dry pattern transfer technique, which is based on the reaction of SiO₂ with HF vapor under a polymer film in the presence of accelerators at a temperature of above 100°C. In this paper, we found that the etching reaction could be catalyzed by superacids. Based on this discovery, a novel, chemically amplified, development-free vapor photolithography technique was developed, and has benn successfully applied to power electronic device manufacture.