多波长线性回归－导数分光光度法测定对苯二酚、邻苯二酚和苯酚

本文将导数分光光度法与多波长线性回归法联用，测定了电有机合成产品中的对苯二酚、邻苯二酚和苯酚的含量。回收率在９５．０％～１００．１％之间。模拟合成样品分析结果的相对误差为０．１％～６．６％。方法简便。     

氟化富勒烯的研究进展

介绍了近几年来氟化富勒烯的合成、分离和一般性能.     

流动相组成对酒石酸衍生固定相手性拆分热力学函数的影响

流动相组成对酒石酸衍生固定相手性拆分热力学函数的影响;手性拆分;热力学函数;酒石酸;氨基酸衍生物;安息香     

三空缺杂多阴离子衍生物的合成与性质

合成了三空缺WellsDawson杂多阴离子的衍生物Na20[M2(X2W15O56)2].nH2O,其中X=P,As;M=Mn,Co,Cu,Zn,用红外光谱、可见光谱、极谱及元素分析对其进行了表征.用极谱法研究了这些化合物在水溶液中的稳定性和反应性,其极谱行为与单空缺阴离子2αP2W17O6110-相似,在4.2相似文献   

Pentastrontium Tris[tetraoxovanadate(V)] catena‐Monoxocuprate(I), Sr5(VO4)3(CuO) – An Apatite Derivative with Inserted Linear 1Ë[CuO]1– Chains

Sr₅(VO₄)₃(CuO) was prepared via solid state reactions from mixed powders of the metal oxides or carbonates in corundum crucibles in air (1173–1740 K). The compound is transparent and stable in air. The color changes with the preparation temperature from light gray (1173 K) to gray (1740 K). The crystal structure (space group P6₃/m, No. 176; Z = 2; a = 10.126 Å, c = 7.415 Å) is a derivative of the apatite Ca₅(PO₄)₃OH, and is characterized by isolated [VO₄]^3– anions (d(V–O) = 1.710 Å) and infinite linear ^1∞[CuO]^1– chains (d(Cu–O) = 1.854 Å) inserted in the channels parallel to the hexagonal axis. The compound prepared at 1740 K contains vacancies at the copper and oxygen positions of the linear chains (about 10% and 5%, respectively).     

Synthesis of polymethacrylate derivatives having sulfated maltoheptaose side chains with anti‐HIV activities

Anti‐HIV (human immunodeficiency virus) active polymethacrylates having pendant sulfated oligosaccharides were synthesized, and the relationship between structures and biological activities of the polymethacrylates was examined. Acetylated 1‐O‐methacryloyl maltoheptaoside (MA‐AcM7) was polymerized with AIBN as an initiator to give polymethacrylates having a pendant acetylated maltoheptaose in every repeating unit, poly(MA‐AcM7)s. After hydroxyl groups were recovered by deacetylation, the polymethacrylates having maltoheptaose units, poly(MA‐M7)s, were sulfated to give polymethacrylates having sulfated maltoheptaose side‐chains, poly(MA‐SM7)s, with degrees of sulfation of 1.1 to 2.7 (maximum, 3.0). These polymethacrylates including sulfated oligosaccharides exhibited low anti‐HIV activities represented by the 50% protecting concentration (EC₅₀) in the range of 15–62 μg/mL and low blood anticoagulant activities around 10 unit/mg (standard dextran sulfate, 22.7 unit/mg). The anti‐HIV activity increased with increasing degree of sulfation to reach EC₅₀ of 15–16 μg/mL. In addition, copolymerization of MA‐AcM7 with methyl methacrylate (MMA) and subsequent sulfation gave polymethacrylates consisting of various proportions of highly sulfated maltoheptaose and MMA units. It was revealed that the anti‐HIV activity increased with decreasing proportion of the sulfated oligosaccharide moiety and that a copolymethacrylate having 22 mol % of sulfated maltoheptaose units (DS = 3.0) had a high anti‐HIV activity in the EC₅₀ of 0.3 μg/mL. The blood anticoagulant activity increased slightly from 9 to 18 unit/mg with decreasing proportion of the sulfated maltoheptaose units. These results suggested that the biological activities were influenced strongly by the spatial distance between sulfated oligosaccharide substituents in the polymethacrylate main chain. Distinction and conformation of the oligosaccharide side chains also played an important role. © 1999 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 37: 789–800, 1999     

A Facile Synthesis of 3,4-Diamino-2,5-Diacylthieno[2,3-b]Thiophenes from Disodium(Dimercaptomethylene)Malononitrile and α-Halo Ketones

Various kinds of α-halo ketones readily reacted with disodium (dimercaptomethylene)malononitrile to give the corresponding 34-diamino-2,5-diacylthieno-[2,3-b]thiophenes in good to excellent yields. The reaction was successfully extended to the synthesis of a thienothiophene derivative having two sydnone rings by using the 4-(bromoacetyl)sydnone.     

甘草次酸衍生物的合成及其抗癌活性

设计合成了6种甘草次酸衍生物,用元素分析、波谱分析鉴定了它们的结构,并比较了它们的体内、体外抗癌活性,均表现出较好的活性,尤其是化合物Ⅰa,Ⅰb口服效果比盐酸氮芥还好,表现出甘草次酸对氮芥有明显的增效应用。     

脂溶性金属酞菁衍生物在介孔分子筛中的封装及其催化性质研究

采用浸法将钴酞菁衍生物组装进入介孔分子筛MCM－41中,通过XRD、UV－Vis紫外漫反射光谱,热分析、Raman光谱和N2吸附等方法对组装体进行了表征,并研究了共对硫醇氧化性能,结果表明,与体相钴酞菁衍生物相比,组装体具有优良的催化性能。     

Salicylaldehyde and dihydroisobenzofuran derivatives from the marine fungus Zopfiella marina

Two salicylaldehyde derivatives (1 and 2), a hydroxymethylphenol (3), five dihydroisobenzofuran (4–8) derivatives, and a 5-chloro-3-deoxyisoochracinic acid (9), together with a known 3-deoxyisoochracinic acid (10) were isolated from the marine fungus Zopfiella marina BCC 18240 (or NBRC 30420). The structures of these compounds were elucidated by extensive spectroscopic analysis. Compound 1 showed weak antituberculous activity against Mycobacterium tuberculosis H37Ra, and antibacterial activity against Bacillus cereus with MIC values of 25 and 12.5 μg/mL, respectively.