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121.
ExistenceandUniquenessoftheSolutionofNonlinearPopulationEvolutionEquationsLiHongyi(李红裔)(Dept.ofBasicScience,NorthChinaInstitu...  相似文献   
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The compositional distribution within aggregates of a given size is essential to the functionality of composite aggregates that are usually enlarged by rapid Brownian coagulation. There is no analytical solution for the process of such two-component systems. Monte Carlo method is an effective numerical approach for two-component coagulation. In this paper, the differentially weighted Monte Carlo method is used to investigate two-component Brownian coagulation, respectively, in the continuum regime, the free-molecular regime and the transition regime. It is found that (1) for Brownian coagulation in the continuum regime and in the free-molecular regime, the mono-variate compositional distribution, i.e., the number density distribution function of one component amount (in the form of volume of the component in aggregates) satisfies self-preserving form the same as particle size distribution in mono-component Brownian coagulation; (2) however, for Brownian coagulation in the transition regime the mono-variate compositional distribution cannot reach self-similarity; and (3) the bivariate compositional distribution, i.e., the combined number density distribution function of two component amounts in the three regimes satisfies a semi self-preserving form. Moreover, other new features inherent to aggregative mixing are also demonstrated; e.g., the degree of mixing between components, which is largely controlled by the initial compositional mass fraction, improves as aggregate size increases.  相似文献   
124.
A discrete-time model for an age-structured population in a patch-type environment is presented and analyzed. Comparison techniques for difference equations are used to find sufficient conditions for population persistence or extinction. The persistence and extinction theorem is used to define the critical patch number, the threshold for population persistence. Several examples are presented which illustrate the results of the theorems. The model is applied to a watersnake population.  相似文献   
125.
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In this paper, we consider a single species model with nonlocal dispersalstrategy and discuss how the dispersal rate and the distribution of resources affectthe total population and survival chances by summarizing some previous results anddemonstrate some relevant progress. The first topic is about the monotonicity of totalpopulation upon dispersal rate. For the nonlocal model, we prove a new result, whichreveals essential difference between local and nonlocal models for certain distributionof resources. Secondly, we discuss optimal spatial arrangement for survival chancesand total populations. The results for both local and nonlocal models demonstrate thatthe concentration of resources is beneficial for species.  相似文献   
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Dexmedetomidine is an important sedative agent administered as premedication to achieve procedural sedation in children. To describe the correlation between the genetic state and the concentration of dexmedetomidine, it is necessary to develop a specific, time‐saving and economical method for detection of dexmedetomidine in plasma samples. In this work, an ultra‐high‐performance liquid chromatography (UHPLC)–tandem mass spectrometry method has been established and validated for detection of dexmedetomidine in plasma from pediatric population. After a simple liquid–liquid extraction with an organic solution, the analytes were separated on an ACQUITY BEH C18 column (2.1 mm × 50 mm, 1.7 μm particle size) by gradient elution with the mobile phase of acetonitrile and 1‰ aqueous formic acid (flow rate 0.3 mL min?1). Mass spectrometry measurements were performed under the positive selected reaction monitoring and the mass transitions monitored were m/z 201.3 → 95.1, 204.2 → 98.0 for dexmedetomidine and deuterated medetomidine (internal standard), respectively. Validation of the method based on China Food and Drug Administration guidelines showed acceptable selectivity. The UHPLC method employed a stable isotope‐labeled internal standard, showed good specificity and was successfully used to detect dexmedetomidine in plasma samples from 260 pediatric patients. A subsequent application of this method to a pharmacogenetic study was also described. Importantly, this is the first study to report the correlation between CYP2A6 rs835309 activity and concentration of dexmedetomidine.  相似文献   
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This work is focused on the development and validation of a model accounting for the impact of the reactor residence time distribution in well‐stirred slurry‐phase catalytic polymerization of ethylene. Particle growth and morphology are described through the Multigrain model, adopting a two‐site model for the catalyst and a conventional kinetic scheme. Particle size distribution and polymer properties (average molecular weights and polydispersity) are computed as a function of particle size through a segregated model, assuming that neither breakage nor aggregation occur. Reactors are modeled by means of fundamental mass conservation equations. The model is applied to a system constituted by a series of two ideal continuous stirred tank reactors, where the synthesis of polyethylene with bimodal molecular weight distribution is performed, employing the initial catalyst size distribution as the only adjustable parameter. The model provides insights at the single particle scale for each specific size, thus highlighting the inhomogeneity which arises from the synergic effects of chemical kinetics and residence time distributions in both reactors. The satisfactory agreement between model results and experimental data, in terms of particle size distribution and average molecular weights, confirmed the suitability of the model and underlying assumptions.  相似文献   
129.
    
Population genetics is a scientific discipline that has extensively benefitted from mathematical modelling; since the Hardy‐Weinberg law (1908) to date, many mathematical models have been designed to describe the genotype frequencies evolution in a population. Existing models differ in adopted hypothesis on evolutionary forces (such as, for example, mutation, selection, and migration) acting in the population. Mathematical analysis of population genetics models help to understand if the genetic population admits an equilibrium, ie, genotype frequencies that will not change over time. Nevertheless, the existence of an equilibrium is only an aspect of a more complex issue concerning the conditions that would allow or prevent populations to reach the equilibrium. This latter matter, much more complex, has been only partially investigated in population genetics studies. We here propose a new mathematical model to analyse the genotype frequencies distribution in a population over time and under two major evolutionary forces, namely, mutation and selection; the model allows for both infinite and finite populations. In this paper, we present our model and we analyse its convergence properties to the equilibrium genotype frequency; we also derive conditions allowing convergence. Moreover, we show that our model is a generalisation of the Hardy‐Weinberg law and of subsequent models that allow for selection or mutation. Some examples of applications are reported at the end of the paper, and the code that simulates our model is available online at https://www.ding.unisannio.it/persone/docenti/del-vecchio for free use and testing.  相似文献   
130.
    
In this paper, a method to accelerate population transfer by designing nonadiabatic evolution paths is proposed. We apply the method to realize robust and accelerated population transfer with a transmon qutrit. By numerical simulation, we show that this method allows a robust population transfer between the ground states in a Λ system. Moreover, the total pulse area for the population transfer is low as 1.9π that verifies the evolution is accelerated without increasing the pulse intensity. Therefore, the method is easily implementable based on the modern pulse shaper technology and it provides selectable schemes with interesting applications in quantum information processing.  相似文献   
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