首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   76388篇
  免费   8937篇
  国内免费   5906篇
化学   31420篇
晶体学   437篇
力学   5572篇
综合类   1430篇
数学   27285篇
物理学   25087篇
  2024年   112篇
  2023年   623篇
  2022年   1399篇
  2021年   2240篇
  2020年   1747篇
  2019年   1748篇
  2018年   1524篇
  2017年   1937篇
  2016年   2264篇
  2015年   2131篇
  2014年   3196篇
  2013年   5218篇
  2012年   3432篇
  2011年   4070篇
  2010年   3837篇
  2009年   4522篇
  2008年   4931篇
  2007年   5155篇
  2006年   4157篇
  2005年   3357篇
  2004年   3029篇
  2003年   2963篇
  2002年   5314篇
  2001年   2675篇
  2000年   2070篇
  1999年   1855篇
  1998年   1663篇
  1997年   1349篇
  1996年   1333篇
  1995年   1139篇
  1994年   995篇
  1993年   934篇
  1992年   872篇
  1991年   678篇
  1990年   538篇
  1989年   431篇
  1988年   468篇
  1987年   340篇
  1986年   338篇
  1985年   487篇
  1984年   362篇
  1983年   246篇
  1982年   409篇
  1981年   572篇
  1980年   499篇
  1979年   552篇
  1978年   423篇
  1977年   322篇
  1976年   281篇
  1973年   177篇
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
21.
An oriented tetrahedron defined on four vertices is a set of four cyclic triples with the property that any ordered pair of vertices is contained in exactly one of the cyclic triples. A tetrahedral quadruple system of order n with index λ , denoted by TQS λ ( n ) , is a pair ( X , ? ) , where X is an n ‐set and ? is a set of oriented tetrahedra (blocks) such that every cyclic triple on X is contained in exactly λ members of ? . A TQS λ ( n ) is pure if there do not exist two blocks with the same vertex set. When λ = 1 , the spectrum of a pure TQS ( n ) has been completely determined by Ji. In this paper, we show that there exists a pure TQS 2 ( n ) if and only if n 1 , 2 ( mod 3 ) and n 7 . A corollary is that a simple QS 4 ( n ) also exists if and only if n 1 , 2 ( mod 3 ) and n 7 .  相似文献   
22.
Monomeric sarcosine oxidase (mSOx) fusion with the silaffin peptide, R5, designed previously for easy protein production in low resource areas, was used in a biosilification process to form an enzyme layer electrode biosensor. mSOx is a low activity enzyme (10–20 U/mg) requiring high amounts of enzyme to obtain an amperometric biosensor signal, in the clinically useful range <1 mM sarcosine, especially since the Km is >10 mM. An amperometric biosensor model was fitted to experimental data to investigate dynamic range. mSOx constructs were designed with 6H (6×histidine) and R5 (silaffin) peptide tags and compared with native mSOx. Glutaraldehyde (GA) cross‐linked proteins retained ~5 % activity for mSOx and mSOx‐6H and only 0.5 % for mSOx‐R5. In contrast R5 catalysed biosilification on (3‐mercaptopropyl) trimethoxysilane (MPTMS) and tetramethyl orthosilicate (TMOS) particles created a ‘self‐immobilisation’ matrix retaining 40 % and 76 % activity respectively. The TMOS matrix produced a thick layer (>500 μm) on a glassy carbon electrode with a mediated current due to sarcosine in the clinical range for sarcosinemia (0–1 mM). The mSOx‐R5 fusion protein was also used to catalyse biosilification in the presence of creatinase and creatininase, entrapping all three enzymes. A mediated GC enzyme linked current was obtained with dynamic range available for creatinine determination of 0.1–2 mM for an enzyme layer ~800 nm.  相似文献   
23.
24.
This article explores the questions of long time orbital stability in high order Sobolev norms of plane wave solutions to the NLSE in the defocusing case.  相似文献   
25.
Doxorubicin (DOX), a recognized anticancer drug, forms stable associations with carbon nanotubes (CNTs). CNTs when properly functionalized have the ability to anchor directly in cancerous tumors where the release of the drug occurs thanks to the tumor slightly acidic pH. Herein, we study the armchair and zigzag CNTs with Stone–Wales (SW) defects to rank their ability to encapsulate DOX by determining the DOX-CNT binding free energies using the MM/PBSA and MM/GBSA methods implemented in AMBER16. We investigate also the chiral CNTs with haeckelite defects. Each haeckelite defect consists of a pair of square and octagonal rings. The armchair and zigzag CNT with SW defects and chiral nanotubes with haeckelite defects predict DOX-CNT interactions that depend on the length of the nanotube, the number of present defects and nitrogen doping. Chiral nanotubes having two haeckelite defects reveal a clear dependence on the nitrogen content with DOX-CNT interaction forces decreasing in the order 0N > 4N > 8N. These results contribute to a further understanding of drug-nanotube interactions and to the design of new drug delivery systems based on CNTs.  相似文献   
26.
In this paper, we study the global (in time) existence of small data solutions to the Cauchy problem for the semilinear wave equation with friction, viscoelastic damping, and a power nonlinearity. We are interested in the connection between regularity assumptions for the data and the admissible range of exponents p in the power nonlinearity.  相似文献   
27.
According to the one-dimensional quantum state distribution, carrier scattering, and fixed range hopping model, the structural stability and electron transport properties of N-, P-, and As-doped SiC nanowires(N-SiCNWs, P-SiCNWs, and As-SiCNWs) are simulated by using the first principles calculations. The results show that the lattice structure of NSiCNWs is the most stable in the lattice structures of the above three kinds of doped SiCNWs. At room temperature,for unpassivated SiCNWs, the doping effect of P and As are better than that of N. After passivation, the conductivities of all doped SiCNWs increase by approximately two orders of magnitude. The N-SiCNW has the lowest conductivity. In addition, the N-, P-, As-doped SiCNWs before and after passivation have the same conductivity–temperature characteristics,that is, above room temperature, the conductivity values of the doped SiCNWs all increase with temperature increasing.These results contribute to the electronic application of nanodevices.  相似文献   
28.
This paper is dedicated to studying the following Schrödinger–Poisson system Δ u + V ( x ) u K ( x ) ϕ | u | 3 u = a ( x ) f ( u ) , x 3 , Δ ϕ = K ( x ) | u | 5 , x 3 . Under some different assumptions on functions V(x), K(x), a(x) and f(u), by using the variational approach, we establish the existence of positive ground state solutions.  相似文献   
29.
A photo-switchable hetero-complementary quadruple H-bonding array, which consists of an azobenzene-derived ureidopyrimidinone (UPy) module ( Azo-UPy ) and a nonphotoactive diamidonaphthyridine (DAN) derivative ( Napy-1 ), is constructed based on a reversible photo-locking approach. Upon UV (390 nm)/Vis (460 nm) light irradiations, photo-switchable quadruple H-bonded dimerization between Azo-UPy and Napy-1 can be achieved with exhibiting 4.8×104-fold differences in binding strength (ON/OFF ratios). Furthermore, smart polymeric gels with unique photo-controlled macroscopic self-assembly behavior can be fabricated by introducing such quadruple H-bonding array as photo-regulable noncovalent interfacial connections.  相似文献   
30.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号