Novel trichothecanes, paecilomycine A, B, and C, isolated from entomopathogenic fungus, Paecilomyces tenuipes

Paecilomycine A (1), B (2), and C (3) were isolated from cultivated fruiting bodies of Paecilomyces tenuipes (Isaria japonica), which is a popular entomopathogenic fungus used in folk medicine and health foods in China, Korea, and Japan. The structures of 1-3 were deduced from their spectroscopic data and their absolute configurations were elucidated by preparing their MPA esters. Compound 1 showed activity in the neurotrophic factor biosynthesis in glial cells.     

The discovery of polymer‐clay hybrids

The first successful example of a polymer‐clay hybrid was nylon‐clay hybrid (NCH), which is a nano‐meter‐sized composite of nylon‐6 and 1‐nm‐thick exfoliated aluminosilicate layers of the clay mineral. NCH was found and developed at Toyota Central Research and Development Laboratories over 17 years ago. The NCH containing a few weight percentages of clay exhibits superior properties such as high modulus, high strength, and good gas‐barrier properties. The key for the discovery of NCH was the polymerization of a nylon monomer in the interlayer space of the clay. This highlight presents the development of NCH from its discovery to its commercialization. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 819–824, 2004     

A novel boron-rich quaternary scandium borocarbosilicide Sc3.67−xB41.4−y−zC0.67+zSi0.33−w

A novel quaternary scandium borocarbosilicide Sc_3.67−xB_41.4−y−zC_0.67+zSi_0.33−w was found. Single crystallites were obtained as an intergrowth phase in the float-zoned single crystal of Sc_0.83−xB_10.0−yC_0.17+ySi_0.083−z that has a face-centered cubic crystal structure. Single crystal structure analysis revealed that the compound has a hexagonal structure with lattice constants a = b = 1.43055(8) nm and c = 2.37477(13) nm and space group (No. 187). The crystal composition calculated from the structure analysis for the crystal with x = 0.52, y = 1.42, z = 1.17, and w = 0.02 was ScB_12.3C_0.58Si_0.10 and that agreed rather well with the composition of ScB_11.5C_0.61Si_0.04 measured by EPMA. In the crystal structure that is a new structure type of boron-rich borides, there are 79 structurally independent atomic sites, 69 boron and/or carbon sites, two silicon sites and eight scandium sites. Boron and carbon form seven structurally independent B₁₂ icosahedra, one B₉ polyhedron, one B₁₀ polyhedron, one irregularly shaped B₁₆ polyhedron in which only 10.7 boron atoms are available because of partial occupancies and 10 bridging sites. All polyhedron units and bridging site atoms interconnect each other forming a three-dimensional boron framework structure. Sc atoms reside in the open spaces in the boron framework structure.     

An Infrared Spectroscopic Study on the Hofmann-diam-type 1,12-Diaminododecanemetal(II) Tetracyanonickelate(II)-aromatic Guest Clathrates: M(H2N(CH2)12NH2)Ni(CN)4ċG(M=Co, Ni or Cd; G = Benzene, Naphthalene, Anthracene, Phenanthrene or Biphenyl)

Three Hofmann-diaminododecane-type clathrates of the form M(1,12-diaminododecane) Ni(CN)₄G (M = Co, Ni or Cd; G = benzene, naphthalene, anthracene, phenanthrene or biphenyl) have been prepared in powder form. The 1,12-diaminododecane molecules in the host lattice permit the inclusion of bulky guest molecules. The spectral features suggest that these compounds are similar in structure to the other Hofmann-diam-type clathrates.     

Naphthalene Complexation by β-Cyclodextrin: Influence of Added Short Chain Branched and Linear Alcohols

Naphthalene forms 1 : 1 complexes with 12j2xn30410130g/xxlarge946.gif" alt="beta" align="MIDDLE" BORDER="0">-cyclodextrin (12j2xn30410130g/xxlarge946.gif" alt="beta" align="MIDDLE" BORDER="0">-CD)in water. The binding constant is 377 ± 35 M^-1. Addition of linear or branched alcohols causes a reduction in the apparent strength of naphthalene binding (K_app) compared to the value in the absence of additives. For example, 1% 1-pentanol reduces K_app to 184 ± 31 M^-1. Branching does not alter K_app much for a given number of carbon atoms, e.g., it is 113 ± 9 M^-1for 2-pentanol and 116 ± 8 M^-1for 3-pentanol. The exception to this is tert-butanol for which K_app is 577 ± 40 M^-1. The variation in K_app as a function of [1-pentanol] yields values for the individual equilibrium constants contributing to K_app. This reveals that a ternary complex forms involving naphthalene, the CD and 1-pentanol. The constant for formation of the ternary complex is 99 ± 29 M^-2. NaI quenching of naphthalene fluorescence indicates that the CD cavity partially protects the naphthalene excited state fromthis water phase quencher. Interestingly, the Stern–Volmer constant is lower in the presence of 1-pentanol than in its absence, although there should be more unbound (and therefore more NaI accessible) naphthalene in the former system than in the latter. These apparently contradictory results are discussed in terms of ternary complex formation.     

Extended generalized octagons and the groupHe

Let be an extended generalized octagon such that the points of a triple {u, v, w} not on a block are pairwise adjacent if and only if the distance betweenv andw in the local generalized octagon _u equals 3 and there is a thick line through any point of _u . Then is one of the two examples related to the groups 2·L ₃(4).2² andHe. It is also shown that does not admit further extensions.     

The structure of the core of a numerical contraction

A bounded linear operatorT is a numerical contraction if and only if there exists a selfadjoint contractionZ such that . The aim of the present paper is to study the structure of the coreZ(T) of all selfadjoint contractions satisfying the above inequality. Especially we consider several conditions for thatZ(T) is a single-point set. By using this argument we shall characterize extreme points of the set of all numerical contractions. Moreover we shall give effective sufficient conditions for extreme points.     

A regularity result for critical points of conformally invariant functionals

Let be an open set inR ² andI be a conformally invariant functional defined onH ¹(,R ^d ). Letu be a critical point ofI. We show that, ifu is apriori assumed to be bounded, thenu is smooth in , up to (ifu _| is smooth). This is a partial (positive) answer to a conjecture of S. Hildebrandt [13]. As an application, we establish a regularity result for weak solutions to the equation of surfaces of prescribed mean curvature in a three-dimensional compact riemannian manifold.     

Nets and generalized quadrangles

There is a new method of constructing generalized quadrangles (GQs) given by S. Löwe, which is based on covering of nets; all GQs with a regular point can be represented in this way. Here we give a method of constructing GQs with a regular point using the so-called content functions on nets. In the last part of the paper we lay the foundations for a research project aiming to use the more general notion of 12222219g321/xxlarge8216.gif" alt="lsquo" align="BASELINE" BORDER="0">content12222219g321/xxlarge8217.gif" alt="rsquo" align="BASELINE" BORDER="0"> to classify GQs and maybe to construct new ones.Both authors acknowledge the financial support by CRUI and DAAD in the frame of Programma Vigoni, which made this work possible.     

Nonlinear transformations of the canonical gauss measure on Hilbert space and absolute continuity

The papers of R. Ramer and S. Kusuoka investigate conditions under which the probability measure induced by a nonlinear transformation on abstract Wiener space(12k/xxlarge947.gif" alt="gamma" align="MIDDLE" BORDER="0">,H,B) is absolutely continuous with respect to the abstract Wiener measure12k/xxlarge956.gif" alt="mgr" align="MIDDLE" BORDER="0">. These conditions reveal the importance of the underlying Hilbert spaceH but involve the spaceB in an essential way. The present paper gives conditions solely based onH and takes as its starting point, a nonlinear transformationT=I+F onH. New sufficient conditions for absolute continuity are given which do not seem easily comparable with those of Kusuoka or Ramer but are more general than those of Buckdahn and Enchev. The Ramer-Itô integral occurring in the expression for the Radon-Nikodym derivative is studied in some detail and, in the general context of white noise theory it is shown to be an anticipative stochastic integral which, under a stronger condition on the weak Gateaux derivative of F is directly related to the Ogawa integral.Research supported by the National Science Foundation and the Air Force Office of Scientific Research Grant No. F49620 92 J 0154 and the Army Research Office Grant No. DAAL 03 92 G 0008.