Pattern recognition system for the discrimination of multiple sclerosis from cerebral microangiopathy lesions based on texture analysis of magnetic resonance images

In this study, a pattern recognition system has been developed for the discrimination of multiple sclerosis (MS) from cerebral microangiopathy (CM) lesions based on computer-assisted texture analysis of magnetic resonance images. Twenty-three textural features were calculated from MS and CM regions of interest, delineated by experienced radiologists on fluid attenuated inversion recovery images and obtained from 11 patients diagnosed with clinically definite MS and from 18 patients diagnosed with clinically definite CM. The probabilistic neural network classifier was used to construct the proposed pattern recognition system and the generalization of the system to unseen data was evaluated using an external cross validation process. According to the findings of the present study, statistically significant differences exist in the values of the textural features between CM and MS: MS regions were darker, of higher contrast, less homogeneous and rougher as compared to CM.     

深水环境下隔水管的横向自由振动分析

隔水管是海洋钻井工程中的必要设备。在深水环境下,隔水管的疲劳失效问题普遍存在,隔水管的强烈振动是导致其失效的主要原因之一。本文采用微元法,得到了隔水管在各种载荷作用下的横向振动规律及其横向振动的固有频率的分布规律,进一步分析了各种因素对隔水管横向振动固有频率的影响。结果表明:隔水管的长度增加时,固有频率减小;随着顶部张力比的增加,隔水管的横向振动的固有频率也增加;随着壁厚的增加,隔水管横向振动的固有频率逐渐降低;而随着钻井液密度的增加,隔水管横向振动的固有频率增加;海水的存在使隔水管的横向振动固有频率降低。该研究有利于避免隔水管在使用过程中出现强烈的共振现象,为减小隔水管的失效提供了理论依据。     

Synthesis and mesomorphic properties of 2,4-bis(4′-n-pentyloxybenzoyloxy)- benzylidine-4″- n-alkoxyaniline

The synthesis and mesomorphic properties of a new series of 2,4-bis(4′-npentyloxybenzoyloxy)- benzylidine-4″ -n-alkoxyaniline (DC5An) are reported. The molecular structure of compounds was confirmed by FTIR, ¹H-NMR, ¹³C-NMR, mass spectroscopy and elemental analysis. The mesomorphic properties were studied by differential scanning calorimetry (DSC) and polarizing optical microscopy (POM) measurements. All compounds of the series exhibit nematic (N) and smectic C (SmC) phases. The first four homologues (DC5A1-DC5A4) display a N mesophase, whereas the highest homologues (DC5A5-DC5A10) exhibit an enantiotropic dimorphism N and SmC phases. The mesomorphic properties of the present series are compared and discussed with other structurally related series.     

具有纵向辅助耗尽衬底层的新型横向双扩散金属氧化物半导体场效应晶体管

为了优化横向双扩散金属氧化物半导体场效应晶体管(lateral double-diffused MOSFET,LDMOS)的击穿特性及器件性能,在传统LDMOS结构的基础上,提出了一种具有纵向辅助耗尽衬底层(assisted depletesubstrate layer,ADSL)的新型LDMOS.新加入的ADSL层使得漏端下方的纵向耗尽区大幅向衬底扩展,从而利用电场调制效应在ADSL层底部引入新的电场峰,使纵向电场得到优化,同时横向表面电场也因为电场调制效应而得到了优化.通过ISE仿真表明,当传统LDMOS与ADSL LDMOS的漂移区长度都是70μm时,击穿电压由462 V增大到897 V,提高了94%左右,并且优值也从0.55 MW/cm~2提升到1.24 MW/cm~2,提升了125%.因此,新结构ADSL LDMOS的器件性能较传统LDMOS有了极大的提升.进一步对ADSL层进行分区掺杂优化,在新结构的基础上,击穿电压在双分区时上升到938 V,三分区时为947 V.     

低阈值单横模852nm半导体激光器

基于波导理论、等效折射率方法,设计并制备了非对称波导隔离双沟结构脊型边发射激光器,最终获得了低闽值单基侧模852 nm激光器.详细研究了不同脊型台深宽比参数设计对激光器侧向模式特性的影响规律,实现了腔面未镀膜情况下脊型波导边发射激光器的单基侧模稳定输出,同时激射波长可以精确调谐到852 nm;工作电流达到150 mA,工作温度30℃;斜率效率最高可达0.89 nW/mA,光谱半宽小于1 nm.研究结果为进一步实现超窄线宽激光器提供了参考和借鉴,并且为实现激光器稳定输出提供了实验基础.     

