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951.
Proteins are the most essential macromolecules needed for the normal flow of life. Essential proteins play a key role to control other proteins in an interaction network for the growth and understanding of the molecular mechanism of cellular life. Though there are many computational algorithms for essential drug discovery depending on nature of essential proteins, but still lots of improvements and optimizations are required. In this work, modified-Monkey algorithm (MMA) is proposed for the identification of essential proteins in protein-protein interaction network (PPIN). Nature of a monkey can be distinctly described in three processes like climb, watch-jump, and somersault in different problem spaces. These processes of monkey traversal are plotted in PPIN with objective to find out essential proteins. Performance of MMA is assessed with other existing essential protein prediction methodologies, including Eigenvector Centrality (EC), Betweenness Centrality (BC), Network Centrality (NC) and others also. The proposed methodology has achieved higher success rates in comparison to the existing state-of-art model. 相似文献
952.
Mengyi Zhang Jens Becking Marian Cristian Stan Arthur Lenoch Peter Bieker Martin Kolek Martin Winter 《Angewandte Chemie (International ed. in English)》2020,59(39):17145-17153
Li metal batteries (LMBs) containing cross‐linked polymer electrolytes (PEs) are auspicious candidates for next‐generation batteries. However, the wetting behavior of PEs on uneven Li metal surfaces has been neglected in most studies. Herein, it is shown that microscale defect sites with curved edges play an important role in a wettability‐dependent electrodeposition. The wettability and the viscoelastic properties of PEs are correlated, and the impact of wettability on the nucleation and diffusion near the Li|PE interface is distinguished. It is found that the curvature of the edges is a key factor for the investigation of wetting phenomena. The appearance of microscale defects and phase separation are identified as main causes for erratic nucleation. It is emphasized that the implementation of stable and consistent long‐term cycling performance of LMBs using PEs requires a deeper understanding of the “soft‐solid”–solid contact between PEs and inherently rough Li metal surfaces. 相似文献
953.
954.
《Physics letters. A》2020,384(27):126703
Understanding the emergence and maintenance of cooperation in social dilemma has received a lot of attention. In previous research, many scholars found that the reputation mechanism can promote cooperation, and the variation of reputation is consistent. However, in reality, according to both one's current action and past experiences, every individual's impression from others is modified to varying extent everyday. In other words, the length of duration of the same performance influences the diverse scale of their own reputation fluctuation. Therefore, a reputation-based strategy persistence mechanism, in which the increment of current reputation is determined by the persistence of last strategy, is proposed. Moreover, we introduce a parameter α to illustrate the impact of strategy persistence on reputation variation. The results of simulation show that the new mechanism paves the way for cooperation in evolutionary game, and the smaller α is, the better the mechanism performs. 相似文献
955.
《Physics letters. A》2020,384(35):126895
Networks offer a powerful language with which to describe and study pairwise interaction. However, in many contexts, these rich collective phenomena require a higher-order approach to encode dynamical processes — for example in idea integration and information transmission (co-publication is a particularly familiar example). Here we introduce a novel framework for social communication by reshaping the networked system to be a simplicial complex, where the communication involves the interaction not only of individual nodes but also among cliques to which they belong. Simplicial complexes extend the network-based pairwise relationship to multiagent interaction. Assuming that the same individual in different cliques may play different roles, a threshold is designed and combined with the node state to determine the clique state. We employ the discrete microscopic Markov chain approach to model the simplex-based social communication and then obtain the underlying critical condition for information outbreaks. Moreover, we perform extensive numerical analysis of the proposed simplicial complex-based communication model and compare its performance with Monte Carlo simulation. 相似文献
956.
957.
《Expositiones Mathematicae》2020,38(3):337-364
In this paper, we present two applications of the theory of singular connections developed by Harvey and Lawson (1993). The first one is a version of the Lelong–Poincaré formula with estimates for sections of vector bundles over an almost complex manifold. The second one is a convergence theorem for divisors associated to a general family of symplectic submanifolds constructed by Donaldson (1996) (the case of hypersurfaces) and by Auroux in (1997) (for arbitrary dimensional submanifolds). 相似文献
958.
Xintao Li;Dan Wang ;Xu Wang 《Discrete and continuous dynamical systems》2025,30(5):1779-1808
This paper focuses on the dynamics of nonlocal stochastic complex Ginzburg-Landau lattice systems with delays, driven by nonlinear noise in weighted space. Firstly, we examine the well-posedness of solutions for these stochastic systems and subsequently establish the existence of invariant measures. 相似文献
959.
Based on the basic conclusions of the Riemann–Hilbert method for solving the initial value problem of the complex short-pulse equations, the general form of the two-soliton solutions of the complex short pulse equation is given in this paper. Under the two different assumptions of the scattering coefficient, the expression of the two-soliton solutions of the equation is given specifically. 相似文献
960.