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161.
In this paper, we study the Heinz type inequalities for mappings satisfying Poisson’s equation. Some results generalize the ones obtained by Partyka and Sakan.  相似文献   
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We present a Roe‐type weak formulation Riemann solver where the average coefficient matrix is computed numerically. The novelty of this approach is that it is general enough that can be applied to any hyperbolic system while retaining the accuracy of the original Roe solver. We show applications to the compressible Euler equations with general equation of state. An alternative version of the method uses directly the eigenvectors in the averaging process, simplifying the algorithm. These new solvers are applied in conservative and path‐conservative schemes with high‐order accuracy and on unstructured meshes. Copyright © 2014 John Wiley & Sons, Ltd.  相似文献   
165.
The purpose of this paper is to study a new two-step iterative scheme with mean errors of mixed type for two asymptotically nonexpansive self-mappings and two asymptotically nonexpansive nonself-mappin...  相似文献   
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Ⅱ期临床试验的主要目的是对药物治疗的安全性和有效性进行评估.针对具有高安全性的Ⅱ期两阶段临床试验,给出小样本量下关于安全性和有效性的精确检验方法,并证明最大Ⅰ类错误概率与Ⅱ类错误概率分别在原假设和备择假设的边界处达到.在期望样本量最小原则下,给出最优两阶段设计的构造方法和常用设计表,供实际应用选用.  相似文献   
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For a general dyadic grid, we give a Calderón–Zygmund type decomposition, which is the principle fact about the multilinear maximal function on the upper half‐spaces. Using the decomposition, we study the boundedness of . We obtain a natural extension to the multilinear setting of Muckenhoupt's weak‐type characterization. We also partially obtain characterizations of Muckenhoupt's strong‐type inequalities with one weight. Assuming the reverse Hölder's condition, we get a multilinear analogue of Sawyer's two weight theorem. Moreover, we also get Hytönen–Pérez type weighted estimates.  相似文献   
168.
In recent years, there is emerging evidence that isoflavonoids, either dietary or obtained from traditional medicinal plants, could play an important role as a supplementary drug in the management of type 2 diabetes mellitus (T2DM) due to their reported pronounced biological effects in relation to multiple metabolic factors associated with diabetes. Hence, in this regard, we have comprehensively reviewed the potential biological effects of isoflavonoids, particularly biochanin A, genistein, daidzein, glycitein, and formononetin on metabolic disorders and long-term complications induced by T2DM in order to understand whether they can be future candidates as a safe antidiabetic agent. Based on in-depth in vitro and in vivo studies evaluations, isoflavonoids have been found to activate gene expression through the stimulation of peroxisome proliferator-activated receptors (PPARs) (α, γ), modulate carbohydrate metabolism, regulate hyperglycemia, induce dyslipidemia, lessen insulin resistance, and modify adipocyte differentiation and tissue metabolism. Moreover, these natural compounds have also been found to attenuate oxidative stress through the oxidative signaling process and inflammatory mechanism. Hence, isoflavonoids have been envisioned to be able to prevent and slow down the progression of long-term diabetes complications including cardiovascular disease, nephropathy, neuropathy, and retinopathy. Further thoroughgoing investigations in human clinical studies are strongly recommended to obtain the optimum and specific dose and regimen required for supplementation with isoflavonoids and derivatives in diabetic patients.  相似文献   
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