三波长融合指纹图谱结合6组分定量和主成分分析评价银翘解毒片的质量

建立了三波长融合高效液相色谱指纹图谱,并结合6组分定量和主成分分析(PCA)评价25批银翘解毒片的质量一致性。采用反相高效液相色谱法(RP-HPLC)分别于230、279、327 nm下检测。运用多波长融合指纹图谱技术建立银翘解毒片三波长融合指纹图谱,采用系统指纹定量法对其进行定性和整体定量评价。结果鉴别出25批银翘解毒片样品完全合格且区分良好。同时测定6组分含量,与指纹图谱结合,从整体和局部角度评价银翘解毒片质量。此外,运用PCA法对融合指纹图谱进行分析,通过主成分得分图可以明显区分来自两个厂家的25批银翘解毒片样品。方法综合性较强且有效,为科学评价与有效控制银翘解毒片的质量提供了可靠的参考。     

Allowance for the imperfection of optical elements and inaccuracy in the initial adjustment of the rotating phase plate in a stokes polarimeter

For a Stokes polarimeter with a rotating phase plate, formulas were obtained for calculating the polarization characteristics and their systematic errors caused by the departure of the anisotropy parameters of the optical elements used from ideal ones and also by the deflection of the initial position of the phase plate "fast" axis from the analyzer transmission axis. The manifestation of the mentioned factors in the systematic errors of determining the polarization characteristics of radiation of different forms of polarization is considered. The results of model calculations have been confirmed by experimental data. Translated from Zhurnal Prikladnoi Spektroskopii, Vol. 67, No. 3, pp. 382–386, May–June, 2000. This work was carried out with partial support from the Belarusian Foundation for Fundamental Research (project F97-184).     

Systematic and statistical errors in quantitative evaluation using TLC and HPTLC. 2. Internal and external standard methods

The error propagation is given for routine analysis by in situ evaluation in TLC using the methods with internal or external standard. The internal standard method will need four different measurements of peak height or area, while the external standard method uses only two measurements. Therefore in the latter case the error of the spotting volume will cause errors in the determined concentration. By error propagation it can be shown, that the internal standard method gives better results, if the error in measuring peak height or area is less than the error of the spotting volume.     

山东电视观众满意度调查抽样方案设计

本文给出山东电视观众满意度调查的抽样方案设计 ,构造了两类目标量的估计量 ,并对估计量的精度进行了分析。     

在几种常见的抽样方案下的事后分层

本文给出系统抽样，放回不等概率抽样及二阶不等概率抽样情况下总体均值的事后分层估计，估计量的方差和它的无偏估计。     

Focused grid‐based resampling for protein docking and mapping

The fast Fourier transform (FFT) sampling algorithm has been used with success in application to protein‐protein docking and for protein mapping, the latter docking a variety of small organic molecules for the identification of binding hot spots on the target protein. Here we explore the local rather than global usage of the FFT sampling approach in docking applications. If the global FFT based search yields a near‐native cluster of docked structures for a protein complex, then focused resampling of the cluster generally leads to a substantial increase in the number of conformations close to the native structure. In protein mapping, focused resampling of the selected hot spot regions generally reveals further hot spots that, while not as strong as the primary hot spots, also contribute to ligand binding. The detection of additional ligand binding regions is shown by the improved overlap between hot spots and bound ligands. © 2016 Wiley Periodicals, Inc.     

基于网络的系统性风险测度方法及其在中国银行业的应用

全球金融危机、英国公投脱欧等事件无不冲击着中国银行业,系统性风险的准确预测再一次成为了关注的焦点.随着互联互通程度的增强,网络效应成为了系统性风险研究所必要考虑的因素.完全从网络内部影响的视角,通过计算资产间相关性系数来构建网络,再考虑网络效应推导资产组合理论从而得出新的风险度量公式.之后,选取了10家银行为研究对象,分析了其在2008年1月至2016年6月的风险变化情况.最后,通过对比得出新构建公式预测风险具有准确度高、参考价值大和及时性强等优点.     

基于声矢量水听器阵列误差的自校正算法

对声矢量水听器阵列的各类误差进行了分类,推导了各类误差对阵列信号模型的影响因子,通过Monte Carlo实验分析对比了各类误差对阵列DOA估计性能的影响,然后将方向性误差和位置误差归结为幅度误差和相位误差,在传统声压阵列误差校正模型和算法的基础上,得到矢量阵列误差自校正的优化模型及自校正算法,最后,通过仿真实验和外场实验的数据处理表明,自校正算法具有良好的参数估计性能,具有一定的工程实用性.     

激光陀螺捷联惯导系统参数稳定性与外场自标定

惯导系统参数稳定性是决定系统精度的重要因素。基于激光陀螺捷联惯导系统参数稳定性统计分析,建立了适合激光陀螺捷联惯导系统外场自标定的加速度计组件误差参数模型。以惯性组合转动后重新调平的水平姿态修正量以及静态下重力测量误差为观测量,不依赖外界方向姿态转角等基准信息,实现了加速度计组件主要误差参数在外场条件下的自标定,并给出了标定参数的修正方法。实验表明,常温下加速度计组件的标定参数发生明显变化,采用外场标定方法可对其进行修正,相应的水平姿态最大误差由65″减小到10″。该方法标定精度好,标定时间短,操作简便,且对基座不稳造成的瞬时姿态小扰动影响有抑制能力。     

Effects of a Time-Varying Color-Luminosity Parameter β on the Cosmological Constraints of Modified Gravity Models

It has been found that, for the Supernova Legacy Survey three-year (SNLS3) data, there is strong evidence for the redshift-evolution of color-luminosity parameter β. In previous studies, only dark energy (DE) models are used to explore the effects of a time-varying β on parameter estimation. In this paper, we extend the discussions to the case of modified gravity (MG), by considering Dvali-Gabadadze-Porrati (DGP) model, power-law type f(T) model and exponential type f(T) model. In addition to the SNLS3 data, we also use the latest Planck distance priors data, the galaxy clustering (GC) data extracted from Sloan Digital Sky Survey (SDSS) data release 7 (DR7) and Baryon Oscillation Spectroscopic Survey (BOSS), as well as the direct measurement of Hubble constant H₀ from the Hubble Space Telescope (HST) observation. We find that, for both cases of using the supernova (SN) data alone and using the combination of all data, adding a parameter of β can reduce χ² by ～ 36 for all the MG models, showing that a constant β is ruled out at 6σ confidence level (CL). Moreover, we find that a time-varying β always yields a larger fractional matter density Ω_m0 and a smaller reduced Hubble constant h; in addition, it significantly changes the shapes of 1σ and 2σ confidence regions of various MG models, and thus corrects systematic bias for the parameter estimation. These conclusions are consistent with the results of DE models, showing that β's evolution is completely independent of the cosmological models in the background. Therefore, our work highlights the importance of considering the evolution of β in the cosmology-fits.