巴盟乌拉特后旗地方性甲状腺肿患病率调查及防治

对乌拉特后旗１４９１０名居民进行了地方性甲状腺肿患病率调查，患病率为５．９４％，属于轻病区。地方性甲状腺肿的患病率在性别和年龄间均存在着显著性差异，男性患病的高峰年龄是１０岁，女性患病的高峰年龄是１５岁－和３０岁－。甲状腺肿大的类型主为弥漫型，占９０．７４％。对患者口服磺化钾治疗，总有效率为９０．９１％。     

包头市青山区8～10岁儿童碘缺乏病甲状腺肿大率及尿碘监测分析

调查了内蒙古青山区８～１０岁儿童碘缺乏病甲状腺肿大率，结果表明，甲状腺肿大率为１９．６％，且以城乡结合部居住儿童为高，监测了其尿碘，尿碘水平１００μｇ／Ｌ以下者为１１．２％，其中５０μｇ／Ｌ者了有发现，据此情况，今后仍要强化防治工作。     

Recent insights into iron homeostasis and their application in graminaceous crops

Higher plants utilize various mechanisms to maintain iron homeostasis. To acquire sparingly soluble iron from the rhizosphere, graminaceous plants synthesize natural iron (III) chelators known as mugineic acid family phytosiderophores (MAs). Recent research has uncovered various genes involved in iron uptake and translocation, as well as factors regulating the expression of these genes, especially in rice. Manipulation of these molecular components is used to produce transgenic crops with enhanced tolerance to iron deficiency, or with a high seed iron content. Since iron homeostasis is closely linked to that of other mineral elements, an understanding of this phenomenon will serve as the basis for the production of crops with low concentrations of toxic metals and transgenic plants for phytoremediation.     

与顶点A-划分有关的上可嵌入图类

图G的顶点A-划分是指:G的顶点集划分{V1,V2,···,Vs},其中G[Vi](1≤i≤s)为多重完全图或多重完全二部图.文中结合图的顶点A-划分,顶点度及边连通性等条件确定了一些新的上可嵌入图类,从而将已有类似结果进行了推广,且完整地刻画了这类图的上可嵌入性情况.     

带有辅助信息的ROC曲线两种估计的比较

在医学研究中,常常使用受试者操作特性曲线(ROC)曲线来研究两样本的比较问题。Lloyd构造了ROC曲线的核平滑估计,并给出了其渐近偏差以及渐近标准差。此外,当还可以获悉某一处理组上的辅助信息时,Zhou,Zhou & Ma利用经验似然的方法构造了ROC曲线的核平滑经验似然估计。本文利用"亏量"这个概念比较了带有辅助信息的情况下,对核平滑经验似然估计与完全经验似然估计进行了比较。并给出了核平滑经验似然估计优于完全经验似然估计的结论,并且随着样本容量的增大,该亏量也是无限增大的。     

具有中间亏指数的线性哈密顿算子的点谱

本文讨论具有任意亏指数d的自伴线性哈密顿算子点谱与对应的线性哈密顿系统的平方可积解之间的关系.若对于某个实开区间中的任意点λ,系统总有d个线性无关解,则它的任何自伴算子的点谱在这个开区间上是不稠密的.     

[Nb@Ge13/14]3−: New Family Members of Ge-Based Intermetalloid Clusters

During the past two decades, single-atom-centered medium-sized germanium clusters [M@Ge_n] (M=transition metals, n>12) have been extensively explored, both from theoretical perspectives and experimental gas-phase syntheses. However, the actual structural arrangements of the Ge₁₃ and Ge₁₄ endohedral cages are still ambiguous and have long remained an unresolved problem for experimental implementation. In this work, we successfully synthesize 13-/14-vertex Ge clusters [Nb@Ge₁₃]³⁻ ( 1 ) and [Nb@Ge₁₄]³⁻ ( 2 ), which are structurally characterized and exhibit unprecedented topologies, neither classical deltahedra nor 3-connected polyhedral structures. Theoretical analysis indicates that the major stabilization of the Ge backbones arises due to the substantial interaction of Ge 4p-AOs with the endohedral Nb 4d-AOs through three/four-center two-electron bonds with an enhanced electron density accumulated over the shortest Nb−Ge13 contact in 1 . Low occupancies of the direct two-center two-electron (2c–2e) Nb−Ge and Ge−Ge σ bonds point to a considerable degree of electron delocalization over the Ge cages revealing their electron deficiency.     

The anti-HIV potential of imidazole,oxazole and thiazole hybrids: A mini-review

Human immunodeficiency virus (HIV) especially HIV-1 infection and its progression to acquired immune deficiency syndrome (AIDS) remains a significant global health challenge. The advent of the highly active antiretroviral therapy (HAART) has greatly extended the life expectancy of patients living with HIV, but it has become evident that long-term HAART will not eliminate the HIV reservoir and cure the infection. Moreover, the drug resistance and undesirable side effects hamper efficacious therapy, creating an urgent need to develop novel, more effective and less toxic anti-HIV therapeutics. Imidazole, oxazole and thiazole with two heteroatoms at meta-position of five-membered rings are fascinating structures and constitute an important class of heterocycles in drug discovery. Their derivatives could exert the anti-HIV activity through diverse mechanisms and possess promising antiviral activity against both drug-sensitive and drug-resistant HIV strains. This review summarizes the research progress made regarding the anti-HIV potential of imidazole, oxazole and thiazole hybrids, and the structure–activity relationships (SARs) are also discussed to facilitate further rational design of more effective candidates, covering articles published from 2012 to 2022.