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21.
A particle method is applied to the investigation of impact biomechanics in the case of penetrating ballistic. A three dimensional model is proposed using the Smoothed Particle Hydrodynamics (SPH) method combined with Finite Elements (FE) method. The problem consists in the violent impact of a steel sphere on soft tissues, simulated by 20% ballistic gelatine (BG) material which is considered as a very interesting human tissue surrogate. Comparisons with experimental data are established to validate the proposed model. The results, in terms of penetrating curves, show very promising results. The use of particle methods appears to be an interesting way to model high speed loading, especially penetrating ballistic impact whose classical FE modelling can bring some important limitations in terms of mesh and element distortions. 相似文献
22.
The poroelastic problem associated with a hollow cylinder under cyclic loading is solved. Both fluid and solid phases are supposed compressible. Solid matrix is modeled as an elastic transverse isotropic material. An explicit close-form solution for the steady state is obtained. This cylinder is considered as a model for an osteon, the basic unit of cortical bone. The fluid flow distribution as a function of poroelastic properties and cyclic loading is discussed, as this could influence bone remodeling. To cite this article: A. Rémond, S. Naili, C. R. Mecanique 332 (2004). 相似文献
23.
General mechanical considerations provide an upper bound for the take-off velocity of any jumper, animate or inanimate, rigid or soft body, animal or vegetal. The take-off velocity is driven by the ratio of released energy to body mass. Further, the mean reaction force on a rigid platform during push-off is inversely proportional to the characteristic size of the jumper. These general considerations are illustrated in the context of Alexander's jumper model, which can be solved exactly and which shows an excellent agreement with the mechanical results. 相似文献
24.
25.
The term ‘synergy’ – from the Greek synergia – means ‘working together’. The concept of multiple elements working together towards a common goal has been extensively used in neuroscience to develop theoretical frameworks, experimental approaches, and analytical techniques to understand neural control of movement, and for applications for neuro-rehabilitation. In the past decade, roboticists have successfully applied the framework of synergies to create novel design and control concepts for artificial hands, i.e., robotic hands and prostheses. At the same time, robotic research on the sensorimotor integration underlying the control and sensing of artificial hands has inspired new research approaches in neuroscience, and has provided useful instruments for novel experiments.The ambitious goal of integrating expertise and research approaches in robotics and neuroscience to study the properties and applications of the concept of synergies is generating a number of multidisciplinary cooperative projects, among which the recently finished 4-year European project “The Hand Embodied” (THE). This paper reviews the main insights provided by this framework. Specifically, we provide an overview of neuroscientific bases of hand synergies and introduce how robotics has leveraged the insights from neuroscience for innovative design in hardware and controllers for biomedical engineering applications, including myoelectric hand prostheses, devices for haptics research, and wearable sensing of human hand kinematics. The review also emphasizes how this multidisciplinary collaboration has generated new ways to conceptualize a synergy-based approach for robotics, and provides guidelines and principles for analyzing human behavior and synthesizing artificial robotic systems based on a theory of synergies. 相似文献
26.
Electrospun nanofibers are of the same length scale as the native extracellular matrix and have been extensively reported to facilitate adhesion and proliferation of cells and to promote tissue repair and regeneration. With a primary focus on tissue repair and regeneration using electrospun scaffolds, only a few studies involved electrospun nanofiber scaffolds directing cell behaviors have been reported. In this study, we prepared electrospun nanofiber scaffolds with distinct fiber configurations, namely, random and aligned orientations of nanofibers, as well as oriented yarns, and investigated their effects on cell behaviors. Our results showed that these scaffolds supported good proliferation and viability of murine fibroblasts. Fiber configuration profoundly influenced cell morpho-logy and orientation but showed no effects on cell proliferation rate. The yarn scaffold had comparable total protein accumulation with the random and aligned scaffolds, but it supported a greater pro-liferation rate of fibroblasts with significantly elevated collagen de-position due to its porous fibrous configuration. Cell-seeded yarn scaffolds showed a greater Young's modulus compared with cell-free controls as early as 1 week. Together with its unique fiber configuration similar to the native extracellular matrix of the myocardium, the yarn scaffold might be a suitable matrix material for modeling cardiac fibrotic disorders. 相似文献
27.
