极化3He系统核磁共振FID信号的激光探测

极化率测量装置是极化³He系统的重要组成部分之一.本文介绍了一套在极化³He系统上搭建的激光探测自由感应衰减核磁共振（FID NMR）信号的实验装置,该装置有望为³He极化率的高精度实时测量提供新的途径.激光探测法的原理是法拉第旋光效应,该方法使用一束线偏振光探测极化³He磁矩绕主磁场进动的FID信号,实验结果表明相较于拾波线圈探测方法,激光探测方法的信噪比提高了106%,对³He的极化率测量更精确.该探测方法有望替代传统的拾波线圈,广泛地应用于³He极化系统的极化率测量或精密测量实验中.     

发光二极管在几个电磁学实验中的应用

采用发光二极管对电磁感应现象、自感现象、互感现象和电磁振荡等演示实验进行了改进,明显地提高了实验效果．     

磁感应强度B与F-P标准具自由光谱范围的关系

以Hg的546．1nm谱线为例,讨论塞曼效应实验中磁感应强度B与F—P标准具自由光谱范围的关系。     

Analytical model development of an eddy-current-based non-contacting steel plate conveyance system

A concise model for analyzing and predicting the quasi-static electromagnetic characteristics of an eddy-current-based non-contacting steel plate conveyance system has been developed. Confirmed by three-dimensional (3-D) finite element analysis (FEA), adequacy of the analytical model can be demonstrated. Such an effective approach, which can be conveniently used by the potential industries for preliminary system operational performance evaluations, will be essential for designers and on-site engineers.     

束缚电荷特性的实验演示

电介质表面在极化过程中产生束缚电荷,束缚电荷与自由电荷有明显的区别,通过一系列的实验,演示了束缚电荷既不能离开电介质,也不能在电介质中自由移动,也就是“束缚”的特性。     

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采用射频(RF)等离子体对颗粒形状不规则的钨粉球化,研究了加料速率和钨粉分散方式对球化率的影响。通过用电子扫描显微镜(SEM)观测得到的被球化粉末的百分比评估了球化效率。通过对球化处理的钨粉的X射线衍射谱(XRD)的检测,验证了在球化过程中无氧化发生和其它杂质介入。当钨粉以极短暂时间(约几毫秒)快速穿越等离子体炬时,钨粉颗粒因受热而熔化成液滴,快速冷却后,形成致密的球形固态颗粒。     

利用霍尔效应测磁场实验的数据处理

推导了亥姆霍兹线圈产生磁场的全空间分布的普遍公式,讨论了如何确定磁感应强度的方向。就实验内容进行了实例分析,利用Matlab软件进行了相关计算,提出了利用霍尔效应测磁场实验的数据处理方法。最后,详细讨论了亥姆霍兹线圈所在平面处磁场强度相关参数的分布曲线。     

Comparison of the Nucleation Kinetics Obtained from the Cumulative Distributions of the Metastable Zone Width and Induction Time Data

A linearized integral model based on classical nucleation theory is applied in this work to determine the interfacial energy and pre-exponential factor using a linear plot from the cumulative distributions of the metastable zone width (MSZW) data for some systems reported in the literature, including isonicotinamide, butyl paraben, dicyandiamide, and salicylic acid. Based on the same criterion for the nucleation point, the interfacial energy and pre-exponential factor are determined using the conventional linear regression method from the cumulative distributions of the induction time data for the same systems. The results indicate that the interfacial energy and pre-exponential factor calculated from the MSZW data are consistent with those calculated from the induction time for the studied systems.     

Targeting Akt/NF-κB/p53 Pathway and Apoptosis Inducing Potential of 1,2-Benzenedicarboxylic Acid,Bis (2-Methyl Propyl) Ester Isolated from Onosma bracteata Wall. against Human Osteosarcoma (MG-63) Cells

Onosma bracteata Wall. is an important medicinal and immunity-enhancing herbs. This plant is commonly used in the preparation of traditional Ayurvedic drugs to treat numerous diseases. Inspired by the medicinal properties of this plant, the present study aimed to investigate the antiproliferative potential and the primary molecular mechanisms of the apoptotic induction against human osteosarcoma (MG-63) cells. Among all the fractions isolated from O. bracteata, ethyl acetate fraction (Obea) showed good antioxidant activity in superoxide radical scavenging assay and lipid peroxidation assay with an EC₅₀ value of 95.12 and 80.67 µg/mL, respectively. Silica gel column chromatography of ethyl acetate (Obea) fraction of O. bracteata yielded a pure compound, which was characterized by NMR, FTIR, and HR-MS analysis and was identified as 1,2-benzene dicarboxylic acid, bis (2-methyl propyl) ester (BDCe fraction). BDCe fraction was evaluated for the antiproliferative potential against human osteosarcoma MG-63, human neuroblastoma IMR-32, and human lung carcinoma A549 cell lines by MTT assay and exhibited GI₅₀ values of 37.53 μM, 56.05 μM, and 47.12 μM, respectively. In MG-63 cells, the BDCe fraction increased the level of ROS and simultaneously decreased the mitochondria membrane potential (MMP) potential by arresting cells at the G₀/G₁ phase, suggesting the initiation of apoptosis. Western blotting analysis revealed the upregulation of p53, caspase3, and caspase9 while the expressions of p-NF-κB, p-Akt and Bcl-xl were decreased. RT-qPCR studies also showed upregulation in the expression of p53 and caspase3 and downregulation in the expression of CDK2, Bcl-2 and Cyclin E genes. Molecular docking analysis displayed the interaction between BDCe fraction with p53 (−151.13 kcal/mol) and CDK1 (−133.96 kcal/mol). The results of the present work suggest that the BDCe fraction has chemopreventive properties against osteosarcoma (MG-63) cells through the induction of cell cycle arrest and apoptosis via Akt/NF-κB/p53 pathways. This study contributes to the understanding of the utilization of BDCe fraction in osteosarcoma treatment.     

Agarwood—The Fragrant Molecules of a Wounded Tree

Agarwood, popularly known as oudh or gaharu, is a fragrant resinous wood of high commercial value, traded worldwide and primarily used for its distinctive fragrance in incense, perfumes, and medicine. This fragrant wood is created when Aquilaria trees are wounded and infected by fungi, producing resin as a defense mechanism. The depletion of natural agarwood caused by overharvesting amidst increasing demand has caused this fragrant defensive resin of endangered Aquilaria to become a rare and valuable commodity. Given that instances of natural infection are quite low, artificial induction, including biological inoculation, is being conducted to induce agarwood formation. A long-term investigation could unravel insights contributing toward Aquilaria being sustainably cultivated. This review will look at the different methods of induction, including physical, chemical, and biological, and compare the production, yield, and quality of such treatments with naturally formed agarwood. Pharmaceutical properties and medicinal benefits of fragrance-associated compounds such as chromones and terpenoids are also discussed.