导数分光光度—阻尼因子矩阵法同时测定三元混合组分

本文提出导数分光光度阻尼因子矩阵法同时测定带有辅料或其它呈一次或二次曲线干扰吸收的多元混合组分的基本原理和实验方法。以同时测定止喘咳糖浆中盐酸苯海拉明,盐酸麻黄碱,咳必清为例,研究了方法的可靠性和测量的适宜条件。结果满意。     

Synthesis of New Types of N‐Arylpiperazine Phosphoramide Analogues of Chrysin

Several N‐arylpiperazine phosphoramide analogues of chrysin are synthesized through a facile phosphorylated reaction for the first time. Their structures are elucidated by NMR, ESI MS, IR and Element analysis. The results showed that the phosphorylation action occurred regioselectively only at the hydroxyl group of 7 position of chrysin.     

Derivative reproducing properties for kernel methods in learning theory

The regularity of functions from reproducing kernel Hilbert spaces (RKHSs) is studied in the setting of learning theory. We provide a reproducing property for partial derivatives up to order s when the Mercer kernel is C^2s. For such a kernel on a general domain we show that the RKHS can be embedded into the function space C^s. These observations yield a representer theorem for regularized learning algorithms involving data for function values and gradients. Examples of Hermite learning and semi-supervised learning penalized by gradients on data are considered.     

Steffensen type methods for solving nonlinear equations

In the present paper, by approximating the derivatives in the well known fourth-order Ostrowski’s method and in a sixth-order improved Ostrowski’s method by central-difference quotients, we obtain new modifications of these methods free from derivatives. We prove the important fact that the methods obtained preserve their convergence orders 4 and 6, respectively, without calculating any derivatives. Finally, numerical tests confirm the theoretical results and allow us to compare these variants with the corresponding methods that make use of derivatives and with the classical Newton’s method.     

Synthesis and physicochemical properties of the Al(III), Ga(III) and In(III) complexes with chrysin

New solid compounds of Al(III), Ga(III) and In(III) with chrysin were obtained. Their composition and some physicochemical properties were studied by thermogravimetric analysis, UV-vis, infrared and solid state ¹³C NMR spectroscopies. Upon heating the hydrated compounds M(C₁₅H₉O₄)₃·nH₂O decomposed to the oxides. The structure of the compounds was elucidated on the basis of obtained results.     

Simultaneous analysis of ellagic acid and coenzyme Q(10) by derivative spectroscopy and HPLC

Antioxidants are gaining tremendous interest as chemopreventive as well as chemotherapeutic agents. Ellagic acid (EA) is a plant derived compound with very poor solubility in water and very low octanol/water partition coefficient and coenzyme Q₁₀ (CoQ₁₀) is a highly lipophilic compound, which is synthesized in the body and can be derived from food supplements as well. The new insights in the combination therapy are promising a better future in many challenging diseases. Synergism is among the key advantages of combination therapy apart from decreased intensity of unwanted effects of a compound, increased patient compliance and reduction in cost of therapy. EA and CoQ₁₀ supplementation in combination will be beneficial in strengthening the weakened antioxidant defense system in many diseases related to oxidative stress. Here we report first derivative UV spectroscopic and HPLC methods for the simultaneous analysis of these two agents in pharmaceutical preparations. Results obtained indicate that the derivative spectroscopy is as efficient as HPLC method in quantitative analysis. Retention of ellagic acid can be increased using PEG bonded column which is poorly retained on C₁₈ column. PEG column can be used for rapid simultaneous analysis of EA and CoQ₁₀, which are having diverse physicochemical properties.     

荧光光谱法研究共存物对白杨素与BSA相互作用的影响

运用荧光光谱法研究了共存物亚硝酸钠、葡萄糖或维生素C对白杨素(CHR)与牛血清白蛋白(BSA)相互作用的影响.结果表明:无共存物时,白杨素对BSA的荧光猝灭过程为静态猝灭,结合常数K值为10~3～10~4数量级,结合位点数n近似等于1,分子间相互作用力以疏水作用力为主;亚硝酸钠、葡萄糖、维生素C分别参与下,白杨素对BSA的荧光猝灭类型由静态猝灭转变为动态猝灭,葡萄糖的参与使白杨素与BSA之间作用力类型由疏水作用力转为氢键与范德华力,亚硝酸钠或维生素C的分别存在不影响白杨素与BSA的作用力类型;三种外加试剂的单独参与均使得白杨素与BSA的结合常数明显增大,结合位点数略有增加,但仍维持在1左右.初步探讨了共存物影响白杨素与BSA结合的可能方式.     

Derivative polynomials and closed-form higher derivative formulae

In a recent paper, Adamchik [1] expressed in a closed-form symbolic derivatives of four functions belonging to the class of functions whose derivatives are polynomials in terms of the same functions. In this sequel, simple closed-form higher derivative formulae which involve the Carlitz-Scoville higher order tangent and secant numbers are derived for eight trigonometric and hyperbolic functions.