This paper describes an experimental investigation of the feasibility of using “slow” active control approaches, which “instantaneously” change liquid fuel spray properties, to suppress combustion instabilities. The objective of this control approach was to break up the feedback between the combustion process heat release and combustor pressure oscillations that drive the instability by changing the characteristics of the combustion process (e.g., the characteristic combustion time). To demonstrate the feasibility of such control, this study used a proprietary fuel injector (NanomiserTM), which can vary its fuel spray properties, to investigate the dependence of acoustics–combustion process coupling, i.e., the driving of combustion instabilities, upon the fuel spray properties. This study showed that by changing the spray characteristics it is possible to significantly damp combustion instabilities. Furthermore, using combustion zone chemiluminescence distributions, which were obtained by Abel’s deconvolution synchronized with measured acoustic data, it has been shown that the instabilities were mostly driven midway between the combustor centerline and wall, a short distance downstream from the flame holder, where the mean axial flow velocity is approximately zero in the vortex near the flame holder. The results of this study strongly suggest that a “slow” active control system that employs controllable fuel injectors could be effectively used to prevent the onset of detrimental combustion instabilities. 相似文献
This paper gives a p-adic analogue of the Mackey theory, which relates representations of a group of type G - H × t A to systems of imprimitivity. 相似文献
Cancer immunotherapy aims at stimulating the immune system to react against cancer stealth capabilities. It consists of repeatedly injecting small doses of a tumor-associated molecule one wants the immune system to recognize, until a consistent immune response directed against the tumor cells is observed.
We have applied the theory of optimal control to the problem of finding the optimal schedule of injections of an immunotherapeutic agent against cancer. The method employed works for a general ODE system and can be applied to find the optimal protocol in a variety of clinical problems where the kinetics of the drug or treatment and its influence on the normal physiologic functions have been described by a mathematical model.
We show that the choice of the cost function has dramatic effects on the kind of solution the optimization algorithm is able to find. This provides evidence that a careful ODE model and optimization schema must be designed by mathematicians and clinicians using their proper different perspectives. 相似文献
The paper is devoted to studying the distribution of stationary solutions for 3D Navier-Stokes equations perturbed by a random force. Under a non-degeneracy assumption, we show that the support of such a distribution coincides with the entire phase space, and its finite-dimensional projections are minorised by a measure possessing an almost surely positive smooth density with respect to the Lebesgue measure. Similar assertions are true for weak solutions of the Cauchy problem with a regular initial function. The results of this paper were announced in the short note [A. Shirikyan, Controllability of three-dimensional Navier-Stokes equations and applications, in: Sémin. Équ. Dériv. Partielles, 2005-2006, École Polytech., Palaiseau, 2006]. 相似文献