Thermal decomposition of a generation 4.5 PAMAM dendrimer platinum drug conjugate

A nanoscale multivalent platinum drug based on a poly(amidoamine) [PAMAM] dendrimer (generation 4.5, carboxylate surface) has been synthesized and fully characterized using a variety of spectroscopic, chromatographic and thermal methods. Treatment of the dendrimer with an aqueous solution containing an excess diaquo(cis-1,2-diaminocyclohexane)platinum(II) produces a conjugate containing approximately forty (diaminocyclohexane)platinum(II) moieties at the surface of the dendrimer. This material undergoes smooth two-stage thermal decomposition to provide residual platinum oxide reflecting the platinum loading in the drug.     

Analysis of Decomposition Algorithms with Benders Cuts for p-Median Problem

In this paper the algorithms for solving the p-median problem based on the Benders decomposition are investigated. A family of problems hard for solving with such algorithms is constructed and then generalized to a special NP-hard case of the p-median problem. It is shown that the effectiveness of the considered algorithms depends on the choice of the optimal values of the dual variables used in Benders cuts. In particular, the depth of the cuts can be equal to one.     

一致Lipschitz映射的遍历定理及其遍历分解

设(X,d)是一个可分的度量空间,Cu(X,d)是由全体一致连续函数所组成的C(X,d)的子空间,T是定义在X上的一致Lipschitz映射,那么对f∈Cu(X),1/n n∑k=1 Uk If在Cu(X)上收敛.从这个基本结果出发,利用Cu(X,d)的共扼空间的表示定理,得到了相空间的Yosida型遍历分解;利用空间的嵌入技术证明了非一致Lipschitz映射的大数法则.     

Stratifiable Families of Extremals and Sufficient Conditions for Optimality in Optimal Control Problems

It is shown that, if a parametrized fämily of extremals F can be stratified in a way compatible with the flow map generated by F, then those trajectories of the family which realize the minimal values of the cost in F are indeed optimal in comparison with all trajectories which lie in the region R covered by the trajectories of F. It is not assumed that F is a field covering the state space injectively. As illustration, an optimal synthesis is constructed for a system where the flow of extremals exhibits a simple cusp singularity.     

Maximin share and minimax envy in fair-division problems

For fair-division or cake-cutting problems with value functions which are normalized positive measures (i.e., the values are probability measures) maximin-share and minimax-envy inequalities are derived for both continuous and discrete measures. The tools used include classical and recent basic convexity results, as well as ad hoc constructions. Examples are given to show that the envy-minimizing criterion is not Pareto optimal, even if the values are mutually absolutely continuous. In the discrete measure case, sufficient conditions are obtained to guarantee the existence of envy-free partitions.     

D-N交替法与Schwartz交替法的收敛关系分析

This paper has demonstrated that the Schwartz alternating process must converge if D-N alternating process has converged. Its technique is that the overlapping regions in Schwartz alternating process are considered as independent domains, then Schwartz alternating process could be transformed into D-N alter-nating process. Finally the convergence estimation of Schwartz alternating process could be obtained. The results show that its convergence rate is same as that of D-N alternating process.     

Group classification of unsteady boundary layer equations of a class of non-Newtonian fluids

Two dimensional unsteady boundary layer equations of a general model of non-Newtonian fluids were investigated in this study. In this model, the shear stress is taken as an arbitrary function of the velocity gradient. Group classification of the equations with respect to shear stress is done using two different approaches: (1) classical theory (2) equivalence transformations. Both approaches yield identical results. It is found that the principle Lie Algebra extends only for cases of Newtonian and Power-Law flows.     

Optimal Control of Magnetohydrodynamic Equations with State Constraint

This work is concerned with the maximum principle for optimal control problem governed by magnetohydrodynamic equations, which describe the motion of a viscous incompressible conducting fluid in a magnetic field and consist of a subtle coupling of the Navier-Stokes equation of viscous incompressible fluid flow and the Maxwell equation of electromagnetic field. An integral type state constraint is considered.     

Cube factorizations of complete graphs

A cube factorization of the complete graph on n vertices, K_n, is a 3‐factorization of K_n in which the components of each factor are cubes. We show that there exists a cube factorization of K_n if and only if n ≡ 16 (mod 24), thus providing a new family of uniform 3‐factorizations as well as a partial solution to an open problem posed by Kotzig in 1979. © 2004 Wiley Periodicals, Inc.     

The Computational Complexity of the Chow Form

We present a bounded probability algorithm for the computation of the Chowforms of the equidimensional components of an algebraic variety. In particular, this gives an alternative procedure for the effective equidimensional decomposition of the variety, since each equidimensional component is characterized by its Chow form. The expected complexity of the algorithm is polynomial in the size and the geometric degree of the input equation system defining the variety. Hence it improves (or meets in some special cases) the complexity of all previous algorithms for computing Chow forms. In addition to this, we clarify the probability and uniformity aspects, which constitutes a further contribution of the paper. The algorithm is based on elimination theory techniques, in line with the geometric resolution algorithm due to M. Giusti, J. Heintz, L. M. Pardo, and their collaborators. In fact, ours can be considered as an extension of their algorithm for zero-dimensional systems to the case of positive-dimensional varieties. The key element for dealing with positive-dimensional varieties is a new Poisson-type product formula. This formula allows us to compute the Chow form of an equidimensional variety from a suitable zero-dimensional fiber. As an application, we obtain an algorithm to compute a subclass of sparse resultants, whose complexity is polynomial in the dimension and the volume of the input set of exponents. As another application, we derive an algorithm for the computation of the (unique) solution of a generic overdetermined polynomial equation system.