双重敏感mPEG-PDPA-P(AAm-co-AN)聚合物自组装体的药物递送

设计合成了一种新型两亲性三嵌段ABC聚合物聚乙二醇单甲醚-聚甲基丙烯酸二异丙胺基乙酯-聚(丙烯酰胺-co-丙烯腈)(mPEG-PDPA-P(AAm-co-AN))。该聚合物具有pH敏感嵌段PDPA和温度敏感嵌段P(AAm-co-AN)，临界溶解温度(UCST)较高，且可以通过改变单体比例来调节UCST。在室温、中性环境下，该聚合物通过自组装形成刺激响应型胶束，可用于抗肿瘤药物的控释研究。温度升高诱导聚合物胶束向不对称囊泡结构转变，pH降低促使聚合物形成更加松散的胶束。在体外释药探究中，聚合物胶束对亲水药物阿霉素(DOX)和疏水药物槲皮素都具有良好的载药效果，在37℃、pH=7.4的条件下泄漏量低，随着温度升高和pH降低，胶束释放药物的速率和释放量明显增加。     

Stochastic Resonance in an Asymmetric Bistable System Subject to Frequency Mixing Periodic Force and Noise

The phenomenon of stochastic resonance (SR) in an asymmetric bistable system subject to the multiplicative and additive white noises and two periodic fields is investigated. Using the two-state theory, analytic expressions of the signal-to-noise ratio (SNR) for fundamental harmonics and higher harmonics are derived. It is found that SR appears at both fundamental harmonics and mixed harmonics (of second- and third-order approximation).Moreover, the higher the order of mixed harmonics is, the larger the SNR values are. The effects of static asymmetry on the SNR (of second- and third-order approximation) are different, and the noise intensity ratio can enhance the SNR for higher harmonics.     

Comparative Characterization of InGaN/GaN Multiple Quantum Wells by Transmission Electron Microscopy, X-Ray Diffraction and Rutherford Backscattering

The composition, elastic strain and structural defects of InCaN/CaN multiple quantum wells （MQWs） are comparatively investigated by using x-ray diffraction （XRD）, transmission electron microscopy and Rutherford backscattering/channelling. The InGaN well layers are fully strained on CaN, i.e. the degree of relaxation is zero. The multilayered structure has a clear defined periodic thickness and abrupt interfaces. The In composition is deduced by XRD simulation. We show how the periodic structure, the In composition, the strain status and the crystalline quality of the InGaN/GaN MQ, Ws can be determined and cross-checked by various techniques.     

邻硝基苯基荧光酮-Tween 80双波长分光光度法测定微量铝

本文研究了在非离子表面活性剂Tween 80存在下Al(Ⅲ)与O-NPF显色反应的条件,在pH9.0～11.0的HBO_3-Na_2CO_3缓冲溶液中可形成稳定的紫色络合物,最大吸收波长为564nm,铝量在0～5μg/25ml范围符合比尔定律,采用双波长法摩尔吸光系数高达1.81×10~5。本法具有简便、快速、灵敏度高、准确性好等优点。     

An型扭双指标代数

给出了(ふ)(Δ)-有限的An型偏序集的扭双指标代数的完全分类.     

一个基于Keeping Up with the Joneses的随机内生增长模型

本文建立了一个基于Keeping up with the Joneses的随机内生增长模型,利用"伪双状态变量"法得到了均衡时的最优消费、最优经济增长率和最优福利,讨论了相对消费对它们的影响.     

广义弱群像代数

本文首先介绍了广义弱群像代数的概念, 并构造了一系列具体的例子, 通过例子可以看出有限群胚代数和群像代数都可以看作是广义弱群像代数; 接着本文证明了广义弱群像代数也可以看作是一类广义弱双Frobenius代数, 并探讨了广义弱双Frobenius代数成为有限群胚代数的条件; 最后本文给出了低维广义弱群像代数的具体结构.     

振动系统的电模拟演示

介绍了力学振动中的电模拟演示原理。