CELL AND MOLECULAR BIOMECHANICS: PERSPECTIVES AND CHALLENGES

As an intriguing interdisciplinary research field,cell and molecular biomechanics is at the cutting edge of mechanics in general and biomechanics in particular.It has the potential to provide a quantitative understanding of how forces and deformation at tissue,cellular and molecular levels affect human health and disease.In this article,we review the recent advances in cell and molecular biomechanics,examine the available computational and experimental tools,and discuss important issues including protein deformation in mechanotransduction,cell deformation and constitutive behavior,cell adhesion and migration,and the associated models and theories.The opportunities and challenges in cell and molecular biomechanics are also discussed.We hope to provide readers a clear picture of the current status of this field,and to stimulate a broader interest in the applied mechanics community.     

基于虚拟变形法的车-桥耦合系统移动质量识别

利用双自由度质量-弹簧阻尼模型模拟移动车辆, 并基于虚拟变形(VDM)方法的结构快速重分 析思想, 提出一种车-桥耦合系统的移动质量快速识别的有效方法. 该方法以双自由度车体模 型的质量为变量, 通过最小化桥体结构实测响应和计算响应的平方距离来识别移动质量 (载荷), 避免了识别载荷时常遇到的病态问题, 对噪声鲁棒性强, 且需要传感器信息少. 每步优化 中, 利用在VDM方法基础上提出的移动动态影响矩阵概念, 无需时时重构车-桥耦合系统的时 变系统参数矩阵, 显著提高了计算效率. 利用数值框架梁模型, 通过比较不同车辆简化模型 对移动体质量及等效移动载荷的识别效果, 验证了该方法的可行性和有效性, 即使在5% 的噪声影响下, 利用一个传感器可以准确地识别多个移动体的质量.     

颗粒材料内部滑动变形局部化的离散元模拟

颗粒材料在加载过程中表现出非常复杂的变形性质.在微观尺度上,单个颗粒的运动、单个孔隙胞元内的变形都是非均匀的,但也不是完全随机、没有规律可循的,而是呈现一定结构性的分布,如微带、剪切带等.本文用基于孔隙胞元的离散元方法对颗粒体进行双轴加载数值试验,模拟了以滑动变形表征的变形局部化现象.数值结果发现,对应加载过程中的不同...     

岩石力学位移反演分析回顾及进展

回顾综述了岩石力学反演分析的研究进展，重点介绍了位移反分析法的分类、结果评价及研究特点，讨论了需进一步探讨的问题．     

采用共旋应变的三维热弹塑性有限变形有限元法

本文采用线性化共旋应变张量和增率型虚功原理，建立了有限变形热力耦合弹塑性有限元法。在该方法中，材料的流动应力取为应变总量、应变速率和温度的函数，推导了包含这种函数关系的本构矩阵。另外在温度场分析中，考虑了塑性功和摩擦功转化的热量。文后给出的算例表明该方法可以很好地模拟热加工过程。     

有限变形下一般流体时的热动力学模型

本文针对滑坡问题的本质, 提出了非不可压流体、非理想气体前提下, 在有限变形框架下牵涉到质量流动的热动力学模型, 得到了不同参数空间中的特征关系；并讨论了与其它相应理论间的区别。     

山西清徐地裂缝形变的InSAR监测分析

山西清徐地裂缝是近年汾渭盆地中活动最为剧烈的地裂缝之一,对耕地、道路和建筑物均造成了严重的破坏。为了监测该地裂缝的活动特征并推测其活动原因,采用差分合成孔径雷达干涉测量技术对该区域的地表形变进行了面状监测。由于受农田覆盖导致的严重时间去相干的影响,本文采用2007年时隔仅为70d的两景Envisat ASAR数据进行了解算,获取了该时间段清徐地区的整体地表形变,特别是清徐地裂缝两侧的形变梯度信息。结果显示: 清徐地裂缝南侧有一个长轴约为2km的地面沉降区域。进一步通过两条平行于地裂缝的剖线和多条垂直于地裂缝的剖线对该地裂缝形变的空间特征进行了分析,结果显示: 清徐地裂缝南侧为主要的形变区域,地裂缝最大的影响宽度达100m,而且地裂缝的不同地段的活动强度也不同, 70d的最大差异形变达5cm。从地裂缝与断裂的空间来看,该地裂缝位置受到交城断裂的控制,而推测近年地裂缝的异常活动则源于地裂缝南侧沉降中心的出现。     

GPS RTK技术用于滑坡动态实时变形监测的研究

为了研究GPS RTK技术用于滑坡动态变形监测的精度和可靠性,本文结合某类滑坡的大型物理模型试验,在滑坡体上布设了若干监测点,并用GPS RTK技术、全站仪三维测量技术和GPS单历元定位技术实时跟踪监测了该滑坡在自然状态下从稳定到产生破坏的全部过程。通过对监测数据的处理和分析,获得了RTK技术用于滑坡变形监测的可靠性和精度等技术参数,即在基准站和流动站同步观测到的卫星数在7颗以上且RTK系统的数据链能够正常工作的情况下,RTK测量的平面和高程精度就能分别控制在15mm和20mm以内。研究结果表明,RTK技术在一定条件下完全可用于滑坡灾害的动态实时变形监测。     

A MODEL OF TWO-PHASE EQUILIBRIUM FOR FORMATION OF KINK-BANDS IN ROCKS

Kink-bands in rocks have been widely observed in nature and imitated in the laboratory, and the mechanism of their formation has attracted much attention from various researchers for many years. In this paper, a two-phase equilibrium model is presented in which the kink-bands are considered as a high-strain phase and the other regions outside kink-bands as a low-strain phase and the discontinuity of the deformation gradient and stresses is permitted across the interface between those two phases. Based on the present model, we conduct the analysis for the rocks under plane strain compression by finding the minimum value of the compressive loading at which the governing equations have real, physically acceptable solutions. It is revealed that for the rocks with strain-softening behaviour, two-phase equilibrium solutions exist, and the critical value of the compressive loading, the inclination angle of the kink-band, and the stresses and strains inside and outside kink-bands can all be determined by the solution, which are in good agreement with experimental measurements and observations.     

MULTI-PULSE ORBITS AND CHAOTIC DYNAMICS OF A COMPOSITE LAMINATED RECTANGULAR PLATE

This paper presents an analysis on the nonlinear dynamics and multi-pulse chaotic motions of a simply-supported symmetric cross-ply composite laminated rectangular thin plate with the parametric and forcing excitations. Firstly, based on the Reddy’s third-order shear deformation plate theory and the model of the von Karman type geometric nonlinearity, the nonlinear governing partial difirential equations of motion for the composite laminated rectangular thin plate are derived by using the Hamilton’s principle. Then, using the second-order Galerkin discretization, the partial differential governing equations of motion are transformed to nonlinear ordinary differential equations. The case of the primary parametric resonance and 1:1 internal resonance is considered. Four-dimensional averaged equation is obtained by using the method of multiple scales. From the averaged equation obtained here, the theory of normal form is used to give the explicit expressions of normal form. Based on normal form, the energy phase method is utilized to analyze the global bifurcations and multi-pulse chaotic dynamics of the composite laminated rectangular thin plate. The theoretic results obtained above illustrate the existence of the chaos for the Smale horseshoe sense in a parametrical and forcing excited composite laminated thin plate. The chaotic motions of the composite laminated rectangular thin plate are also found by using numerical simulation, which also indicate that there exist different shapes of the multi-pulse chaotic motions for the composite laminated rectangular thin plate.