反相高效液相色谱法同时测定片剂中的加替沙星与盐酸氨溴索

 A reversed-phase high performance liquid chromatography (HPLC) method was developed, validated, and used for the quantitative determination of gatifloxacin (GA) and ambroxol hydrochloride (AM), from its tablet dosage form. Chromatographic separation was performed on a HiQ Sil C18 column (250 mm×4.6 mm, 5 μm), with a mobile phase comprising of a mixture of 0.01 mol/L potassium dihydrogen orthophosphate buffer and acetonitrile (70∶30, v/v), and pH adjusted to 3 with orthophosphoric acid, at a flow rate of 1 mL/min, with detection at 247 nm. Separation was completed in less than 10 min. As per International Conference on Harmonisation (ICH) guidelines the method was validated for linearity, accuracy, precision, limit of quantitation, limit of detection, and robustness. Linearity of GA was found to be in the range of 10-60 μg/mL and that for AM was found to be 5-30 μg/mL. The correlation coefficients were 0.9996 and 0.9993 for GA and AM respectively. The results of the tablet analysis (n=5) were found to be 99.94% with ±0.25% standard deviation (SD) and 99.98% with±0.36% SD for GA and AM respectively. Percent recovery of GA was found to be 99.92%-100.02% and that of AM was 99.86%-100.16%. The assay experiment shows that the method is free from interference of excipients. This demonstrates that the developed HPLC method is simple, linear, precise, and accurate, and can be conveniently adopted for the routine quality control analysis of the tablet.     

掺Yb3+激光玻璃光谱特性研究

采用高温熔融工艺制备了Yb3 掺杂激光玻璃.测试了玻璃的吸收光谱和发射光谱,计算了Yb3 的积分吸收截面和受激发射截面及荧光寿命等参数.玻璃光谱曲线表明:吸收主峰位于975.35 nm,在900～962 nm范围内有一较为弥散的吸收次峰,中心波长为939.17nm;荧光主峰位于977.15 nm,荧光次峰位于997.42 m;随着样品厚度的增加,荧光次峰强度和荧光主峰强度在增大,荧光次峰波长和荧光主峰波长向长波方向移动;荧光有效线宽从34.64 nm增大到54.50 nm;荧光寿命由1.04 ms减小为1.00 ms.     

Measurement of radiative gas and particle emissions in biomass flames

Radiation is the dominant mode of heat transfer near the burner of coal and biomass-fired boilers. Predicting and measuring heat transfer is critical to the design and operation of new boiler concepts. The individual contributions of gas and particle phases are dependent on gas and particle concentration, particle size, and gas and particle temperature which vary with location relative to the flame. A method for measuring the contributions of both gas and particle radiation capable of being applied in harsh high temperature and pressure environments has been demonstrated using emission from particles and water vapor using an optical fiber probe transmitting a signal to a Fourier Transform Infrared (FTIR) spectrometer. The method was demonstrated in four environments of varying gas and particle loading using natural gas and pulverized wood flames in a down-fired 130?kW_th cylindrical reactor. The method generates a gas and particle temperature, gas concentrations (H₂O and CO₂), total gas and particle intensities, and gas and particle total effective emissivity from line-of-sight emission measurements. For the conditions measured, downstream of the luminous flame zone, water vapor and CO₂ radiation were the dominant modes of heat transfer (effective emissivity 0.13–0.19) with particles making a minor contribution (effective emissivity 0.01–0.02). Within a lean natural gas flame, soot emission was low (effective emissivity 0.02) compared to gas (0.14) but within a luminous flame of burning wood particles (500?µm mean diameter) the particles (soot and burning wood) produced a higher effective emissivity (0.17) than the gas (0.12). The measurement technique was therefore found to be effective for several types of combustion environments.     

Control of bulk and surface radioactivity in bolometric searches for double-beta decay

The problem of background reduction in bolometers used to search for ββ(0ν) is reviewed with particular emphasis on bulk and surface radioactive contamination of the detectors.     

