This paper discusses how gamma irradiation plants are putting the latest advances in computer and information technology to use for better process control, cost savings, and strategic advantages.
Some irradiator operations are gaining significant benefits by integrating computer technology and robotics with real-time information processing, multi-user databases, and communication networks. The paper reports on several irradiation facilities that are making good use of client/server LANs, user-friendly graphics interfaces, supervisory control and data acquisition (SCADA) systems, distributed I/O with real-time sensor devices, trending analysis, real-time product tracking, dynamic product scheduling, and automated dosimetry reading. These plants are lowering costs by fast and reliable reconciliation of dosimetry data, easier validation to GMP requirements, optimizing production flow, and faster release of sterilized products to market.
There is a trend in the manufacturing sector towards total automation using “predictive process control”. Real-time verification of process parameters “on-the-run” allows control parameters to be adjusted appropriately, before the process strays out of limits. Applying this technology to the gamma radiation process, control will be based on monitoring the key parameters such as time, and making adjustments during the process to optimize quality and throughput. Dosimetry results will be used as a quality control measurement rather than as a final monitor for the release of the product. Results are correlated with the irradiation process data to quickly and confidently reconcile variations. Ultimately, a parametric process control system utilizing responsive control, feedback and verification will not only increase productivity and process efficiency, but can also result in operating within tighter dose control set points. 相似文献
In this study, we consider an M/M/c retrial queue with Bernoulli vacation under a single vacation policy. When an arrived customer finds a free server, the customer receives the service immediately; otherwise the customer would enter into an orbit. After the server completes the service, the server may go on a vacation or become idle (waiting for the next arriving, retrying customer). The retrial system is analysed as a quasi-birth-and-death process. The sufficient and necessary condition of system equilibrium is obtained. The formulae for computing the rate matrix and stationary probabilities are derived. The explicit close forms for system performance measures are developed. A cost model is constructed to determine the optimal values of the number of servers, service rate, and vacation rate for minimizing the total expected cost per unit time. Numerical examples are given to demonstrate this optimization approach. The effects of various parameters in the cost model on system performance are investigated. 相似文献
A normalized analytic function f defined on the open unit disk in the complex plane is in the class SL if zf′(z)/f(z) lies in the region bounded by the right-half of the lemniscate of Bernoulli given by ∣w2 − 1∣ < 1. In the present investigation, the SL-radii for certain well-known classes of functions are obtained. Radius problems associated with the left-half plane are also investigated for these classes. 相似文献
Research on nanofluids has progressed rapidly since its enhanced thermal conductivity was first repotted about a decade ago,though much controversy and inconsistency have been reported,and insufficient understanding of the formulation and mechanism of nanofluids further limits their applications.This work presents a critical review of research on heat transfer applications of nanofluids with the aim of identifying the limiting factors so as to push forward their further development. 相似文献
