地方政府竞争、重复建设及其规制政策分析

分权体制下地方政府竞争引发的重复建设和产业同构问题影响了区域经济的协调发展。本文构建了地方政府投资博弈的重复建设模型,并在此基础上探讨使地方政府行为从产业竞争转向合作的激励机制和制度安排。研究发现:在中国垂直的政治管理体制下,中央政府实施对高利润行业征税或者对低利润行业补贴或者两者并举的政策,可以降低重复建设率,且两者并举的双重激励制度效果最优。这些制度安排在保持地方政府发展经济积极性的同时,约束地方政府竞争行为,有利于区域产业体系的完善和区域经济的和谐发展。     

A Differential R&D Game: Implications for Knowledge-Based Growth Models

This paper compares the outcomes of strategic and nonstrategic research and development (R&D). Firms undertake cost-reducing R&D in an environment where benefits accrue from their rivals' R&D via a common pool of knowledge. We demonstrate that multiple suboptimal equilibria exist; under these conditions, growth models which do not consider strategic interactions will overestimate or underestimate the growth rate.     

Using components of mathematical ability for initial development and identification of mathematically promising students

Kruteskii's work on the mathematical abilities of school children is a seminal work on the nature of mathematical ability. However, the task of developing methods for the practical application of his work is still a significant problem in mathematics education. The authors have developed a practical application of Kruteskii's approach to the important problem of initially developing components of mathematical ability in student and thereafter identifying mathematically promising students. Examples of problems that were designed to develop ability to generalize, flexibility and reversibility of mental processes are presented. A practical guide for determining the level of development of components of mathematical abilities in individual students, in terms of specified observables, is presented as a set of structured reference tables. The authors set out a practical application protocol that combines use of the tables and sets of specially developed problems for initial development of mathematical abilities prior to identification of mathematically promising students in the general classroom. A significant motivation for this work is the desire to avoid time-consuming and resource intensive practices such as interviews and summer schools which therefore have been used successfully because these practices are now out of reach for all but very wealthy countries or highly ideologically driven systems. On the other hand, special examinations heavily depend on the level of preparedness of the students for the particular examination, and therefore some students with high abilities but with fewer opportunities to prepare could be overlooked.     

含氟β-氨基酸及其衍生物的合成进展

含氟β-氨基酸及其衍生物具有特殊的生理活性, 其合成方法的研究近年来受到广泛关注. 以直接氟化法和间接氟化法分类, 概述了含氟β-氨基酸及其衍生物的合成方法及最新研究进展, 对一些已知化合物的生理活性及药用价值作了初步归纳.     

Development of new and robust LC-MS method for simultaneous quantification of polyphenols from Sambucus ebulus fruits

A new and simple LC-MS method for analysis of flavonoids from Sambucus ebulus berry extracts was developed and validated. Successfully were quantitated seven polyphenols: epicatechin, epigallocatechin gallate, rutin, resveratrol, myricetin, quercetin, and kaempferol.

Two detectors, working in parallel, were used: photodiode-array and single quadrupole mass-detector. The mass detection was used for identification and quantification of the analytes, while the diode-array detector was as confirmation tool. The following m/z were tracked: 457.15 (epigallocatechin gallate); 289.06 (epicatechin); 609.13 (rutin); 227.05 (resveratrol); 317.0 (myricetin); 301.02 (quercetin); 285.02 (kaempferol). For optimization the chromatographic separation three wavelengths 205?nm, 305?nm, 272?nm were monitored. The method was capable to detect in one run compounds with no UV or fluorescence chromophore and with very similar structures, such as plant polyphenols. The linearity was from 0.05?mg/L to 50?mg/L (R² 0.9962–0.9987). The recoveries for all tested analytes were between 81.6% and 104.7%.

The method was applied for analysis of crude extract of Sambucus ebulus ripe fruits. Three major polyphenols – epicatechin (0.84?mg/100gFW), quercetin (0.15?mg/100gFW) and kaempferol (0.05?mg/100gFW) were identified and quantified.

The proposed method could be successfully used for routine analysis of epigallocatechin gallate, epicatechin, rutin, resveratrol, myricetin, quercetin, and kaempferol in Sambucus ebulus extracts.     

