胂叶立德与具有对三氟甲基苯基及双吸电子基团烯烃的反应研究

鉮盐1以碳酸钾为碱分别与含对三氟甲基苯基及双吸电子基团的烯烃2或3反应, 高产率、高立体选择性地合成了含对三氟甲基苯基的顺-1,2-环丙烷衍生物4或顺-2,3-二氢呋喃衍生物5, 并对其产物结构进行了确证.     

A facile synthesis of novel dispiroheterocycles through solvent-free microwave-assisted [3+2] cycloaddition of azomethine ylides

A comparative study of the synthesis of novel dispiro pyrrolo/pyrrolizidino ring systems by the cycloaddition of azomethine ylides generated by a decarboxylative route from sarcosine/proline and isatin with the dipolarophile 9-arylidine-fluorene using four different methodologies is described. A solvent-free microwave-assisted approach gave products with the highest yields in a short time. Additionally, our solvent-free approach allowed the use of 4-N,N-dimethylaminobenzaldehyde, which failed to yield the desired cycloadducts under conventional approaches.     

A concise enantioselective synthesis of the fungal metabolite (+)-decarestrictine L

A stereoselective 10-step synthesis of the fungal metabolite (+)-decarestrictine L from commercially available ethyl (R)-3-hydroxybutyrate is described in which tandem oxonium ylide formation and rearrangement is used to construct the tetrahydropyranyl core of the natural product.     

Regioselective synthesis of 1-arylnaphthalenes from N-tosylaziridine derivatives

Regioselective synthesis of 1-arylnaphthalene derivatives was carried out from N-tosylaziridines, which was made from the reaction of N-tosylimines and cinnamyl bromides by using the sulfur ylide chemistry.     

昆虫性信息素的研究 Ⅱ.顺-11-十六碳烯醛的合成

顺-11-十六碳烯醛(10)是鳞翅目昆虫信息素的主要组份之一,它的合成在文献上已有一些报道。本文则报道从顺-5-癸烯醇-1(3)     

卤代羰基叶立德:“推-拉”稳定作用对四苯基环戊二烯酮与卡宾的脱氧反应的影响(英文)

研究了四苯基环戊二烯酮与三溴甲基苯基汞（二溴卡宾的前体化合物）的卡宾反应，发现该反应可给出比通常有立体障碍的酮要高得多的脱氧（以脱CO的形式）产率．本文从羰基叶立德中间体的“推-拉”稳定作用以及该中间体的构象和电子分布的角度出发，并结合产物分析对这一反常现象进行了讨论，发现在潜芳香结构的羰基化合物与二卤卡宾的反应中，有可能由于“推-拉”作用形成具有芳香结构的羰基是中间体，该中间体由于正负电荷及以较好的分散以及其接近0°／90°型的构象，有效地阻碍了分子间环加成和分子内电环化这两个竞争反应的进行，从而使脱氧途径成为该反应的主渠道．本项研究进一步揭示了一些尚未被人了解的反应规律，合理地解释了反应机理．     

Catalytic and Asymmetric Aziridination using Sulfur Ylides.

Abstract:

This paper describes a new method for the preparation of aziridines from imines and diazocompounds which requires catalytic amounts of metal salts and sulfides and operates under neutral conditions. Using enantiomerically pure sulfides, high enantioselectivity has been achieved in the aziridination process.     

TiO2-Mediated,One-Pot,Four-Component 1,3-Dipolar Cycloaddition Reaction: A Facile Synthesis of Dispiro-pyrrolidine Ring Systems

An expedient regioselective synthesis of dispiroindenoquinoxaline pyrrolidine derivatives mediated by TiO₂ in a one-pot, four-component 1,3-dipolar cycloaddition reaction is described.     

Insertion of O-H Bond of Rh（ Ⅱ）-methylene Carbene into Alcohols： A Stepwise Mechanism More Plausible than a Concerted Mechanism

IntroductionDirhodium(Ⅱ) complexes can catalyze the valua-ble dirhodium(Ⅱ) reactions ofα-diazo carbonyl com-pounds[1—7]. The generated Rh(Ⅱ) carbene interme-diates can subsequently undergo synthetically diversetransformations, including ylide formati