Selective lighting up of segments around Gly,Ala and Ser/Thr in proteins

Direct detection of ¹³C nucleus can be used as a valuable alternative where ¹H detection poses a challenge due to relaxation effects, chemical exchange and poor chemical shift dispersion. In this context, we have designed a suite of 2D ¹³C^α‐detected hNCA experiments that provide sequential correlations of ¹³C^α with ¹⁵N on one hand and efficient spectroscopic labeling of certain groups of residues, namely, Gly, Ala, Ser and Thr, on the other. These residues act as checkpoints in the sequential walk, which in turn offer new possibilities of backbone assignment of small proteins from a set of 2D experiments, thereby providing great economy in terms of spectrometer time. The direct identification of peptide segments around Gly, Ala, Ser and Thr residues along a protein chain will be highly valuable for deriving important information on sites of ligand binding, phosphorylation, inhibitor/substrate binding, understanding protein folding pathways, comprehending local conformational dynamics etc. without having to obtain complete sequence‐specific assignments, which can be time consuming and at times formidable, especially in large proteins. We have illustratively demonstrated the multifaceted applications of these variants of 2D experiments on ubiquitin and M‐crystallin. We foresee that these 2D hNCA experiments will provide economic and efficient strategies for studying the structure and function of proteins. Copyright © 2012 John Wiley & Sons, Ltd.     

Lie-admissible structures on Witt type algebras

In this paper we study Lie-admissible structures on Witt type algebras. Witt type algebras are Γ$\Gamma$-graded Lie algebras (where Γ$\Gamma$ is an abelian group) which generalize the Witt algebra. We give all third power-associative and flexible Lie-admissible structures on these algebras. In particular we generalize some results on the Witt algebra. After describing the second scalar cohomology group of Witt type algebras, we investigate third power-associative and flexible Lie-admissible structures on the central extension of some Witt type algebras. Finally we study a left-symmetric structure induced by a symplectic form for some Witt type algebras.     

Deformations of Fuchsian Systems of Linear Differential Equations and the Schlesinger System

We consider holomorphic deformations of Fuchsian systems parameterized by the pole loci. It is well known that, in the case when the residue matrices are non-resonant, such a deformation is isomonodromic if and only if the residue matrices satisfy the Schlesinger system with respect to the parameter. Without the non-resonance condition this result fails: there exist non-Schlesinger isomonodromic deformations. In the present article we introduce the class of the so-called isoprincipal deformations of Fuchsian systems. Every isoprincipal deformation is also an isomonodromic one. In general, the class of the isomonodromic deformations is much richer than the class of the isoprincipal deformations, but in the non-resonant case these classes coincide. We prove that a deformation is isoprincipal if and only if the residue matrices satisfy the Schlesinger system. This theorem holds in the general case, without any assumptions on the spectra of the residue matrices of the deformation. An explicit example illustrating isomonodromic deformations, which are neither isoprincipal nor meromorphic with respect to the parameter, is also given.The research of Victor Katsnelson was supported by the Minerva Foundation.     

Ground state rotational spectrum of nitrogen trifluoride: The K = 3 splittings of NF3 and NF3

The ground state rotational spectrum of the ¹⁴NF₃ and ¹⁵NF₃ isotopic species of nitrogen fluoride has been observed in the ∼450-810 GHz frequency range. This investigation allowed us to improve the rotational parameters for both isotopologues. In particular, for the first time the K = 3 line splitting parameter and the sextic centrifugal distortion constants have been determined for ¹⁵NF₃.     

Fermionic stochastic differential equations and the index of Fredholm operators

The index of a Fredholm operator associated to a-summable Fredholm module is expressed in terms of the vacuum expectation value of a unitary operator-valued stochastic process which satisfies a stochastic differential equation with unbounded coefficients driven by fermion noise.     

The algebra of differential operators on the circle and W KP (q)

Radul has recently introduced a map from the Lie algebra of differential operators on the circle of W _n . In this Letter, we extend this map to W _KP ^(q) , a recently introduced one-parameter deformation of W_KP - the second Hamiltonian structure of the KP hierarchy. We use this to give a short proof that W is the algebra of additional symmetries of the KP equation.     

Quasi-classical limit of Toda hierarchy andW-infinity symmetries

Previous results on quasi-classical limit of the KP hierarchy and itsW-infinity symmetries are extended to the Toda hierarchy. The Planck constant now emerges as the spacing unit of difference operators in the Lax formalism. Basic notions, such as dressing operators, Baker-Akhiezer functions, and tau function, are redefined.W _{1 +} symmetries of the Toda hierarchy are realized by suitable rescaling of the Date-Jimbo-Kashiara-Miwa vertex operators. These symmetries are contracted tow _{1 +} symmetries of the dispersionless hierarchy through their action on the tau function.     

The effect of surface modification with silane coupling agent on suppressing the photo-catalytic activity of fine TiO2 particles as inorganic UV filter

The effect of surface modification with 3-aminopropyltriethoxysilane (APTES) and n-propyltriethoxysilane (PTES) on photo-catalytic activity and UV-shielding ability of fine TiO₂ particles were investigated. The number of surface groups (N_R) [nm⁻²] which shows the density of modifier on TiO₂ surface was calculated from the results of elemental analysis and BET measurement. The modified samples of which N_R are different were obtained by changing the concentration of modifier. When the photo-catalytic activity and UV-shielding ability of modified samples were evaluated, it was found that APTES was more effective modifier than PTES to obtained samples with low photo-catalytic activity and high UV-shielding ability. This is probably because the adsorption mechanisms on TiO₂ surface between modifiers were different and N_R is a key factor to control the performances of fine TiO₂ particles. The result of zeta potential showed that surface character of modified samples was varied by changing N_R. It suggested from these results that N_R affected the photo-catalytic activity and UV-shielding ability because N_R changed surface character of modified samples.