具有遗传性疾病和性状的遗传位点分析

随着信息技术的进步和发展,现代生物学越来越多地将这些技术用于大规模生物数据的收集、分析、挖掘等过程.大量计算机技术,特别是统计方法被用来进行复杂疾病的分析.大量研究表明,人体的许多表型性状差异以及对药物和疾病的易感性等都可能与某些位点相关联,或和包含有多个位点的基因相关联.因此,定位与性状或疾病相关联的位点在染色体或基因中的位置,能帮助研究人员了解性状和一些疾病的遗传机理,也能使人们对致病位点加以干预,防止一些遗传病的发生.利用随机森林方法、Bootstrap重抽样、logistic回归等大数据分析方法,意在解决优化生物学位点关联性分析中单一致病位点识别、多位点相互作用和多性状位点关联性分析等子问题.     

股票市场的长记忆及其动态结构

本文提出了结合平均小波系数法和自回归原始自助法的稳健长记忆检验,蒙特卡罗模拟显示该方法对于短期记忆过程具有稳定性。基于该方法对2005年4月8日至2015年6月30日的中国、美国、香港和德国股市进行了实证分析。全局检验结果表明仅中国的股票市场存在显著的长记忆,并且风险因素无法对长记忆解释,而美国、德国和香港的股市不存在长记忆。基于递增窗口的动态Hurst指数分析显示,金融危机时期4个股市都存在显著的长记忆。2010年后,除中国股市外,其余三个股市几乎不存在长记忆现象。     

On null sequences for Banach operator ideals,trace duality and approximation properties

Let be a Banach operator ideal and X be a Banach space. We undertake the study of the vector space of ‐null sequences of Carl and Stephani on X , , from a unified point of view after we introduce a norm which makes it a Banach space. To give accurate results we consider local versions of the different types of accessibility of Banach operator ideals. We show that in the most common situations, when is right‐accessible for , behaves much alike . When this is the case we give a geometric tensor product representation of . On the other hand, we show an example where the representation fails. Also, via a trace duality formula, we characterize the dual space of . We apply our results to study some problems related with the ‐approximation property giving a trace condition which is used to solve the remaining case () of a problem posed by Kim (2015). Namely, we prove that if a dual space has the ‐approximation property then the space has the ‐approximation property.     

An exact deformation analysis for the magneto-electro-elastic fiber-reinforced thin plate

A closed form expressions for bending problem of magneto-electro-elastic (MEE) rectangular thin plates are derived, the exact solutions for the deformation behaviors of the fiber-reinforced BaTiO₃/CoFe₂O₄ composites subjected to certain types of surface loads are analytically obtained. Based on Kirchhoff thin-plate theory, structural characteristics such as elastic displacements, electric potential and magnetic induction for magneto-electro-elastic (MEE) rectangular plates are investigated, the governing equation in terms of the transverse displacement is presented in a rather compact form due to the omission of the transverse shear deformation and rotatory inertia. The material coefficients for the MEE plate can be uniquely expressed by the volume-fraction (v.f.) of piezoelectric constituent BaTiO₃ in the fiber-reinforced composite, and are tabulated with 25% offset of the volume-fraction. The deformation variations of the MEE thin plate with closed-circuit electric restriction are evaluated analytically according to their specified boundary conditions, and the effects of the volume-fractions on the deformations variations are discussed. It can be found that all the results obtained by using the proposed model have reached good agreements with the other available research works, whereas, the present study provides a much simpler way in seeking the analytic solutions for the interactively coupled quantities of a multiphase medium.     

A unifying theorem for Newton’s method on spaces with a convergence structure

We present a semilocal convergence theorem for Newton’s method (NM) on spaces with a convergence structure. Using our new idea of recurrent functions, we provide a tighter analysis, with weaker hypotheses than before and with the same computational cost as for Argyros (1996, 1997, 1997, 2007) [1], [2], [3] and [5], Meyer (1984, 1987, 1992) [13], [14] and [15]. Numerical examples are provided for solving equations in cases not covered before.     

2×2列联表中二属性相关的Bayes检验

2×2列联表中二属性相关的假设检验是定性数据分析中的热点问题,针对此问题的研究频率学派已做过大量的工作,其理论方法已趋于成熟.利用Bayes检验研究2×2列联表中二属性的相关性迄今为止国内外的相关文献还为数不多.将依据Bayes理论对此问题提出新的检验方法,推出其Bayes因子计算公式,利用正态近似研究三项假设计算出有关的后验概率,不仅解决了频率学派难以处理的问题,并且为吸烟有害健康提供了理论支撑.     

扭转变形平面假设的讨论

在对圆轴扭转平面假设的内涵进行分析的基础上, 关联其在应力分析中 的应用, 并讨论了平面假设成立的条件以解释矩形截面翘曲现象, 可作为该部分课堂教学的 参考材料.     

多元分布下单边备择假设的两步检验

x~2检验是熟知的拟合优度检验.它适用于任意的备择假设,尤其是适用于一般的备择假设"H_0不真"的情况.但是,当备择假设是一个单边假设时,x~2检验没有用到单边假设所提供的信息.因此,一个充分利用单边备择假设信息的检验是有可能优于传统的x~2检验的.本文就是利用单边备择假设的信息给出了一个两步检验,并通过一个例子,详细介绍了两步检验法的实施,说明了其应用.     

非参数假设检验在证券投资分析中的应用

通过引入一种新的估计方法——非参数假设检验方法,以达到对证券投资咨询机构对证券市场大盘走势预测准确度的估计.通过对估计结果的分析得出结论,有99%的把握认为,中国证券市场投资咨询机构所提供的对大盘涨跌的预测,每次有一半家数正确的概率没有达到45%,因而投资者应慎重对待投资咨询机构的大盘预测.