Novel low‐loss waveguide delay lines using Vernier ring resonators for on‐chip multi‐λ microwave photonic signal processors

In this paper, novel photonic delay lines (DLs) using Vernier/non‐identical ring resonators (VRRs) are proposed and demonstrated, which are capable of simultaneous generation of multiple different delays at different wavelengths (frequencies). The simple device architectures and full reconfigurability allow the DLs to be integrated with other functional building blocks in photonic integrated circuits to realize on‐chip, complex multi‐λ microwave photonic signal processors with reduced system complexity. To prove the concept, DLs using VRRs in cascaded and coupled configurations have been fabricated in TriPleX^TM waveguide technology, which enables a very low delay‐induced loss of approximately 0.18 dB/100 ps. The fabricated DLs demonstrated simultaneous generation of four incremental delays, where a maximum incremental step of 550 ps and a corresponding top delay of 1650 ps were measured for a bandwidth up to 1 GHz. To our knowledge, this is the first report on VRRs for delay generation functionalities.     

III‐V/silicon photonics for on‐chip and intra‐chip optical interconnects

In this paper III‐V on silicon‐on‐insulator (SOI) heterogeneous integration is reviewed for the realization of near infrared light sources on a silicon waveguide platform, suitable for inter‐chip and intra‐chip optical interconnects. Two bonding technologies are used to realize the III‐V/SOI integration: one based on molecular wafer bonding and the other based on DVS‐BCB adhesive wafer bonding. The realization of micro‐disk lasers, Fabry‐Perot lasers, DFB lasers, DBR lasers and mode‐locked lasers on the III‐V/SOI material platform is discussed.     

Vesicles displaying aggregation-induced emission: Fabrication and applications

Vesicles displaying aggregation induced emission are very promising in fields related to biology. In this review, we summarized recent progresses in the creation of such vesicles and their applications. The following contents are included: 1) the general background of AIE vesicles; 2) creation of AIE vesicles with synthetic covalent compounds; 3) creation of AIE vesicles with supramolecular chemistry; 4) the application of AIE vesicles in real-time imaging, visualized drug delivery, cell communication and fission-fusion process, and light-harvesting. Finally, we envision AIE vesicles may have profound impact on medical science, biological science and material science.     

Advances in nitric oxide-releasing hydrogels for biomedical applications

Hydrogels provide a plethora of advantages to biomedical treatments due to their highly hydrophilic nature and tissue-like mechanical properties. Additionally, the numerous and widespread endogenous roles of nitric oxide have led to an eruption in research developing biomimetic solutions to the many challenges the biomedical world faces. Though many design factors and fabrication details must be considered, utilizing hydrogels as nitric oxide delivery vehicles provides promising materials in several applications. Such applications include cardiovascular therapy, vasodilation and angiogenesis, antimicrobial treatments, wound dressings, and stem cell research. Herein, a recent update on the progress of NO-releasing hydrogels is presented in depth. In addition, considerations for the design and fabrication of hydrogels and specific biomedical applications of nitric oxide-releasing hydrogels are discussed.     

Exploring the Research Progress about the Applications of Cyclodextrins and Nanomaterials in Electroanalysis

Cyclodextrins and nanomaterials are widely used in the achievement of powerful platforms in supramolecular chemistry and nanotechnology. The relatively hydrophobic internal cavity of the CDs selectively retains molecules having the proper geometry, while the hydrophilic exterior allows CDs to improve the dispersibility and molecular recognition. The nanomaterials provide higher surface area, good conductivity, and electrocatalytic effect. The use of nanomaterials and CDs in electrochemical sensors’ design allows the development of a large variety of devices, explaining the increasing number of papers in the last years that are discussed in this review.     

Target-Specific Bioorthogonal Reactions for Precise Biomedical Applications

Bioorthogonal chemistry is a promising toolbox for dissecting biological processes in the native environment. Recently, bioorthogonal reactions have attracted considerable attention in the medical field for treating diseases, since this approach may lead to improved drug efficacy and reduced side effects via in situ drug synthesis. For precise biomedical applications, it is a prerequisite that the reactions should occur in the right locations and on the appropriate therapeutic targets. In this minireview, we highlight the design and development of targeted bioorthogonal reactions for precise medical treatment. First, we compile recent strategies for achieving target-specific bioorthogonal reactions. Further, we emphasize their application for the precise treatment of different therapeutic targets. Finally, a perspective is provided on the challenges and future directions of this emerging field for safe, efficient, and translatable disease treatment.     

Biological activities from andiroba (Carapa guianensis Aublet.) and its biotechnological applications: A systematic review

Carapa guianensis is a tree from Meliaceae family traditionally known as andiroba that has a wide range of biological properties, including therapeutic effects, antioxidant activities, insecticidal and repellent effects that can be used in biotechnological approaches to medicine, agriculture, and cosmetic products. Therefore, we aim to explore the biological activities exhibited by this species and their respective biotechnological applications of interest. For this, a systematic review was carried out following the PRISMA guidelines dated from 1993 to 2022 through the Scopus, Web of Science and Agricultural Research Database (Base de Dados da Pesquisa Agropecuária - BDPA), screened for biological activity/bioactive compounds. A total of 129 studies were included in the PRISMA flow analysis. Biological properties and major bioactive compounds, as well as biotechnological approaches could be identified. The biological activity from C. guianensis could be observed in different vegetative parts through diverse methods of extractions. These activities are mainly due to the unsaturated fatty acids and bioactive compounds, such as the limonoids and a small fraction of phenolic compounds. Gedunin-type limonoids, like gedunin and its derivatives, represent the class of compounds that show the highest bioactivities in different applications.