Detecting pipe changes via acoustic matched field processing

Detecting pipe irregularities such as intrusions can be challenging. However, subtle changes can be identified in the complex acoustic fields measured over a range of frequencies and over a time interval given an “array” of receivers. In particular, for two receivers one can coherently process the signals via matched field processing (MFP) to infer whether or not there have been changes such as new intrusions relative to undisturbed fields measured earlier. There is no acoustic modelling of the fields required, only the simple linear processor is applied, and only test data (five scenarios) are used in this demonstration. A key advantage to using MFP plus two (or more) microphones is that absolute sound levels need not be carefully measured.     

Permeability of R6G across Cx43 hemichannels through a novel combination of patch clamp and surface enhanced Raman spectroscopy

We have measured the permeability of rhodamine-6G across Cx43 hemichannels reconstituted on a pipette tip. Cx43 hemichannels were overexpressed in Sf9 cells, and affinity-purified. The hemichannels were reconstituted in a lipid bilayer on a pipette tip by the tip-dip method. R6G in the pipette permeated across the channels into the bath. The permeability of R6G was quantified by measuring R6G concentration in the bath after several hours by surface enhanced Raman spectroscopy (SERS) with 100 nm silver colloid particles. The ratio of the permeability of dye to salt, as extracted by this combined electrical-SERS technique, is compatible with similar ratios for other dyes across whole gap junction channels. The results for the permeability ratio were further compared to fluorescence measurements. The novel combination of patch and SERS techniques can be extended to quantifying the transport of biologically significant non-fluorescent molecules, such as cAMP and IP3, across 1 nm sized pores, such as the gap junction channel.     

Slow and fast light: basic concepts and recent advancements based on nonlinear wave‐mixing processes

After a review of the basic concepts of slow and fast light, recent advancements based on nonlinear wave‐mixing processes are described. As a nonlinear medium, the authors focus on a liquid crystal light valve showing that it allows obtaining a large control of the group delay, with a maximum fractional delay of 1, and a deceleration of light pulses down to group velocities as small as 0.2 mm/s. A theoretical model accompanies the observations and accounts for them in the general framework of two‐wave mixing in the light valve. At the end, a high‐sensitivity interferometer is presented as an example of slow light applications.     

Low-pass filters and representations of the Baumslag Solitar group

We analyze representations of the Baumslag Solitar group

that admit wavelets and show how such representations can be constructed from a given low-pass filter. We describe the direct integral decomposition for some examples and derive from it a general criterion for the existence of solutions for scaling equations. As another application, we construct a Fourier transform for some Hausdorff measures.

     

Theory of Systems of Rodlike Particles: I. Athermal systems

An improved treatment of the lattice model proposed in 1956 is presented for a system of hard rods, with axial ratio x, dispersed in a diluent. Interparticle forces, apart from repulsions on contact, are deliberately ignored within the scope of the present paper. The equilibrium distribution of orientations of the rodlike particles in a phase with nematic order is derived and explicitly taken into account. Thermodynamic properties in the asymptotic limit of high degree of order reduce approximately. to those obtained previously. Calculations carried out for equilibrium between anistropic (nematic) and isotropic phases yield ν′_x/ν_x = 1.4653 for the ratio of volume fractions in the respective phases in the limit x → ∞. The product xν_x, expressing the combined covolume of solute species in the isotropic phase at coexistence is 7.89 in the same limit. The calculated critical value of the axial ratio for coexistence of the two phases in the neat liquid is x_crit, = 6.417. Results are compared with those of other theories. Those that rely on the virial expansion are subject to errors implicit in treating the solvent as a continuum.     

Wave propagation analysis in buried pipe conveying fluid

A study of wave propagation in buried pipe conveying fluid is presented in the paper. The Flüggle shell model is adopted for pipe and surrounding solid is modeled as elastic matrix by using Winkle model. Wave dispersion curves of a buried vacant pipe and a pipe conveying fluid are obtained numerically by considering coupling conditions. Results show that wave velocity exhibits sharp drop points in dispersion curves, and remains to an identical values before and after the points for both of vacant pipe and pipe conveying fluid. Effects of wall thickness, elastic matrix properties and fluid velocity are also discussed.     

弱激光诱导神经元兴奋性改变的实验研究

利用全细胞膜片钳技术研究弱激光诱导下大鼠海马CA3区锥体神经元兴奋性.实验结果显示：弱激光作用使神经元钠通道激活电位向超极化方向移动,钠电流幅度增大,且这种增大作用具有电压依赖性和可逆性.激光作用显著影响钠电流稳态激活与失活特性,对照组和照射组通道半数激活电压分别为(-4414±528)mV和(-5655±614)mV(n=8,P<001),半数失活电压分别为(-6902±1031)mV和(-5660±897)mV(n=8, P<0 关键词： 钠离子通道 膜片钳技术 弱激光 动作电位 神经元     

Global dynamics of a pipe conveying pulsating fluid in primary parametrical resonance: Analytical and numerical results from the nonlinear wave equation

The chaotic dynamics of nonlinear waves in the harmonic-forced fluid-conveying pipe in primary parametrical resonance, is explored analytically and numerically. The multiple scale method is applied to obtain an equivalent nonlinear wave equation from the complicated nonlinear governing equation describing the fluid conveyed in a pipe. With the Melnikov method, the persistence of a heteroclinic structure is shown to be satisfied and its condition is given in functional form. Similarly, for the heteroclinic orbit, using geometric analysis, a condition function of the stable manifold is derived for the orbit to return to the stable manifold from the saddle point. The persistent homoclinic structures and threshold of chaos in the Smale-horseshoe sense are obtained for the fluid-conveying pipe under both conditions, indicating how the external excitation amplitude can change substantially the global dynamics of the fluid conveyed in the pipe. A numerical approach was used to test the prediction from theory. The impact of the external excitation amplitude on the nonlinear wave in the fluid-conveying pipe was also studied from numerical simulations. Both theoretical predications and numerical simulations attest to the complex chaotic motion of fluid-conveying pipes.     

低温液体管路输送中几个问题的分析

对低温液体传输过程中气体置换、预冷过程、竖直管道中间歇泉现象、盲支管填充时和阀门开启时的不稳定现象作了较详细分析,指出了其可能造成的危害,并提出了相应的解决方法。