一种基于C#的XML加密方法的研究与实现

针对在Internet应用中,XML文档传输安全的重要性,研究并提出了一种基于C#.NET环境下XML加密的方案,使用XML加密机制来保证XML信息的安全性。通过研究XML加密的密钥交换方法及基本实现模式,将高级加密算法(AES)与目前广泛应用的公钥算法(RSA)相结合,提出了一种数据安全传输的解     

LC‐MS/MS method for the determination of melamine in rat plasma: Toxicokinetic study in Sprague–Dawley rats

Most recently, melamine has raised international concern for its catastrophic health effects stemming from tainted infant formula. So far there is limited information concerning the pharmacokinetics of melamine in mammals. The present report concerns the development and validation of a sensitive HPLC‐ESI‐MS/MS method for the pharmacokinetic study of melamine in rat. The method employed a simple liquid–liquid extraction process for plasma sample cleanup, and the extraction recoveries of melamine from plasma were consistent at different concentrations. There was a linear relationship between chromatographic area and concentration over the range of 10–5000 ng/mL for melamine in plasma (R = 0.995). In this work, for the first time, melamine was administered intravenously and orally to Sprague–Dawley rats and the pharmacokinetic characteristics of this contaminant were investigated. The mean values of major pharmacokinetic parameters of oral availability, the mean steady‐state distribution volume (V_ss), clearance, and plasma elimination half‐life (T_1/2) of melamine in Sprague–Dawley rats were 72.9 ± 13.2%, 102.5 ± 12.5 mL/kg, 20.1 ± 3.8 mL/h/kg, and 4.9 ± 0.5 h, respectively. The rats pharmacokinetic study results suggested that melamine was predominantly restricted to blood or extracellular fluid and is not extensively distributed to most organ tissues. Meanwhile, melamine should be primarily eliminated by renal filtration for rats and does not undergo significant metabolism. These data should be useful to regulatory for risk assessment.     

高层建筑火灾安全评价的模糊最优归类模型

将模糊数学中的综合评判模型、最优归类模型与高层建筑中对火灾风险有影响的因子相结合，建立了高层建筑火灾风险评价的模糊最优归类模型。并对高层建筑火灾风险评价进行了实例分析。     

Investigations of low <Emphasis Type="Italic">q</Emphasis><Subscript><Emphasis Type="Italic">a</Emphasis></Subscript> discharges in the SINP tokamak

Low edge safety factor discharges including very low q _a (1<q _a <2) and ultra low q _a (0<q _a <1) have been obtained in the SINP tokamak. It has been observed that accessibility of these discharges depends crucially on the fast rate of plasma current rise. Several interesting results in terms of different time scales like T _{q a} · τ _R etc have been obtained using a set of softwares developed at SINP. From fluctuation analysis of the external magnetic probe data it has been found that MHD instabilities m=1, n=1 and m=2, n=1 etc. play major role in the evolution of these discharges. To investigate the internal details of these discharges, an internal magnetic probe system has been developed using which current density j _φ and other related parameters have been estimated. By carrying out a resistive stability analysis, evidence of the above-mentioned MHD instabilities have again been found. The physical processes lying behind the accessibility and evolution of the low q _a discharges have been thoroughly investigated.     

Safety-collision transition induced by lane changing in traffic flow

We study the traffic behavior when a vehicle changes from the first lane to the second lane on a two-lane highway. We apply the optimal velocity model to the vehicular motion. If the incoming vehicle does not decelerate successfully, it crashes into the vehicle ahead. On the other hand, if the headway between the incoming vehicle and the vehicle behind on the second lane is not long sufficiently, the rear vehicle may come into collision with the incoming vehicle. The safety-collision transition occurs by changing the lane. The dynamical transition depends highly on the vehicular speed, the sensitivity, and the headway. We derive the phase diagram (or region map) for the safety-collision transition.     

Micro-magnetic resonance imaging study of live quail embryos during embryonic development

Eggs containing live Japanese quail embryos were imaged using micro-magnetic resonance imaging (μMRI) at 24-h intervals from Day 0 to 8, the period during which the main body axis is being laid down and organogenesis is taking place. Considerable detail of non-embryonic structures such as the latebra was revealed at early stages but the embryo could only be visualized around Day 3. Three-dimensional (3D) changes in embryo length and volume were quantified and also changes in volume in the extra- and non-embryonic components. The embryo increased in length by 43% and nearly trebled in volume between Day 4 and Day 5. Although the amount of yolk remained fairly constant over the first 5 days, the amount of albumen decreases significantly and was replaced by extra-embryonic fluid (EEF). ¹H longitudinal (T₁) and transverse (T₂) relaxation times of different regions within the eggs were determined over the first 6 days of development. The T₂ measurements mirrored the changes in image intensity observed, which can be related to the aqueous protein concentrations. In addition, a comparison of the development of Day 0 to 3 quail embryos exposed to radiofrequency (rf) pulses, 7 T static magnetic fields and magnetic field gradients for an average of 7 h with the development of control embryos did not reveal any gross changes, thus confirming that μMRI is a suitable tool for following the development of live avian embryos over time from the earliest stages.     

