岩质滑坡的时间预报与水力启动模型

摘  要  岩质滑坡发生时间的适时超前预报是一个世界性难题,之所以长期不得其解,主要是缺乏对滑坡成生机理的明晰认识和未建立正确的量化模型。本文根据我国长江三峡工程库岸和西南山区积累的大量滑坡实例调查资料并参考国外的一些研究成果,排除了地形控制论与地层控制论观点,阐明了滑坡形成的必要条件是斜坡具有易滑结构;滑坡发生的充分条件是有一定强度的诱发因素作用。故而诱发因素的动态变化对滑坡发生的时间具决定意义。
鉴于地下水诱发的岩质滑坡分布最广,为建立正确的水力启动模型,本文归纳了近代典型岩质滑坡的主要特征：（1）滑面是导水性差异最大的贯通面;（2）滑体长度大而厚度小,长厚比多在20左右;（3）滑坡前缘段先启动;（4）临滑前在前缘段有渗水、冒水或喷水现象;（5）出水宽度之和远小于前缘段总宽度。根据这些特征和水力学、水文地质学的成熟理论指出jennings（1970）等人提出的岩质斜坡稳定性模型存在下列问题：（1）未表明贯通面上岩体重力分布状况;（2）空隙水压力的分布特征与前述滑坡现象和水力学原理相悖;（3）未考虑通水率问题。然后,本文按顺向坡中的易滑超倾坡和椅状坡两个类型建立了斜坡稳定性模型和滑坡水力启动临界值（基本）计算公式。提出潜滑面的综合内摩擦角和通水率的确定方法：（1）滑坡反算;（2）对无水压滑坡滑面倾角和渗水边坡通水率进行观测统计;（3）剪切试验和简易水文地质试验;（4）物探方法。
本文还讨论了新模型的实用意义和应用范围,并对解决这类复杂地质灾害问题的研究途径发表了作者的认识,强调了积累经验的重要性。     

Exploring the Interaction of G-quadruplex Binders with a (3 + 1) Hybrid G-quadruplex Forming Sequence within the PARP1 Gene Promoter Region

The enzyme PARP1 is an attractive target for cancer therapy, as it is involved in DNA repair processes. Several PARP1 inhibitors have been approved for clinical treatments. However, the rapid outbreak of resistance is seriously threatening the efficacy of these compounds, and alternative strategies are required to selectively regulate PARP1 activity. A noncanonical G-quadruplex-forming sequence within the PARP1 promoter was recently identified. In this study, we explore the interaction of known G-quadruplex binders with the G-quadruplex structure found in the PARP gene promoter region. The results obtained by NMR, CD, and fluorescence titration, also confirmed by molecular modeling studies, demonstrate a variety of different binding modes with small stabilization of the G-quadruplex sequence located at the PARP1 promoter. Surprisingly, only pyridostatin produces a strong stabilization of the G-quadruplex-forming sequence. This evidence makes the identification of a proper (3+1) stabilizing ligand a challenging goal for further investigation.     

Improvements to a smooth particle hydrodynamics simulator for investigating submarine landslide generated waves

Submarine landslides can exhibit complex rheologies, including a finite yield stress and shear thinning, yet are often simulated numerically using a Newtonian fluid rheology and simplistic boundary conditions. Here we present improvements made to a Smoothed Particle Hydrodynamics simulator to allow the accurate simulation of submarine landslide generated waves. The improvements include the addition of Bingham and Herschel-Bulkley rheologies, which better simulate the behavior of submarine mudflows. The interaction between the base of the slide and the slope is represented more accurately through the use of a viscous stress boundary condition. This condition treats the interface between the seafloor and the slide as a fluid boundary layer with a user-defined viscosity and length scale. Modifications to the pressure and density calculations are described that improve their stability for landslide generated wave scenarios. An option for pressure decomposition is introduced to prevent particle locking under high pressure. This facilitates the application of this simulator to landslide scenarios beneath significant water depths. Additional modifications to the reaveraging and renormalization routines improve the stability of the free surface and fluid density. We present the mathematical formulations of these improvements alongside commentary on their performance and applicability to landslide generated wave modeling. The modifications are verified against analytical fluid flow solutions and a wave generation experiment.     

Stress‐Induced Stabilization of Crystals in Shape Memory Natural Rubber

In contrast to all known shape memory polymers, the melting temperature of crystals in shape memory natural rubber (SMNR) can be greatly manipulated by the application of external mechanical stress. As shown previously, stress perpendicular to the prior programming direction decreases the melting temperature by up to 40 K. In this study, we investigated the influence of mechanical stress parallel to prior stretching direction during programming on the stability of the elongation‐stabilizing crystals. It was found that parallel stress stabilizes the crystals, which is indicated by linear increase of the trigger temperature by up to 17 K. The crystal melting temperature can be increased up to 126.5 °C under constrained conditions as shown by X‐ray diffraction measurements.     

