Three stochastic sensors based on nanodiamond (nDP) paste modified with α, β, and γ‐cyclodextrin were designed and characterized for pattern recognition of aspartame, acesulfame K and sodium cyclamate in beverages, ketchup, and biological fluids. The linear concentration ranges obtained for acesulfame K (between 1.00×10?10 mol L?1and 1.00×10?3 mol L?1), for aspartame (between 1.00×10?12 mol L?1 and 1.00×10?3 mol L?1) and for sodium cyclamate (between 4.97×10?12 mol L?1 and 4.97×10?3 mol L?1) allow their assay in biological fluids, beverages and ketchup. The lowest limits of quantification were obtained using the stochastic sensor based on γ‐CD/nDP: for acesulfame K 1.00×10?10 mol L?1, for aspartame 1.00×10?12 mol L?1 and for sodium cyclamate 4.97×10?12 mol L?1. All three stochastic sensors revealed very high values of sensitivities. The proposed method was reliable for qualitative and quantitative assay of aspartame, acesulfame K and sodium cyclamate in beverages, ketchup, and in biological fluids such as urine. 相似文献
Metal–organic frameworks (MOFs) with long‐term stability and reversible high water uptake properties can be ideal candidates for water harvesting and indoor humidity control. Now, a mesoporous and highly stable MOF, BIT‐66 is presented that has indoor humidity control capability and a photocatalytic bacteriostatic effect. BIT‐66 (V3(O)3(H2O)(BTB)2), possesses prominent moisture tunability in the range of 45–60 % RH and a water uptake and working capacity of 71 and 55 wt %, respectively, showing good recyclability and excellent performance in water adsorption–desorption cycles. Importantly, this MOF demonstrates a unique photocatalytic bacteriostatic behavior under visible light, which can effectively ameliorate the bacteria and/or mold breeding problem in water adsorbing materials. 相似文献
Anabolic androgenic steroids are widely abused substances in sports doping. Their detection present limitations regarding the use of soft ion sources such as electrospray or atmospheric pressure chemical ionization by liquid chromatography–tandem mass spectrometry. In the current study, a novel derivatization method was developed for the ionization enhancement of selected anabolic androgenic steroids. The proposed method aims at the introduction of an easily ionizable moiety into the steroid molecule by converting the hydroxyl groups into imidazole carbamates using 1,1′‐carbonyldiimidazole as derivatization reagent. The proposed method was applied to water and urine samples spiked with exogenous anabolic androgenic steroids in various concentration levels. Steroid imidazole carbamate derivatives have shown intensive [M+H]+ signals under electrospray ionization and common fragmentation patterns in tandem mass spectrometry mode with [M‐CO2+H]+ and [M‐ΙmCO2+H]+ as major ions with low collision energy. The obtained results showed that the majority of steroids were detectable at concentrations equal or lower to their minimum required performance level according to the World Anti‐Doping Agency technical document. The proposed method is sensitive with a preparation procedure that could be easily applied to the analysis of doping control samples. 相似文献
The wavelet multiresolution interpolation for continuous functions defined on a finite interval is developed in this study by using a simple alternative of transformation matrix. The wavelet multiresolution interpolation Galerkin method that applies this interpolation to represent the unknown function and nonlinear terms independently is proposed to solve the boundary value problems with the mixed Dirichlet-Robin boundary conditions and various nonlinearities, including transcendental ones, in which the discretization process is as simple as that in solving linear problems, and only common two-term connection coefficients are needed. All matrices are independent of unknown node values and lead to high efficiency in the calculation of the residual and Jacobian matrices needed in Newton’s method, which does not require numerical integration in the resulting nonlinear discrete system. The validity of the proposed method is examined through several nonlinear problems with interior or boundary layers. The results demonstrate that the proposed wavelet method shows excellent accuracy and stability against nonuniform grids, and high resolution of localized steep gradients can be achieved by using local refined multiresolution grids. In addition, Newton’s method converges rapidly in solving the nonlinear discrete system created by the proposed wavelet method, including the initial guess far from real solutions.
Objective: To clarify the effect of intervention with dynamic motor control exercise (DMCE) for the lumbar region on low back pain in sedentary office workers (SOWs). Methods: The participants comprised 32 SOWs with low back pain who were randomly categorized into two groups: the DMCE group and the normal trunk exercise (NTE) group. Both groups performed each exercise for three days per week for 8 weeks. The primary endpoints were evaluated for the lumbar and hip flexion angles during trunk forward bending, effect of low back pain on activities of daily living (using the Oswestry Disability Index), and intensity of low back pain (using the Visual Analog Scale) pre- and post-intervention. The extent of changes was calculated by subtracting the pre-intervention value from the post-intervention value and was compared between the two groups using an unpaired t-test. Results: The extent of changes in the lumbar flexion and hip flexion angles at 10° of trunk forward bending were significantly greater in the DMCE group than in the NTE group, and no significant differences were noted between the two groups at other angles of trunk forward bending. The extent of changes in the Oswestry Disability Index and the Visual Analog Scale scores were significantly greater in the DMCE group than in the NTE group. Conclusion: DMCE is effective in improving motor control in the lumbar region and hip joints, thereby ameliorating low back pain in SOWs. 相似文献