Analysis of alkaloids in Macleaya cordata (Willd.) R. Br. using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry

A method for the analysis of alkaloids in Macleaya cordata (Willd.) R. Br. using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry (HPLC-DAD-ESI/MS) was developed. Using protopine (PRO), allocryptopine (ALL), sanguinarine (SA), and chelerythrine (CHE) as the model components, different columns for the separation and different mobile phases for the signal intensities of alkaloids in ESI/MS were investigated, respectively. The results showed that good separation and high signal intensities can be obtained on a high carbon loading (17%) reversed-phase C(18) column with 30 mM formic acid in mobile phase for the analysis of alkaloids. Under the optimal separation condition and UV detection (284 nm), linearity of the six alkaloids was obtained over concentration range from 0.05 to 100.00 microg/ml. The limit of detection (LOD) was 1.62, 1.87, 1.79, 1.76, 1.10, and 0.94 ng/ml for SA, CHE, PRO, ALL, dihydrosanguinarine (DHSA), and dihydrochelerythrine (DHCHE), respectively. The LODs with ESI/MS detection were lower three orders of magnitude than those obtained with UV detection. The proposed method could be used to control quality of the raw materials of the herb more comprehensively.     

Theoretical studies on the infrared spectrum of the tetrahedral molecules R<Subscript>2</Subscript>MH<Subscript>2</Subscript> (R = D(H), CH<Subscript>3</Subscript>, OH; M = Ti,Zr, Hf)

Using Stuttgart/Dresden effective core potentials MWB28, MWB60, and GTO valence basis sets (8s7p6d)/[6s5p3d], (8s7p6d)/[6s5p3d] for Zr and Hf atoms and 6-311++G(3df,3pd) basis set for C, H, O, and Ti atoms, tight convergence criteria geometry optimizations and harmonic frequency calculations are performed at B3LYP and B3LYP/IEF-PCM levels of theory so as to model the gas phase and argon matrix infrared spectra of the tetrahedral molecules R₂MH₂ (R = D(H), CH₃, OH; M = Ti, Zr, Hf). Influence of the transition metal and/or substituent group on the symmetric and asymmetric stretching frequencies of the MH₂ fragment of the R₂MH₂ molecules is investigated at both the levels of theory. The modelling of the argon matrix effect improves the agreement between the calculated frequencies and the experimental ones. The calculated argon matrix to gas phase frequency shifts is compared reasonably to the experimental argon to neon matrix shifts.     

Stability and Evolution of Synonyms and Homonyms in Signaling Game

Synonyms and homonyms appear in all natural languages. We analyze their evolution within the framework of the signaling game. Agents in our model use reinforcement learning, where probabilities of selection of a communicated word or of its interpretation depend on weights equal to the number of accumulated successful communications. When the probabilities increase linearly with weights, synonyms appear to be very stable and homonyms decline relatively fast. Such behavior seems to be at odds with linguistic observations. A better agreement is obtained when probabilities increase faster than linearly with weights. Our results may suggest that a certain positive feedback, the so-called Metcalfe’s Law, possibly drives some linguistic processes. Evolution of synonyms and homonyms in our model can be approximately described using a certain nonlinear urn model.     

R600a／矿物冷冻油混合物表面张力

本文利用新改进的表面张力实验系统对R600a／矿物冷冻油混合物的表面张力进行了实验研究,其中R600a的质量分数分别为O．95、0．90和0．85,温度范围为253．15-333．15K。实验结果表明,随着含油量的增加,R600a／矿物冷冻油的表面张力逐渐减小,矿物油的存在对纯质制冷剂的表面张力有比较明显的影响。     

Viscosity Effects on Anisotropic Universe in Curvature-Matter Coupling Gravity

In this paper, we study evolution of the universe in the background of f(R, T) gravity using LRS Bianchi type-Ⅰ model. We discuss scale factors as well as deceleration parameter in dark energy dominated era for different bulk viscosity models. The occurrence of big-rip singularity is also examined. It is concluded that expansion is faster when bulk viscosity is proportional to Hubble parameter as compared to other models.     

Dijkgraaf–Witten invariants of surfaces and projective representations of groups

We compute the Dijkgraaf–Witten invariants of surfaces in terms of projective representations of groups. As an application we prove that the complex Dijkgraaf–Witten invariants of surfaces of positive genus are positive integers.     

一种新的基于缺陷的软件测试描述语言-DBSTDL

在软件测试领域,缺乏统一的测试描述语言(TDL)已成为提高测试效率和复用程度的瓶颈。区别以设备、信号等为核心的传统测试语言,设计的测试描述语言(DBSTDL)面向软件缺陷,围绕软件缺陷与被测软件信息双重主线,设计了6类词, 3大类100多条基本语句, 3组句群, 2种主要的语言组合方式。应用DBSTDL语言实现了软件典型缺陷与测试样例库,验证了利用DBSTDL语言建库的思想。     

R值测量中强子事例选择的改进

强子事例的选择和强子探测效率是在BEPC/BES上进行R值测量的两项主要误差来源. 过去实验只选取等于或者大于2叉的强子事例, 因而0叉和1叉事例的丢失将导致强子事例数和强子探测效率的较大误差. 试图提出在R值测量中选取包含1叉强子事例在内的样本, 这将有助于更合理地调节强子事例产生器LUARLW的参数, 减小强子探测效率和R值测量的系统误差.     

原始数据中束流相关本底的分离

束流相关本底处理的不确定性是在BES/BEPC上进行R值测量的主要误差来源之一,提出从原始数据中分离出束流相关样本的新方法, 并把此样本用于调节强子产生器LUARLW的参数,以减小强子探测效率的系统误差, 提高R值的测量精度.     

钙钛矿锰氧化物La0.7Sr0.3MxMn1-xO3(M=Cr,Fe)的巨磁电阻效应与磁性

研究了溶胶 -凝胶法制备氧化物巨磁电阻材料的工艺 ,制备了La0 .7Sr0 .3 CrxMn1-xO3 (x =0 ,0 .10 ,0 .15 )和La0 .7Sr0 .3 FexMn1-xO3 (x =0 .0 5 ,0 .10 ,0 .16 )两系列的单相钙钛矿锰氧化物多晶样品 ,并研究了Cr ,Fe替代La0 .7Sr0 .3 MnO3 中部分Mn后对其结构、磁性和巨磁电阻性质的影响 .观察到La0 .7Sr0 .3 Cr0 .15Mn0 .85O3 和La0 .7Sr0 .3 Fe0 .0 5Mn0 .95O3 两个样品的电阻 温度曲线都出现了双峰 .定性讨论了可能产生双峰的机制 .随Cr(或Fe)替代量的增加 ,材料的居里温度很快下降 ,铁磁性减弱 ,导电性降低 ,巨磁电阻效应增强 .但与Fe掺杂相比 ,相同数量的Cr掺杂对材料的影响要小 .