前方小切口入路治疗股骨颈骨折的围术期指标观察

目的研究前方小切口入路治疗股骨颈骨折的围术期指标观察。方法选取湖北省孝感市中心医院2011年2月—2013年7月收治的98例股骨颈骨折患者,抽签随机分为对照组和观察组各49例。对照组患者采用传统后外侧入路切开复位术,观察组采用前外侧小切口入路复位术,观察两组围术期相关指标。结果观察组手术切口(7.8±1.1)cm较对照组(15.3±1.7)cm明显较小,术中出血量(107.2±21.4)m L较对照组(187.4±32.1)m L明显较低,具有统计学意义(P0.05);观察组骨折愈合率100%较对照组89.80%明显较高,观察组并发症率4.08%较对照组16.33%显著较低,具有统计学意义(P0.05)。结论前方小切口入路术切口小,术中出血量低且术后并发症较少,有利于股骨颈骨折患者病情恢复。     

Angular reconstruction of a lead scintillating-fiber sandwiched electromagnetic calorimeter

The Neighbor Cell Deposited Energy Ratio （NCDER） is a new method that is proposed to reconstruct incidence position in a single layer for a 3-dimensional imaging electromagnetic calorimeter （ECAL）. This method was applied to reconstruct the ECAL test beam data for the Alpha Magnetic Spectrometer-02 （AMS-02）. The results show that this method can achieve an angular resolution of 7.36±0.08°/√E＋0.28±0.02° in the determination of the photon＇s direction, which is much more precise than that obtained with the commonly-adopted Center of Gravity （COG） method （8.4±0.1°/E＋0.8±0.3°）. Furthermore, since it uses only the properties of electromagnetic showers, this new method could also be used for other type of fine grain sampling calorimeters.     

荧光显微镜研究极端pH值诱导磷脂支撑膜的侧向再组织

利用荧光显微镜研究了极端pH值诱导支撑磷脂双层膜的侧向再组织.结果表明,在强酸/强碱性溶液中,流动性较好的二油酰磷脂酰胆碱支撑膜出现破裂、分离、出芽或生出微管等与细胞内吞和外排相似的现象.基于极性分子与H+/H3O+或OH-的相互作用,以电中性的磷脂首基为核吸附溶液中的H+/H3O+或OH-.当磷脂膜上下叶吸附的电荷量不同时,引起两叶有效面积差,即磷脂膜曲率不对称,从而诱发磷脂膜出现各种结构和动力学的响应.本研究有助于理解极端环境对生物膜的影响,为研究生物膜的形变过程提供了参考.     

Fast-switching SOI-LIGBT with compound dielectric buried layer and assistant-depletion trench

A lateral insulated gate bipolar transistor (LIGBT) based on silicon-on-insulator (SOI) structure is proposed and investigated. This device features a compound dielectric buried layer (CDBL) and an assistant-depletion trench (ADT). The CDBL is employed to introduce two high electric field peaks that optimize the electric field distributions and that, under the same breakdown voltage (BV) condition, allow the CDBL to acquire a drift region of shorter length and a smaller number of stored carriers. Reducing their numbers helps in fast-switching. Furthermore, the ADT contributes to the rapid extraction of the stored carriers from the drift region as well as the formation of an additional heat-flow channel. The simulation results show that the BV of the proposed LIGBT is increased by 113% compared with the conventional SOI LIGBT of the same length L_D. Contrastingly, the length of the drift region of the proposed device (11.2 μ) is about one third that of a traditional device (33 μ) with the same BV of 141 V. Therefore, the turn-off loss (E_OFF) of the CDBL SOI LIGBT is decreased by 88.7% compared with a conventional SOI LIGBT when the forward voltage drop (V_F) is 1.64 V. Moreover, the short-circuit failure time of the proposed device is 45% longer than that of the conventional SOI LIGBT. Therefor, the proposed CDBL SOI LIGBT exhibits a better V_F-E_OFF tradeoff and an improved short-circuit robustness.     

欠采样包裹相位图的展开算法

利用四种常见算法对由球面参考光像面数字全息显微术得到的中药饮片海金沙细胞的包裹相位图进行了相位解包裹。结果表明:基于离散余弦的最小二乘算法和预条件共轭梯度算法会使欠采样区域的误差进行传递,使得解包裹相位产生较大误差;质量图导向路径跟踪算法由于未识别残差点,导致出现拉线或者孤岛区域,而且处理速度很慢;基于横向剪切干涉的最小二乘算法处理欠采样包裹相位图的效果最好,而且处理速度较快。