BEPCII次谐波聚束系统物理公差要求的研究

为了进一步提高束流品质并逐步采用双束加速技术, BEPCII直线加速器准备采用带有两个次谐波聚束器的双次谐波聚束系统。目前, 该次谐波聚束系统的物理设计和优化已经基本完成。由于新设计的双次谐波聚束系统很不同于BEPCII现有的聚束系统, 因此, 就要求对聚束系统中存在的各种抖动(jitter)效应重新进行研究。 使用多粒子模拟计算程序PARMELA对电子枪的高压抖动和定时抖动、次谐波聚束器的相位抖动以及功率抖动、聚束器中加速电场相位以及A0加速管(俘获加速节)中加速电场相位的抖动等效应进行了研究, 并最终确定了聚束系统中各部件的物理公差要求。     

大气压力对激光辐照双层板接触传热的影响

考虑激光辐照下结构变形对双层板接触传热影响可以更真实地反映两板间的传热情况,通过实验和数值模拟分析了大气压力对接触传热的影响。结果表明：大气压力对接触热阻影响非常明显,当大气压力超过一定值后,双层板界面始终接触,后板中心的温升阶段成类抛物形状;当大气压力在某一范围内,大气压力与温度矩产生的靶板挠度相当,接触面时分时合,后板的温升阶段成振荡式类线性增加;当大气压力小于某一特定值时,后板温度有一突跃过程,通过适当的设计有可能观测到该现象。     

Preparation and Characterization of an Ancient Aminopeptidase Obtained from Ancestral Sequence Reconstruction for L-Carnosine Synthesis

As a biologically active peptide, L-carnosine has been widely used in the pharmaceutical, cosmetic and health care industries due to its various physiological properties. However, relatively little research is available regarding L-carnosine’s enzymatic synthesis function. In this study, a potential enzyme sequence with the function of carnosine synthesizing was screened out using the ancestral sequence reconstruction (ASR) technique. Identified with L-carnosine synthesis activity, this enzyme was further confirmed using autoproteolytic phenomenon via Western blot and N-terminal sequencing. After purification, the enzymatic properties of LUCA–DmpA were characterized. The melting temperature (T_m) and denaturation enthalpy (ΔH) of LUCA–DmpA were 60.27 ± 1.24 °C and 1306.00 ± 26.73 kJ·mol⁻¹, respectively. Circular dichroism (CD) spectroscopy results showed that this ancestral enzyme was composed of α-helix (35.23 ± 0.06%), β-sheet (11.06 ± 0.06%), β-turn (23.67 ± 0.06%) and random coil (32.03 ± 0.06%). The enzyme was characterized with the optimal temperature and pH of 45 °C and 9.0, respectively. Notably, LUCA–DmpA was also characterized with remarkable pH tolerance based on the observation of more than 85% remaining enzymatic activity after incubation at different pH buffers (pH = 6–11) for 12 h. Additionally, rather than being improved or inhibited by metal ions, its enzymatic activity was found to be promoted by introducing organic solvent with a larger log P value. Based on these homology modeling results, the screened LUCA–DmpA is suggested to have further optimization potential, and thereafter to be offered as a promising candidate for real industrial applications.     

Optimizing inputs for diagnosis of diabetes. I. Fitting a minimal model to data

A glucose tolerance test was performed on dogs by injecting glucose intravenously and measuring the plasma glucose and insulin concentrations versus time. Various analytical and computational techniques were utilized to fit the data to a minimal model and to estimate the parameters of the blood glucose regulation process. A relatively good fit was obtained in spite of the rather simple model.Animal experiments were funded by the National Institute of Health Grant No. AM-17236 awarded to Dr. R. N. Bergman at U.S.C.     

高铁锻钢制动盘热疲劳裂纹扩展仿真及寿命评价

巨大的制动热能导致高铁制动盘面出现热斑或热点,形成沿径向扩展的热疲劳裂纹,严重危及行车安全.通过仿真获得热疲劳裂纹扩展规律,据此制定出合适、经济的检测周期,具有重要意义.基于断裂力学理论,采用扩展有限单元法和自主研发的裂尖网格加密技术,得到热点形成规律,植入半椭圆形裂纹进行热疲劳断裂仿真,得到制动速度为400 km/h...     

用于质子交换膜燃料电池抗CO的Pt-CeO2/C催化剂的制备和表征

采用一步沉淀法,制备了纳米级Pt-CeO2/C电催化剂.透射电镜和X射线衍射表征结果表明,制备的催化剂Pt颗粒均匀分散于碳载体表面,其粒径主要分布于1.5～2.5 nm.将Pt-CeO2/C催化剂制备成质子交换膜燃料电池膜电极,经循环伏安和单电池极化曲线测试发现,Pt-CeO2/C催化剂性能与Pt/C催化剂的相当.一氧...     

Tolerance graphs,and orders

We show that, if a tolerance graph is the complement of a comparability graph, it is a trapezoid graph, i.e., the complement of an order of interval dimension at most 2. As consequences we are able to give obstructions for the class of bounded tolerance graphs and to give an example of a graph that is alternatingly orientable but not a tolerance graph. We also characterize the tolerance graphs among complements of trees. © 1998 John Wiley & Sons, Inc. J. Graph Theory 28: 129–140, 1998     

恒定pH系统中不同大麦品种的耐铝性

本文提出以相对生长率衡量耐铝性，基本上排除了系统所造成的误差.以相对生长率P衡量根的耐铝性，在恒定的pH系统(pH4. 75士0. 1)中3ppm铝胁迫下，经大田鉴定的一级耐性品种B和H表现了不同的相对生长率，品种B的相对生长率达28%，而品种H只有1400,中等敏感品种Z为15%，而敏感品种S可达17%.结果说明:品种H的耐铝性可能是通过升高根际pH，降低铝的解离程度而实现的.而品种B的耐铝性机制与品种H不同，其耐铝性与根际pH值调节基本无关.     

多层介质膜光谱调制反射镜的反应离子束刻蚀误差容限

 在千焦拍瓦高功率放大系统设计中,激光脉冲的时空和光谱整形技术一直受到人们的广泛关注。利用反应离子束刻蚀等微纳超精细加工而成的多层电介质结构反射镜可在高功率条件下实现啁啾脉冲的光谱整形。在光谱整形介质结构反射镜的设计与制造中,需要根据要求的反射率来合理提出反应离子束刻蚀误差容限指标。推导出反应离子束刻蚀误差容限的解析表达式。针对神光Ⅱ千焦拍瓦高功率放大系统设计中提出的多层介质光谱调制反射镜,分析了调制结构反射镜各层加工的容许误差,确定了反应离子束刻蚀误差容限指标。研究表明：刻蚀高折射率介质的加工误差容限为35 nm;刻蚀低折射率介质的加工误差容限为62 nm。此外,还从使用需要和加工难易的角度,对刻蚀方案进行了讨论。就加工难易程度而言,优选反应离子束刻蚀方案,且采用刻蚀并残留低折射率介质的方案更容易实现。