An integrated toolchain for model based functional safety analysis

The significant increase in the complexity and autonomy of the hardware systems renders the verification of the functional safety of each individual component as well as of the entire system a complex task and underlines the need for integrated, model based tools that would assist this process. In this paper the authors present such a tool, coupled with an approach to functional safety analysis, based on the integration of functional tests into the model itself. The analysis of the resulting model is done through a stochastic Bayesian model. This approach strives to both bypass the necessity for costly hardware testing and integrate the functional safety analysis into an intuitive component development process.     

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在HL-2A装置上发展了两类动态斯塔克效应(MSE)偏振仪并应用于磁场倾斜角的测量。其中被称为比值法的MSE系统误差可以被控制在±0.15°以内。在HL-2A装置实验中,利用该方法成功获得7个空间点、径向覆盖范围为24cm的磁场倾斜角剖面分布,其时间分辨可达到40ms。应用平衡重建代码(EFIT)结合MSE测量数据的限定,可以得到安全因子(q)的径向分布,其中 q=1面的位置与软 X 射线测量得到锯齿振荡反转面的位置一致。调制法MSE在标定实验中误差也可控制在±0.15°以内。实验结果表明偏振片透振方向与双光学弹性调制器(dual PEM)快轴夹角平分线的偏差对系统的线性和误差均有较大的影响。目前,该系统已经建成一个空间通道,测得磁场倾斜角的时间分辨可以达到20ms。     

Safety of ultrasound-guided high-intensity focused ultrasound ablation for diffuse adenomyosis: A retrospective cohort study

ObjectivesTo evaluate the safety of ultrasound-guided high-intensity focused ultrasound (HIFU) ablation for patients with diffuse adenomyosis.MethodsThis was a retrospective cohort study. The data was collected from 417 symptomatic adenomyosis patients who underwent ultrasound-guided HIFU between January 2012 and December 2015 at 1st Affiliated Hospital of Chongqing Medical University, Chongqing, China. Among them were 260 patients with diffuse adenomyosis (Group D) and 157 patients with focal adenomyosis (Group F). All patients underwent contrast-enhanced magnetic resonance imaging (MRI) one week before and the day after HIFU treatment. Successful treatment with HIFU was measured by the non-perfused volume ratio (NPVR). Intraprocedural and postprocedural adverse effects and complications were recorded to assess the safety of the procedure. Patients were followed-up for three months post-treatment. Complications were given a grade A through F according to the SIR Standards.ResultsAll patients successfully completed the procedure, non-perfused regions appeared in 415 (99.5%) patients. The non-perfused volume ratio (NPVR) of Group D was significantly lower than that of Group F (P < 0.05). During the procedure, the odds ratio of skin-burning pain was 1.7 (OR = 1.617, 95% CI: 1.103–2.532), when comparing Group D with Group F, while the odds ratio of inguinal pain was equal to 2.0 (OR = 2.038, 95% CI: 1.161–3.580), when Group F was compared to Group D. 97 patients (23.3%) received nominal therapy due to complications ([Society of interventional radiology, SIR]-B grade), among them, there were 62 cases (23.8%) in Group D and 35 cases (22.3%) in Group F. No significant difference was found between the two groups (P > 0.05) and neither of the reported complications of SIR-C-SIR-F occurred within the two groups.ConclusionsBased on our results, ultrasound-guided HIFU is safe for the treatment of diffuse adenomyosis, and controlling the ablation zone is crucial to ensure patients’ safety.     

Multiple-vehicle collision induced by a sudden stop in traffic flow

We study the dynamic process of the multiple-vehicle collision when a vehicle stops suddenly in a traffic flow. We apply the optimal-velocity model to the vehicular motion. If a vehicle does not decelerate successfully, it crashes into the vehicle ahead with a residual speed. The collision criterion is presented by _vi(t)/Δ_xi(t)→∞$v_i(t)/\mathrm{\Delta }{x}_i(t)\to \infty$ if Δ_xi(t)→0$\mathrm{\Delta }{x}_i(t)\to 0$ where _vi(t)$v_i(t)$ and Δ_xi(t)$\mathrm{\Delta }{x}_i(t)$ are the speed and headway of vehicle i at time t. The number of crumpled vehicles depends on the initial velocity, the sensitivity, and the initial headway. We derive the region map (or phase diagram) for the multiple-vehicle collision.