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61.
从大曲酒窖池底泥中分离到一株产己酸量较高的菌株.经初步鉴定,应归于梭状芽抱杆菌属,很可能是克氏梭状芽抱杆菌( Clostridium kluyveri ).其最适生长温度35'C最适pH为7.。左右.最适酵母提取物浓度在生长时为100、产酸时为0.100,乙醇浓度在100-4%范围内对生长和产酸影响不大·在醋酸钠培养基中生长10天,己酸产量最高可达380mg/100m1.这一菌株的获得为白酒增香工艺的研究奠定了基础. 相似文献
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Infrared thermography determines the surface temperature of an object or human body. It is a promising imaging technology for medical and biological observations due to its contactless and completely non- invasive properties. However, traditional two-dimensional (2D) infrared thermography cannot retain the spatial information, and thus provides only qualitative diagnosis information. A novel real-time three- dimensional (3D) infrared imaging system which takes full advantages of high-speed, high-quality, high- sensitivity, and low-cost in 3D thermograph is presented. We demonstrate the real-time 3D thermal imaging at the speed of 24 frmnes per second (fps), with resolution of 640 ×480 points. Experimental results demonstrate quantitatively measurement of temperature distribution of 3D surfaces in real-time is realized with this system. 相似文献
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高质量实验教材是本科实验教学的重要保证,在创新型人才的培养中发挥着巨大的作用。本文从编写背景、指导思想、项目编写与修订等方面介绍了化学生物学综合实验教材的建设情况。该教材经历了十多年实验教学的考验,能较好满足相关学科的学生培养需要。 相似文献
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不同剂量重离子辐照玉米自交系的生物学效应比较 总被引:2,自引:0,他引:2
用12C6+和 36Ar18+离子束分别辐照玉米自交系干种子和浸泡种子, 研究了M1—M3代重离子束辐照的生物学效应。 结果表明: 种子发芽势和发芽率随辐照剂量的增加而下降, 不同生理状态的种子对重离子辐照的敏感性也不同。 一般12C6+ 离子辐照干种子的适宜剂量为20—25 Gy; M1代叶型发生明显的变化, M2代植株在株高、穗位、单株穗数、雄穗花药颜色、粒质、穗行数、粒重和抗性等方面均发生了变化, 并产生了许多有益的变异,包括株高和穗位降低、同位多穗、穗行数和粒重增加、粒质由粉质变为硬粒以及抗锈病和红叶病的植株等, 有益突变的频率达7.0%—17.9%;在M3代出现能够稳定遗传的,并且光合效率增加的有益突变株。由此可见,重离子束辐照是玉米种质改良的一种高效手段。 In order to study biological effects of heavy ion irradiation on maize inbred lines, the agronomic traits and photosynthetic rates were investigated from M1 to M3 of maize seeds irradiated with 12C6+ and 36Ar18+ ions.The results showed that the germination rate and planting percent of maize seeds irradiated were decrease as dosage increasing of heavy ion irradiation. Different physiological status of seeds had disparate sensibility to heavy-ion irradiation and the suitable dosage of 12C6+ ion irradiation was 20—25 Gy for dry maize seeds. The leaf type of the plant happened visible changes in M1 generation. The plant height, spike position, spike number per plant, anther color of staminate,grain texture,spike row,grain weight and resistance had changes in M2 generation. Among them occurred some beneficial mutations that include degrading of plant height and spike position height, multi spike at same position in the plant, increasing of pike row and grain change of grain texture from powder seed to hard seed,resistance to rust disease and red leaf disease and so on. The frequency of beneficial mutation was 7.0%—17.9%. Those beneficial mutations could be stably inherited and mutant plants with high photosynthetic efficiency emerged in M3 generation. The study above showed that heavy ion irradiation is a high performance means for improvement germplasm of maize. 相似文献
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O-连接β-N-乙酰葡糖胺(O-GlcNAc)糖基化是广泛存在于蛋白质丝/苏氨酸残基的翻译后修饰.这一动态、可逆单糖修饰以位点特异性方式影响底物蛋白的结构和生物学功能,参与调控几乎所有细胞生理过程和重大疾病的演进过程.随着研究深入,O-GlcNAc糖基化生物功能的系统解析需要更多特异、精准的研究工具和糖蛋白质组学研究策略.近年来,化学生物学领域开发了包括小分子糖探针、生物正交糖代谢标记物、化学酶法、特异性抗体和凝集素等多种O-GlcNAc糖基化分析工具和方法,以此为基础进一步发展了O-GlcNAc糖蛋白质组学研究策略.同时,借助高分辨质谱,大量蛋白质O-GlcNAc修饰位点得以鉴定,极大促进了位点特异性O-GlcNAc的生物功能研究.本文综述了近年来这一领域的研究进展,以期为更多化学工具的开发提供依据,为揭示O-GlcNAc糖基化在疾病演进中的功能提供新的研究思路和策略. 相似文献
69.
A novel chemosensor 1 (CS1) bearing one coumarin and two carbodithioate groups was synthesized and its fluorescent sensing behavior toward metal ions was investigated. Ag^+ addition to a CH3COCH3/H2O (3:7, v:v) solution of CS1 gave a significantly quenched fluorescence. Other ions including Pb^2+, Zn^2+, Cu^2+, Ca^2+, Cd^2+, Co^2+, Mg^2+, Mn^2+, Hg^2+, Ag^+, Ni^2+ induced no or much smaller spectral changes. This constitutes an ON-OFF Ag^+-selective fluorescent chemosensor. 相似文献
70.
Synthesis and biological evaluation of novel thalidomide analogues as potential anticancer drugs 总被引:1,自引:1,他引:0
In search of novel anticancer agents, a series of thalidomide analogs (6a-j) were designed and synthesized. Cytotoxicity of these compounds against human hepatoma cells (HepG2) was evaluated by MTT method. Compounds 6d, 6h and 6i showed significant cytotoxic activities comparable to or stronger than control 5-fluorouracil. 相似文献