边疆的“地方”格局与“世界”意义—四十年来中国边疆对外开放的理路与目标

改革开放以来,中国陆地边疆省区的对外开放经历了三个阶段：最初,边疆省区的对外开放呈现出“对内开放”的形态,边疆省区远离沿海的地理劣势被无限放大,本土知识社会精英对边疆对外开放的历史地位进行反思,提出“双向发展”的理论观点;随后,中央政府发布了沿边开放战略,边疆省区地方政府和社会知识精英充分认识到本地区在对外开放中的优势,从理论和实践两个层面验证边疆已由对外开放的“袋底”变为“袋口”;进入新时代,边疆省区在推动地方经济社会发展之外,还服务于周边外交。四十年间,边疆作为中国的“地方”,“发展”一直是边疆对外开放的基本目标。进入新时代,作为中国与“世界”联系的前沿,边疆对外开放已被赋予构筑“人类命运共同体”的崇高使命。     

Degradation-fragmentation of marine plastic waste and their environmental implications: A critical review

This review critically evaluates the plastic accumulation challenges and their environmental (primarily) and human (secondarily) impacts. It also emphasizes on their degradation and fragmentation phenomena under marine conditions. In addition, it takes into account the leachability of the various chemical substances (additives) embedded in plastic products to improve their polymeric properties and extend their life. Regardless of their effectiveness in enhancing the polymeric function of plastic products, these additives can potentially contaminate air, soil, food, and water. Several findings have shown that, regardless of their types and sizes, plastics can be degraded and/or fragmented under marine conditions. Therefore, the estimation of fragmentation and degradation rates via a reliable developed model is required to better understand the marine environmental status. The main parameter, which is responsible for initiating the fragmentation of plastics, is sunlight/UV radiation. Yet, UV- radiation alone is not enough to fragment some plastic polymer types under marine conditions, additional factors are needed such as mechanical abrasion. It should be also mentioned that most current studies on plastic degradation and fragmentation centered on the primary stages of degradation. Thus, further studies are needed to better understand these phenomena and to identify their fate and environmental effects.     

Development and validation of high-performance liquid chromatography method for analysis of β-CCT and its related substances

Compound 2β-carbomethoxy-3β-(4-chlorophenyl)tropane (β-CCT) is a key intermediate for the synthesis of some clinical dopamine transporter (DAT) imaging agents. Potential impurities from synthesis process of β-CCT and degradation during storage might have detrimental effect on the final imaging agents. Thus, it is necessary to guarantee the quality of β-CCT. In this study, a rapid, sensitive and accurate high-performance liquid chromatography (HPLC) method was developed and validated for the analysis of β-CCT and its related substances. The chromatographic separation was achieved on a reverse-phase phenomenex? Gemini C18 column with an isocratic mobile phase consisted of methanol, water and TFA (30:70:0.1 v/v/v). The flow rate was 1.0 mL/min at 30 °C and samples were monitored at 220 nm. The method was validated concerning system suitability, linearity, accuracy, precision, specificity, robustness and stability. The limit of detection (LOD) and the limit of quantification (LOQ) of β-CCT were 0.5 and 1.5 μg/mL, respectively. The linearity range of β-CCT was 1.5–450 μg/mL with a good linear correlation coefficient (R² = 0.9999) between the peak response and concentration. Specificity investigation through forced degradation experiments displayed that β-CCT was stable in acidic, thermal and photolytic degradation conditions, but significantly unstable in alkaline and oxidative conditions. With the developed chromatographic method, possible impurity α-CCT from synthetic process and potential degradation products could be well separated from β-CCT. Good recovery and precision were manifested in the assay method. These results indicated that the present method would be suitable for not only the quality assurance of β-CCT in regular production sample assays but also the monitoring and determination of its related substances.     

化学类拔尖学生培养与高校青年教师成长协同发展实践*

在高等教育大众化的背景下,通过教学改革培养高素质的拔尖人才已显得非常重要。介绍一种以新入职的青年教师为实施主体的“理论课助教+实验课教学+科研训练”相结合的教学形式。通过连续、跟踪式的教学,不但可以选拔、培养出拔尖的化学类本科生,而且能够促进新入职的青年教师快速成长进步,起到“教学相长”的作用。     

在传承与发展中加强化学基础实验课程体系建设

实验教学在化学学科人才培养体系中发挥着重要作用,吉林大学化学学科已历70年的发展,在传承“厚基础、强能力、重实践”的教学传统的同时,顺应时代发展,构建了新的“两阶段、三层次”的基础实验教学体系,融入新的教学内容。在先进的育人理念指导下,构建了满足个性化和差异化教学的多层次基础实验课程体系,全方位提升学生实验能力和综合素养。