Claudio Storck Raphael Gehrer Claude Fischer Markus Wolfensberger Flurin Honegger Gerhard Friedrich Markus Gugatschka 《Journal of voice》2011,25(5):632-637
Objectives/Hypothesis
Cricothyroid approximation (CTA) surgery aims at raising the voice pitch in male-to-female transsexuals. However, 30% of the patients are not satisfied with the result. The purpose of our study was to examine the cricothyroid joint (CTJ) biomechanics and to analyze if (and how) the CTJ anatomy influences the movement of the cricoid and, consequently, the elongation of the vocal fold and the voice pitch after CTA.Methods
Twenty-four cadaver larynges were examined with high-resolution computerized tomography and MIMICS three-dimensional imaging software (Materialise Interactive Medical Image Control System, Leuven, Belgium). After superimposing the two scans taken in “neutral” and in “CTA” positions, vector geometrical analysis was used to determine the effective rotation axis of the CTJ and to calculate the elongation of the vocal folds after CTA.Results
Our results showed that the cricoid rotates around an axis, the position of which depends on the anatomical structure of the CTJ. Based on the location of this effective rotation axis, we could distinguish three groups. In group I (N = 13), the rotation axis was located in the lower third; in group II (N = 5), it was located in the middle third; and in group III (N = 6), it was located in the upper third of the cricoid. The elongations of the vocal fold were 12%, 8%, and 3%, in groups I, II, and III, respectively.Conclusions
The anatomical structure of the CTJ influences directly (1) the position of the effective rotation axis and (2) the elongation of the vocal folds. 相似文献28.
《International Journal of Solids and Structures》2014,51(21-22):3579-3588
In this paper, six new invariants associated with an anisotropic material made of one fiber family are calculated by presenting a systematic constructive and original approach. This approach is based on the development of mathematical techniques from the theory of invariants:
- •Definition of the material symmetry group.
- •Definition of the generalized Reynolds Operator.
- •Calculation of an integrity basis for invariant polynomials.
- •Comparison between the new (constructed) invariants and the classical ones.
29.
B. R. Wienke 《Il Nuovo Cimento D》1986,8(4):417-435
Summary Transfer mechanisms and critical pressures are essential elements in decompression calculations and staged procedures. By
coupling a multitissue transfer model to fitted critical pressures, decompression data can be synthesized for rapid numerical
implementation in applications. Parametric fits to the critical nitrogen pressures are generated for the six tissue compartments
(5, 10, 20, 40, 80, 120 min) at seal-evel with both linear and constant-pressure ratio extrapolations to altitude conveniently
effected with the barometer equation. The macroscopic model used to transfer nitrogen in tissues is described and functional
forms of the fit equations are motivated. Accurate exponential representations for mantle pressures and the well-known Cross
altitude factors are also generated. Fitted critical tensions vary inversely as the approximate fourth root of the tissue
half-life and increase linearly with depth. Air mantle pressures decrease exponentially with altitude and inverse temperature.
Using bounce dive constraints, a set of single-tissue decay coefficients, which increase logarithmically with depth, are extracted
from depth-dependent decompression criteria and contrasted with corresponding multitissue decay parameters. Bend statistics
and a decompression titration experiment, which predicts decreasing critical ratios at depth, are discussed. Overlapping predictions
of the models and correlations with experiment are identified.
Riassunto I meccanismi di trasferimento e le pressioni critiche sono elementi essenziali nei calcoli della decompressione e nelle procedure a stadi. Accoppiando un modello di trasferimento a molti tessuti e pressioni critiche adattate, i dati di decompressione possono essere sintetizzati per un rapido incremento numerico nelle applicazioni. Approssimazioni parametriche alle pressioni critiche dell'azoto sono generate per sei componenti del tessuto (5, 10, 20, 40, 80, 120 min) a livello del mare con estrapolazioni sia lineari che a pressione costante del rapporto ad un'altitudine convenientemente ottenuta con l'equazione barometro. Si descrive il modello macroscopico per trasferire azoto nei tessuti e si forniscono le motivazioni delle forme funzionali delle equazioni di approssimazione. Sono anche prodotte accurate rappresentazioni esponenziali per pressioni mantello ed i ben noti fattori di altitudine di Cross. Le tensioni critiche approssimate variano inversamente come la radice quarta approssimata della vita media del tessuto ed aumentano in maniera lineare con la profondità. Le pressioni del mantello d'aria diminuiscono esponenzialmente con l'altitudine e la temperatura inverse. Usando costanti di immersione di rimbalzo, un gruppo di coefficienti di decadimento di singoli tessuti, che aumentano logaritmicamente con la profondità, è estratto dai criteri di decompressione dipendenti dalla profondità ed è in contrasto con il parametro di decadimento a molti tessuti. La statistica dei piegamenti ed un esperimento di titolazione della decompressione, che prevede rapporti critici decrescenti in profondità, sono discussi. Si identificano le previsioni sovrapposte dei modelli e correlazioni con l'esperimento.相似文献
30.
G. Bao 《Experimental Mechanics》2009,49(1):153-164
Proteins play essential roles in all aspects of cellular processes, such as biosynthesis, division, growth, motility, metabolism, signaling, and transmission of genetic information. Proteins, however, could deform under mechanical forces, thus altering their biological functions. Here we present protein deformation as a possible molecular basis for mechanosensing and mechanotransduction, elucidate the important features of protein mechanics including protein deformation mode and dynamics, illustrate how protein deformation could alter biological function, and describe the important roles of protein deformation in force-sensing, force transducing and mechanochemical coupling in cells. The experimental and modeling challenges in protein mechanics are discussed. 相似文献