瓦屋山水电站厂房区红层岩体古滑坡稳定性研究

红层岩体以其岩体结构的软硬相间及软弱夹层发育而在边坡稳定方面表现为"易滑地层"。瓦屋山水电站厂房区边坡为顺向坡,砂岩类岩石与黏土岩类岩石呈缓倾、互层状(倾角10°~20°)产出。构造与表生改造作用下,在这两类软硬相间的岩石界面上常形成分布较为连续的软弱夹层,这类岩体较易沿软弱夹层产生顺层滑动。地质历史时期,瓦屋山厂房区就是在这样的地质背景下,形成了多个古滑坡体,如颜湾和庙子岩古滑坡,它们在自然状态下已基本稳定。随后因风化剥蚀等作用,古滑坡体形态被改变或被来自后缘斜坡的坡残积层所掩埋,使其在勘察期间难以被发现。庙子岩滑坡即是这样一个被掩埋的古滑坡体坡,施工开挖过程中,由于切脚及降雨作用,使其重新滑动复活。本文以反复剪试验得到的滑动面抗剪参数,采用边坡稳定极限分析能量法(Energy Method Upper Baond Limit Analysis),简称EMU法,对庙子岩古滑坡在各种工况下的稳定作了计算,并据其结果采取了相应的抗滑处理。本文可作为红层岩体地区该类型滑坡勘察和工程处理设计的参考。     

Analytical solution for laterally loaded long piles based on Fourier–Laplace integral

Piles are frequently used to support lateral loads. Elastic solutions based on the Winkler foundation model are widely used to design laterally loaded piles at working load. This paper reports a simplified analytical solution for laterally loaded long piles in a soil with stiffness linearly increasing with depth. Based on a Fourier–Laplace integral, a power series solution for small depth and a Wentzel–Kramers–Brillouin (WKB) asymptotic solution for large depth are derived. By using this analytical solution, the deflection and bending moment profiles of a laterally loaded pile can be obtained through simple calculation. The proposed power series solution is exact for infinitely long piles. Numerical examples show that this solution agrees well with other existing methods on predicting the deflection and bending moment of laterally loaded piles. The WKB asymptotic solution developed in this study has never been introduced before. The simplified analytical solution obtained in this study provides a better approach for engineers to analyze the responses and design of laterally loaded long piles.     

基于决策树算法的滑坡危险性区划评价

以浙江庆元县境内滑坡发生集中区为试验区,获取与滑坡危险性有关的因素集,包括数字高程、坡度、对应分析因子、地质图等,采用决策树算法对因素集数据进行数据挖掘,开展滑坡危险性区划,取得了与实际较为一致的结果.因此,利用决策树归纳技术可以快速准确地实现滑坡灾害区域评价与预测,是一种较好的滑坡灾害危险性评价方法.     

神经网络与符号推理集成系统在桩基检测中的初步应用

本文提出一种神经网络与符号推理集成系统ＩＮＮＳＩ（ＩｎｔｅｇｒａｔｉｏｎｏｆＮｅｕｒａｌＮｅｔｗｏｒｋａｎｄＳｙｍｂｏｌｉｃＩｎｆｅｒｅｎｃｅ）。该系统的特点是领域规则和学习样本能够共同对系统做出贡献。通过桩基完整性检测仿真试验，验证了应用该方法检测桩基的完整性是有效的，并且优于单独使用符号推理方法或神经网络方法。     

排水粉喷桩(2D工法)中粉喷桩成桩质量试验研究

通过现场单桩及群桩试验研究,对比了粉喷桩周围是否打设塑料排水板时粉喷桩成桩质量的差异。试验结果表明,在粉喷桩桩周预先打设塑料排水板,利用排水板的排水导气作用,可以有效的提高粉喷桩沿桩身的喷粉均匀性,提高粉喷桩的桩身搅拌均匀性,从而提高桩身质量,特别是明显提高深部桩身质量,因此加大了粉喷桩加固软土地基的处理深度。     

被动桩中土拱效应特征与影响参数研究

采用平面有限元方法,对被动桩在粘性、无粘性土体条件下的土拱形成机理进行了分析。从土拱效应的4个主要方面:土拱形状、桩周土体塑性(拉裂)区的分布、竖向位移等值线及桩后土体残余荷载分担比,探讨了改变桩、土参数,如粘聚力、内摩擦角、弹性模量、泊松比、剪胀角、桩土接触面特性时,土拱效应的变化规律。研究表明,土性不同时,土拱形成过程中土体的受力和破坏形式不同;泊松比、剪胀角、桩土接触特征对土拱效应的影响最明显;强度高、剪胀角大、桩土接触面粗糙或泊松比小的土体,易形成土拱。根据研究结果,指出Tom io Ito排桩塑性绕流土压力理论计算公式尚存不足。