非定常机匣处理扩稳实验研究

针对一种非定常处理机匣,在轴流风扇实验台上开展偏流吹气扩稳实验研究.主要包括t改善风扇稳定裕度的稳态特性;影响失速先兆波产生及发展的动态分析.结果表明:非定常机匣处理能够在不同工作转速下对风扇稳定裕度有显著效果,效率没有明显改变.偏流吹气可以进一步改善风扇稳定裕度,但同时也会带来一定的效率损失.动态分析证实处理机匣没有阻止失速先兆波的出现.而是有效地抑制了其非线性发展.     

Decontamination Efficiency of Thermal,Photothermal, Microwave,and Steam Treatments for Biocontaminated Household Textiles

With the outbreak of the COVID-19 pandemic, textile laundering hygiene has proved to be a fundamental measure in preventing the spread of infections. The first part of our study evaluated the decontamination efficiency of various treatments (thermal, photothermal, and microwave) for bio contaminated textiles. The effects on textile decontamination of adding saturated steam into the drum of a household textile laundering machine were investigated and evaluated in the second part of our study. The results show that the thermal treatment, conducted in a convection heating chamber, provided a slight reduction in efficiency and did not ensure the complete inactivation of Staphylococcus aureus on cotton swatches. The photothermal treatment showed higher reduction efficiency on contaminated textile samples, while the microwave treatment (at 460 W for a period of 60 s) of bio contaminated cotton swatches containing higher moisture content provided satisfactory bacterial reduction efficiency (more than 7 log steps). Additionally, the treatment of textiles in the household washing machine with the injection of saturated steam into the washing drum and a mild agitation rhythm provided at least a 7 log step reduction in S. aureus. The photothermal treatment of bio contaminated cotton textiles showed promising reduction efficiency, while the microwave treatment and the treatment with saturated steam proved to be the most effective.     

Identification of New Non-BBB Permeable Tryptophan Hydroxylase Inhibitors for Treating Obesity and Fatty Liver Disease

Serotonin (5-hydroxytryptophan) is a hormone that regulates emotions in the central nervous system. However, serotonin in the peripheral system is associated with obesity and fatty liver disease. Because serotonin cannot cross the blood-brain barrier (BBB), we focused on identifying new tryptophan hydroxylase type I (TPH1) inhibitors that act only in peripheral tissues for treating obesity and fatty liver disease without affecting the central nervous system. Structural optimization inspired by para-chlorophenylalanine (pCPA) resulted in the identification of a series of oxyphenylalanine and heterocyclic phenylalanine derivatives as TPH1 inhibitors. Among these compounds, compound 18i with an IC₅₀ value of 37 nM was the most active in vitro. Additionally, compound 18i showed good liver microsomal stability and did not significantly inhibit CYP and Herg. Furthermore, this TPH1 inhibitor was able to actively interact with the peripheral system without penetrating the BBB. Compound 18i and its prodrug reduced body weight gain in mammals and decreased in vivo fat accumulation.     

应变对纳米铜晶界迁移的影响

用分子动力学方法模拟了金属铜纳米双晶中晶界在应变作用下的迁移过程,晶界类型为〈11l〉倾侧∑19晶界。原子问相互作用力采用Finnis-Sinclair型EAM势计算。结果表明：平行于晶界方向的压应变可以促进晶界在相邻品界交互作用下发生迁移;垂直于晶界方向的压应变则不能对晶界迁移产生明显的效果。晶界迁移大致可分为两个阶段,前阶段晶界迁移缓慢,随晶界间距减小,晶界间交互作用加强,使晶界迁移显著加速。     

6H-SiC衬底片的表面处理

相比于蓝宝石,6H-SiC是制作GaN高功率器件更有前途的衬底.本文研究了表面处理如研磨、化学机械抛光对6H-SiC衬底表面特性的影响.用显微镜、原子力显微镜、拉曼光谱、卢瑟福背散射谱表征了衬底表面.结果表明经过两步化学机械抛光后提高了表面质量.经第二步化学机械抛光后的衬底具有优异的表面形貌、高透射率和极小的损伤层,其表面粗糙度RMS是0.12nm.在该衬底上用MOCVD方法长出了高质量的GaN外延膜.     

