Voltammetric studies on the interactions between camazepam metabolic series and human serum albumin. Determination of oxazepam using adsorptive stripping voltammetry

The behaviour of oxazepam in adsorptive stripping voltammetry was studied taking into account those conditions which have an influence on the accumulation step (electrolyte, pH, time, potential, drop size and stirring rate), rest time and stripping step (pulse amplitude and scan rate). Oxazepam can be determined at a hanging mercury drop electrode by differential-pulse voltammetry in 0.008 M Britton-Robinson buffer at pH 2.0 with a ?0.50 V accumulation potential. Its detection limit was found to be 3.6 × 10^?10 M (30-s accumulation) and the relative standard deviation for oxazepam concentrations in the range 2.8 × 10^?8?4.0 × 10^?7 M is lower than 2.8% (80-s accumulation). In addition, a procedure using adsorptive stripping voltammetry was developed to study the interactions occurring between human albumin and the camazepam metabolic series (camazepam, temazepam and oxazepam). The interactions decreased in the order temazepam ? oxazepam ? camazepam and the groups and structural modifications favouring interaction were determined.     

Differential 3ω calorimeter

We have developed a new dynamic calorimeter using the differential 3ω detection method. The differential 3ω calorimeter is capable of measuring dynamic heat capacity of liquid samples. The new calorimeter consists of a Wheatstone bridge made of two identical heater/sensors, and is based on the sensitive null detection method. The balancing is done automatically at all frequencies and is independent of temperature; once a sample is placed on one heater/sensor, a third harmonic signal is produced due to the difference in the two arms of the bridge. The differential 3ω calorimeter provides enhancements over traditional dynamic methods in dynamic range (up to 30 kHz), resolution, and ease of operation.     

交叉分段差分进化支持向量回归的气体超声 流量计测量方法

为了进一步提高全量程气体超声流量计的测量精度,基于多通道声波到时和实时温度,提出了一种交叉分段差分进化(Differential Evolution)支持向量回归(Support Vector Regression)DE-SVR模型。考虑到气体在不同流量条件下的流体状态不同,提出了交叉分段处理的方法,采用DE算法优化选取SVR参数。实验结果表明,对于16~1600m3/h全量程,交叉分段DE-SVR和传统积分方法计算气体流量的平均相对误差分别为0.00447和0.02781,前者较后者降低了83.93%;对于16~160m3/h小流量,交叉分段DE-SVR和无分段DE-SVR算法计算结果平均相对误差分别为0.00436和0.03214,前者较后者降低了86.43%。该方法有效避免了声道长度、探头角度以及管道直径等参数不确定性对流量计算的影响,为全量程气体流量的高精度测量提供了保障。     

微分求积方法对于桩基大变形分析的应用

本文基于大变形的理论,采用弧坐标首先建立了具有初始位移的桩基的非线性数学模型,一组强非线性的微分-积分方程,其中,地基的抗力采用了Winkeler模型;其次,引入变数变换将微分-积分方程转化为一组非线性微分方程,并用微分求积方法离散了方程组,得到一组离散化的非线性代数方程;最后用Newton-Raphson迭代方法对离散化方程进行了求解,得到了桩基变形前后的构形、弯矩和剪力.计算中选取了两种不同类型的初始位移,并考察了它们对桩基大变形力学行为的影响.     

B原子的掺杂对富勒烯C32的电子传输特性与负微分电阻效应的影响

采用基于密度泛涵理论的第一性原理和非平衡格林函数方法研究了硼原子的掺杂对于富勒稀C32分子的电子传输特性与负微分电阻效应的影响．结果显示硼原子的掺杂明显改变了C32分子的电子传输特性和负微分电阻效应．同时研究了掺杂的硼原子的个数多少对C32分子的影响．     

Counting master integrals: Integration by parts vs. differential reduction

The techniques of integration by parts and differential reduction differ in the counting of master integrals. This is illustrated using as an example the two-loop sunset diagram with on-shell kinematics. A new algebraic relation between the master integrals of the two-loop sunset diagram that does not follow from the standard integration-by-parts technique is found.     

Electrochemical Recognition of Chiral Molecules with Poly(4‐bromoaniline) Modified Gold Electrode

A poly(4‐bromoaniline) (PBA) film is electrochemically synthesized on a gold electrode for the recognition of amino acids enantiomers. Scanning electron microscopy measurements show that the porous PBA films are made up of nano‐ribbons. At the PBA modified Au electrode differential pulse voltammograms of L ‐ and D ‐glutamic acids not only have very different current densities, but also produce different waveforms, providing an intuitive way to differentiate the two chiral molecules. Similar results are obtained in analyzing L ‐ and D ‐aspartic acids. Control experiments suggest that the observed sensing behavior arises from synergistic interactions between Au and the PBA film, where polymerization at the meta‐position creates a steric structure needed for differentiating chiral molecules.     

A Lagrangian for Hamiltonian vector fields on singular Poisson manifolds

On a manifold equipped with a bivector field, we introduce for every Hamiltonian a Lagrangian on paths valued in the cotangent space whose stationary points project onto Hamiltonian vector fields. We show that the remaining components of those stationary points tell whether the bivector field is Poisson or at least defines an integrable distribution—a class of bivector fields generalizing twisted Poisson structures that we study in detail.     

基于多模差分融合的高速车辆定位算法

针对车辆高速运动下定位延时大、精度低、稳定性差的问题,发挥GPS、RSSI和INS三种定位模式的各自优势,将GPS差分校准算法与RSSI测距相结合求解横坐标,将RSSI测距与INS惯导迭代算法相结合求解纵坐标,提出了一种适合高速运动车辆的多模差分融合精确定位算法。以四车道的高速路为场景进行了仿真实验,当车速为70km/h时,跟踪误差<1m,定位延时<0.2s。实验结果表明,该算法可实现车身级和车道级定位,在精确交通诱导、车辆防撞等智能交通领域具有应用前景和推广价值。