海平面会突然升降吗

<正>地球每10万年左右出现一次冰河期,这时海平面会下降100多米。8万年前地球的最近一次冰河期开始了,之后几千年中海平面不断下降,越来越多的水固化为各地的冰川。但是根据美国爱荷华大     

中青年慢性乙型肝炎伴焦虑抑郁患者的心理护理

乙型肝炎是临床上的一种常见病，发病率高，目前尚不能治愈，且具有传染性，往往给患者带来很大的社会和心理压力。尤其是中青年患者，容易产生焦虑抑郁的情绪，严重威胁健康，需要医护人员的关心和帮助。2011-04-12本科对58例中青年慢性乙肝患者加强心理护理，效果较好，现报道如下。     

能监控患者呼气中二氧化碳含量的纳米传感器

美国Nanomix公司研制成能以高精度检测周围空气和患者呼气中二氧化碳含量的纳米传感器，装置不仅体积小、灵敏度高，而且测量准确度高，非常适合用来诊断疾病，例如给火灾中烧伤患者提供救护和在外科手术中进行监控。     

小儿营养不良患者微量元素变化与中医辩证分型关系的探讨

对115例小儿营养不良患者．经测试头发微量元素含量的变化，发现中医不同的辩证分型中，徽量元素的缺乏或偏高各有不同的变化，提示在治疗上，除辩证外，可选择应用某微量元素含量高的同类中药进行治疗，能提高临床疗效．     

葡萄膜炎患者外周血单核细胞表达的疾病相关细胞因子的检测

用ELISA测IL-12、IFN—γ水平；用原位杂交染色法测IL—12 mRNA表达；电泳迁移率改变试验(EM—SA)测NF—AT活性。结果表明：葡萄膜炎患者PBMCIL—12、IFN—γ水平和IL—12m RNA表达以及NF—AT活性都显著高于正常对照和其他眼疾病患者(P＜0．01)．IL—12、IFN—γ水平异常增高是葡萄膜炎患者Th1／Th2功能紊乱、Th1细胞功能亢进主要原因之一；而在转录水平上NF—AT活性异常增高可能与患者IFN—γ基因转录增强密切相关。     

男性型秃发患者与健康人发中微量元素锌,铜,铁和锰含量的测定

本文采用火焰原子吸收法对３０例男性型秃发患者及３８例毛发健康男性对照者头发中微量元素锌、铜、铁和锰的含量进行了测定。本文为开展男性型秃发的病因学和治疗学研究提供了有益的资料。     

Magnetic nanoparticle-based cancer nanodiagnostics

Diagnosis facilitates the discovery of an impending disease. A complete and accurate treatment of cancer depends heavily on its early medical diagnosis. Cancer, one of the most fatal diseases world-wide, consistently affects a larger number of patients each year. Magnetism, a physical property arising from the motion of electrical charges, which causes attraction and repulsion between objects and does not involve radiation, has been under intense investigation for several years. Magnetic materials show great promise in the application of image contrast enhancement to accurately image and diagnose cancer. Chelating gadolinium (Gd Ⅲ) and magnetic nanoparticles (MNPs) have the prospect to pave the way for diagnosis, operative management, and adjuvant therapy of different kinds of cancers. The potential of MNP-based magnetic resonance (MR) contrast agents (CAs) now makes it possible to image portions of a tumor in parts of the body that would be unclear with the conventional magnetic resonance imaging (MRI). Multiple functionalities like variety of targeting ligands and image contrast enhancement have recently been added to the MNPs. Keeping aside the additional complexities in synthetic steps, costs, more convoluted behavior, and effects in-vivo, multifunctional MNPs still face great regulatory hurdles before clinical availability for cancer patients. The trade-off between additional functionality and complexity is a subject of ongoing debate. The recent progress regarding the types, design, synthesis, morphology, characterization, modification, and the in-vivo and in-vitro uses of different MRI contrast agents, including MNPs, to diagnose cancer will be the focus of this review. As our knowledge of MNPs' characteristics and applications expands, their role in the future management of cancer patients will become very important. Current hurdles are also discussed, along with future prospects of MNPs as the savior of cancer victims.     

N-乙酰半胱氨酸对老年患者碘海醇肾损害的保护作用

目的探讨N-乙酰半胱氨酸对老年患者碘海醇肾损害的保护作用。方法选取行增强CT检查（静脉注射碘造影剂碘海醇）的老年患者74例,其中A组26例（于造影前48h和造影后48h口服N-乙酰半胱氨酸600mg,2次/d）,B组25例（于造影前48h和造影后48h口服N-乙酰半胱氨酸600mg,1次/d）;对照组23例（于造影前48h和造影后48h口服安慰剂,1次/d）。造影前和造影后48h,检测3组患者血尿素氮（BUN）、SCr、内生肌酐清除率（CCr）,并记录对比剂肾病发生率,造影前和造影后48h以及5d时,检测24h尿蛋白（PRO）、24h尿β2-微球蛋白(β2- MG)、24h尿微量白蛋白（UmAlb）。结果 A组无CIN发生,B组发生CIN5例（20%）,C发生CIN6例（26.09%）,A组CIN发生率明显低于B、C组（均P＜0.05）。3组患者造影前各指标的差异均无统计学意义（P＞0.05）。与造影前比较,3组患者造影后48h BUN、SCr、Ccr均发生明显变化（P＜0.05）;与B组、对照组比较,A组造影后48h BUN、SCr、Ccr均发生明显变化（P＜0.05）。与造影前比较,3组患者造影后48h、5d时PRO、Umalb、和β2- MG均发生明显变化（P＜0.05）;与对照组比较,A组造影后48h及5d、B组造影后48h的PRO、Umalb、和β2- MG均发生明显变化（P＜0.05）。结论口服N-乙酰半胱氨酸600mg（2次/d）能有效预防老年患者碘海醇肾损害。     

经导管射频消融肾去交感神经术对顽固性高血压疗效的荟萃分析

全球高血压患者超过10亿人,约62%的脑血管疾病和49%的缺血性心脏病与高血压有关[1]。20%-30%的高血压患者为顽固性高血压[2]。自主神经系统活性状态在高血压起病及维持过程中有非常重要的作用[3]。近年来,有学者应用经导管射频消融技术,实施肾脏去交感神经治疗顽固性高血压[4-6],结果安全有效。但该技术应用时间短,单个研究例数少且分散,随访时间短,为了解其降压疗效等情况,我们进行了相关的荟萃分析,现报道如下。