DUAL RECIPROCITY HYBRID BOUNDARY NODE METHOD FOR THREE-DIMENSIONAL ELASTICITY WITH BODY FORCE

Combining Dual Reciprocity Method （DRM） with Hybrid Boundary Node Method （HBNM）, the Dual Reciprocity Hybrid Boundary Node Method （DRHBNM） is developed for three-dimensional linear elasticity problems with body force. This method can be used to solve the elasticity problems with body force without domain integral, which is inevitable by HBNM. To demonstrate the versatility and the fast convergence of this method, some numerical examples of 3-D elasticity problems with body forces are examined. The computational results show that the present method is effective and can be widely applied in solving practical engineering problems.     

Correlation between Irradiation Treatment and Metabolite Changes in Bactrocera dorsalis (Diptera: Tephritidae) Larvae Using Solid-Phase Microextraction (SPME) Coupled with Gas Chromatography-Mass Spectrometry (GC-MS)

The metabolites produced by the larvae of Bactrocera dorsalis (Diptera: Tephritidae) exposed to different doses of irradiation were analyzed using solid phase microextraction (SPME) and gas chromatography-mass spectrometry (GC-MS), and a metabonomic analysis method of irradiated insects based on GC-MS was established. The analysis revealed 67 peaks, of which 23 peaks were identified. The metabolites produced by larvae treated with different irradiation doses were compared by multivariate statistical analysis, and eight differential metabolites were selected. Irradiation seriously influenced the fatty acid metabolic pathway in larvae. Using the R platform combined with the method of multivariate statistical analysis, changes to metabolite production under four irradiation doses given to B. dorsalis larvae were described. Differential metabolites of B. dorsalis larvae carried chemical signatures that indicated irradiation dose, and this method is expected to provide a reference for the detection of irradiated insects.     

动边界量子含时谐振子系统的Lewis-Riesenfeld相位与Berry相位

根据Lewis-Riesenfeld的量子不变量理论,计算了一维动壁无限深势阱内频率随时间变化的谐振子的Lewis-Riesenfeld相位,发现刘登云文中“非绝热Berry相位”与Lewis-Riesenfeld相位中的几何部分完全一致.也许更为重要的是,证明了至少对于做正弦振动的边界,在绝热近似下,该系统不存在非零的Berry相位. 关键词： Berry相位 Lewis-Riesenfeld相位 量子不变量 动边界     

Preparation of CdO nanoparticles by mechanochemical reaction

CdO nanoparticles of 43 nm in crystal size were successfully synthesized by the mechanochemical reaction (CdCl₂ + Na₂CO₃) with NaCl as a diluent and subsequent thermal treatment at 700°C for 2 h. The samples were characterized by differential thermal analysis (DTA), thermogravimetric analysis (TGA), X-ray diffraction (XRD) and transmission electron microscopy (TEM). Effect of calcination temperature on the crystal size of CdO nanoparticles was primarily investigated. The apparent activation energy of CdO nanoparticle formation during thermal treatment was calculated to be 12.2 kJ/mol.     

光滑粒子流体动力学方法固壁处理的一种新型排斥力模型

与传统网格法相比, 光滑粒子流体动力学方法不能直接施加壁面边界条件, 这就限制了该方法在工程中的应用.为此, 本文基于Galerkin加权余量法并结合传统排斥力方法, 推导出一种新的排斥力公式来施加壁面边界条件.该方法不含未知参数, 能在不减小边界粒子尺寸的情形下有效地防止流体粒子穿透壁面, 同时可避免邻近边界的流体粒子的速度及压力振荡. 分别通过静止液柱算例、液柱坍塌算例、容器中液体静止算例及溃坝算 例来验证本文方法的有效性, 并与传统边界处理方法进行对比, 结果表明: 本文方法克服了传统方法存在的缺陷, 是一种有效的固壁边界处理方法. 关键词： 光滑粒子流体动力学法 固壁边界 排斥力 加权余量法