Investigation of the influence of inner-shell photoionization and photoexcitation on the Heα spectrum in photoionized plasmas

The present paper investigates the influence of inner shell photoionization and photoexcitation on the He_α, i.e., the 1s² to 1s2p transition in He-like ions, and the associated satellite spectra in photoionized plasmas. A comparison of the importance of these processes is made relative to other atomic processes as a function of the electron temperature and irradiation conditions. For the formation of the He_α and the satellite spectra, the K-shell photoionization is found to have significant contribution under low radiation temperature and/or intensity, when lithium- and beryllium-like ions have high abundance, but highly ionized H-like ions are rare.     

Regular wave integral approach to numerical simulation of radiation and diffraction of surface waves

A regular wave integral method is developed in the discretisation of a linear hydrodynamic problem on radiation and diffraction of surface waves by a floating or submerged body. The velocity potential of the problem is expressed as a solution of a body boundary integral equation involving the pulsating free surface Green function or pulsating free surface sources distributed on the body surface. With the use of a discretisation on the regular wave integral rather than discretisations on the singular wave integral of the Green function as in earlier investigations, the singular wave integral is approximated as an expansion of regular (or nonirregular) wave potentials. Influence coefficients between pulsating free surface source points are computed by the approximate expansion together with Hess–Smith panel integral formulas. Thus the velocity potential solution is evaluated by a boundary element algorithm. The numerical results produced from the proposed method agree well with semi-analytic solution results.     

北仑水厂实时自动投药系统的建模与研究

运用统计分析建立了可用于水处理投药过程中控制投药量的数学模型,分析了混凝药剂、沉淀池水中的浊物量差值等参数对水处理投药量的影响,拟合出滤前浊度小于1.3NTU的数学模型.用所建立的投药量数学模型投药结果得到的出厂水水质比人工经验投加得到的水质稳定性高,而且耗药率低.     

Orbital dynamics in the photogravitational restricted four-body problem: Lagrange configuration

We study the effect of the radiation parameter in the location, stability and orbital dynamics in the Lagrange configuration of the restricted four-body problem when one of the primaries is a radiating body. The equations of motion for the test particle are derived by assuming that the primaries revolve in the same plane with uniform angular velocity, lying at the vertices of an equilateral triangle. The insertion of the radiation factor in the restricted four-body problem, let us model the dynamics of a test particle orbiting an astrophysical system with an active star. The dynamical mechanisms responsible for the smoothening on the basin structures of the configuration space is related to the decrease in the total number of fixed points with increasing values of the radiation parameter. In our model of the Sun-Jupiter-Trojan Asteroid system, it is found that despite the solar radiation pressure, there exist two stable libration points.     

基于听觉特性的舰船辐射噪声信号仿真

针对工程应用中对舰船辐射噪声信号仿真结果在听觉感受上模拟度欠佳的问题,建立了一种基于音色参量谱质心的辐射噪声仿真方法。采用基于实测谱的连续谱仿真模拟,并且通过整体对比实测信号的听觉特性来搜索符合特征样本音色的线谱族幅值参量,在一定程度上改善了仿真信号的听觉特征。通过仿真最优匹配度趋势来寻求最优搜索次数,用以缩短仿真时间,得到了符合工程应用的结果。     

Dy3+ doped SiO2–B2O3–Al2O3–NaF–ZnF2 glasses: An exploration of optical and gamma radiation shielding features

A series of Dy³⁺ doped zinc-aluminoborosilicate glasses with chemical composition 30SiO₂-(30-x) B₂O₃–10Al₂O₃–15NaF–15ZnF₂-xDy₂O₃ (x = 0, 0.5, 0.7, 1.0 and 1.5 mol %) were prepared by conventional melt-quenching method. Structural and optical properties of the glasses were analyzed through XRD, FTIR, UV–Visible–NIR and luminescence studies. Gamma radiation shielding parameters were obtained using PSD software. Nephelauxetic ratio (β) and bonding parameters (δ) calculated using absorption spectrum shows the decreasing ionic nature of the Dy ions. Judd-Oflet parameters (Ω₂, Ω₄ and Ω₆) obtained shows the covalency and asymmetric nature of dysprosium ions. The luminescence properties shows that Dy³⁺ doped glasses have two strong intense emission at blue (482 nm) and yellow (575 nm) region. Branching ratio and stimulated emission cross section calculated suggests the glasses suitability to act as lasing material. CIE colour coordinates and its colour correlated temperature (CCT) for the glasses were estimated and found that these prepared glasses lie in the warm white light region.