蜜蜂外激素9－ODA和9－HDA的合成

６－溴－２－己酮在Ｌｉ２ｃｕＣｌ４催化下与γ－溴代巴豆酸甲酯进行格氏偶联，合成了蜂王物质９－羰基－（Ｅ）－２－癸烯酸（９－ＯＤＡ），将其还原得到另一蜂王物质９－羟基－（Ｅ）－２－癸烯酸（９－ＨＤＡ）。该法是合成９－ＯＤＡ和９－ＨＤＡ的新路线。     

DTA-TG Study of the CaO-SiO2-H2O and CaO-Al2O3-SiO2-H2O Systems Under Hydrothermal Conditions

Simultaneous DTA-TG is an excellent technique for evaluating phases formed in hydrothermally treated CaO-SiO₂-H₂O and CaO-Al₂O₃-SiO₂-H₂O systems. Thermal analysis in combination with XRD and SEM, revealed that in the CaO-Al₂O₃-SiO₂-H₂O system the amount of hydrogarnet formed was the largest when gibbsite was used as the Al source, smallest for kaolin and intermediate for metakaolin. The endotherm peak temperature of the hydrogarnet dehydration endotherm was affected by the amount of hydrogarnet and the Si content of hydrogarnet. The thermal stability and structural order of 11 Å tobermorite were reduced with the incorporation of Al and, as a result, 11 Å tobermorite transformed into 9.3 Å tobermorite at lower temperatures while the transformation of the latter into beta-wollastonite required more energy. There exists a direct relationship between the 9.3 Å tobermorite and beta-wollastonite formation temperatures. Solid-state ²⁹Si and ²⁷Al MAS NMR data support these findings.     

Microcalorimetric Character of Inhibition of Salicylaldehyde Glucosamine Schiff Base SG on Bacterial Metabolism *

ＩｎｔｒｏｄｕｃｔｉｏｎＳｉｎｃｅＳｃｈｉｆｂａｓｅａｎｄｉｔｓｍｅｔａｌｃｏｍｐｌｅｘｅｓａｒｅｏｆａｎｔｉｂａｃｔｅｒｉａｌａｎｄａｎｔｉｃａｎｃｅｒｂｉｏａｃｔｉｖｉｔｉｅｓ,ｔｈｅｙｈａｖｅｂｅｅｎａｒｅｓｅａｒｃｈｓｕｂｊｅｃｔｏｆｍｕｃｈ...     

复方维E霜治疗黄褐斑25例疗效观察

用维生素Ｅ和有机锗配制而成的复方维Ｅ霜治疗黄褐斑２５例，总有效率为８８％。     

11-钨过渡金属杂多阴离子为配体的配合物的热稳定性研究

通式为MW_(11)O_(39)的“不饱和”11-系列杂多阴离子仍然保持了基本的Keggin结构,但失去了其中的一个W-O基团。MW_(11)O_(39)具有很高的反应活性,当其他金属离子(或3A主族元素离子)进入这一空位时,便形成了三元杂多配合物ZMW_(11)和Ln(MW_(11))_2。ZMW_(11)(Z为3A主族金属离子和过渡金属离子)中,11-杂多阴离子起着五齿配体的作用,第六个配位位置被结构水占据,ZMW_(11)基本保持原来的Keggin结构。Ln(MW_(11))_2(Ln为镧系或锕系离子)     

Synthesis and structure of O-(arylcarbamoyl)butyrhydroximoyl chlorides

The O-(arylcarbamoyl)butyrhydroximoyl chlorides were synthesized, and the x-ray structural analysis (XSA) of one of them — O-(o-tolylcarbamoyl)butyrhydroximoyl chloride — was performed. It was established from the data of the XSA and the PMR spectra that all synthesized compounds are the Z isomers.Institute of Physiologically Active Substances, Russian Academy of Sciences, 142432 Chernogolovka. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 2, pp. 315–319, February, 1992.     

大环二萜类化合物的研究(Ⅳ)——Isosarcophytol—A前体化合物的合成

Isosarcophytol-A(1)是1982年首次从澳大利亚软珊瑚(Nephthea brassica)中分离鉴定的西松烷型(Cembrane)大环二萜类化合物,其结构为6,10,14-三甲基-3-异丙基-3E,5E,9E,13E-环十四碳四烯-1-醇,是Sarcophytol—A(2)的异构体,但有关1的生物活性试验和全合成研究尚未见报道.我们在前文报道了以低价钛诱导的分子内二羰基偶联为环化方法,完成了天然大环二萜类化合物Cembrene—C的全合成和Sarcophytol—A(2)苄醚衍生物(3)的合成.本文报道以天然法呢醇4为起始原料,经区域选择性氧化、羟醛缩合等六步反应,合成了1的前体化合物11.合成路线如下: