Unsupervised cell identification on multidimensional X‐ray fluorescence datasets

A novel approach to locate, identify and refine positions and whole areas of cell structures based on elemental contents measured by X‐ray fluorescence microscopy is introduced. It is shown that, by initializing with only a handful of prototypical cell regions, this approach can obtain consistent identification of whole cells, even when cells are overlapping, without training by explicit annotation. It is robust both to different measurements on the same sample and to different initializations. This effort provides a versatile framework to identify targeted cellular structures from datasets too complex for manual analysis, like most X‐ray fluorescence microscopy data. Possible future extensions are also discussed.     

Preliminary study on CAD-based method of characteristics for neutron transport calculation

Our new method makes use of a CAD-based automatic modeling tool, MCAM, for geometry modeling and ray tracing of particle transport in method of characteristics (MOC). It was found that it could considerably enhance the capability of MOC to deal with more complicated models for neutron transport calculation. In our study, the diamond-difference scheme was applied to MOC to reduce the spatial discretization errors of the flat flux approximation. Based on MCAM and MOC, a new 2D MOC code was developed and integrated into the SuperMC system, which is a Super Multi-function Computational system for neutronics and radiation simulation. The numerical results demonstrated the feasibility and effectiveness of the new method for neutron transport calculation in MOC.     

Effective coefficients of quasi-steady Maxwell’s equations with multiscale isotropic random conductivity

The effective coefficients in the quasi-steady Maxwell’s equations are calculated for a multiscale isotropic medium by using a subgrid modeling approach. The conductivity is mathematically represented by a Kolmogorov multiplicative continuous cascade with a lognormal probability distribution. The scale of the solution domain is assumed to be large as compared with the scale of heterogeneities of the medium. The theoretical results obtained in the paper are compared with the results of a direct 3D numerical simulation and the results of the conventional perturbation theory.     

聚光型粗细调互补阳光信号采集器的研制

高准确度自动跟踪系统是太阳能聚光器必不可少的组成部分,而信号采集器能否精确可靠地采集到阳光照射方向的信号又是自动跟踪准确度的关键.本文提出了一种粗细调互补信号采集器的设计方案,在正常工作期间通过软件能够根据需要不断地自动调整选择二组光电传感器中其中一组输出的差模信号作为有效信号,从而有效地解决了大范围寻找太阳和高准确度跟踪之间的矛盾|而在此基础上改进为对聚光后的阳光信号进行采集的新结构,又彻底解决了光电传感器本身在光照强度很大时进入饱和区与光照强度很弱时输出的差模信号太小的问题,有效延长了聚光器在早晚时段的正常工作时间.据此原理制作的聚光型粗细调互补信号采集器应用于某公司的CPV型1200W砷化镓发电系统中,取得了很好的跟踪效果,其实际跟踪误差≤0.1°（立体角）.     

基于Matlab Simulink的物理实验——简谐振动仿真研究

以简谐振动和阻尼振动仿真为例介绍了用Simulink对物理实验进行仿真建模的方法。给出了位移、速度等振动曲线;可对振动过程中的动能、势能以及机械能进行监测。体现出Simulink仿真物理实验的优越性。     

Interaction of diethyl aniline methylphosphonate with DNA: Spectroscopic and isothermal titration calorimetry

In this study the diethyl aniline methylphosphonate (DAM) was synthesized, the interaction of DAM with ct-DNA has been investigated by fluorescence spectra, UV spectra, molecular modeling and isothermal titration calorimetry (ITC). The binding constant of DAM to ct-DNA calculated from both isothermal titration calorimetry and fluorescence spectra were found to be in the 10⁴ M⁻¹ range. According to the ethidium bromide displacement studies, UV spectra and isothermal titration calorimetry experimental results, it can be concluded that DAM is an intercalator that can slide into the G-C rich region of ct-DNA. Furthermore, the results obtained from molecular modeling corroborated the experimental results obtanied from spectroscopic and ITC investigations. At the same time, fluorescence spectra suggested that the mechanism of the interaction of DAM to ct-DNA was a static enhancing type. ITC data showed that ct-DNA/DAM binding is enthalpy controlled.     

飞行器气动参数辨识进展

飞行器气动参数辨识研究的主题,是应用系统辨识技术从飞行试验数据求取气动力,从而建立飞行器动力学系统的数学模型.它研究的对象是飞行器;解决的是空气动力学问题;采用的基本方程是飞行动力学的运动方程组;应用的研究手段是现代控制论的滤波、预测和估计理论.它是处于空气动力学、飞行力学、弹性力学和现代控制论之间的应用性研究课题. 本文综述了国内外公开发表的飞行器参数辨识研究的理论结果和实践经验,分八个专题——模型辨识,参数估计,数据预处理和相容性检验,试验设计与最佳输入,弹性与非定常效应,频域辨识,闭环辨识,辨识准度与系统验证——评述其研究进展和现状.      

网格模型PDE曲面重建中的边界曲线构造

利用偏微分方程(PDE)进行曲面拟合是计算机图形学研究领域中的常用方法,该类方法通过选取适当的边界条件来构造PDE,用PDE的解来表示几何曲面.基于网格简化方法和离散曲面测地线计算等技术,提出一种从网格模型提取PDE曲面片边界条件曲线的方法.首先,对复杂模型进行简化并分片处理;通过计算离散曲面的测地线为每个分片定义相应的PDE边界条件曲线,进而构造复杂模型的PDE拟合表面.最后,通过细分方法建立原模型的多分辨率表示.实验表明,该方法可以对具有不同几何复杂度的网格模型进行处理,产生具有细分连通性的多分辨网格模型.     

面向对象建模语言AML的设计与实现

ＡＭＬ语言吸取了Ａｄａ９５ 基本原理和思想,引进它的基本数据类型、语句等设施,对其作更高层次的抽象和扩充．用３ 种有相同名字不同类型的程序包从不同的侧面描述给定模块的模型,提高了系统的完整性和一致性;同时运用二级并发模型和限制设施,详述了系统的并发性和不确定性的描述问题．