Quantile forecasting and data-driven inventory management under nonstationary demand

In this paper, a single-step framework for predicting quantiles of time series is presented. Subsequently, we propose that this technique can be adopted as a data-driven approach to determine stock levels in the environment of newsvendor problem and its multi-period extension. Theoretical and empirical findings suggest that our method is effective at modeling both weakly stationary and some nonstationary time series. On both simulated and real-world datasets, the proposed approach outperforms existing statistical methods and yields good newsvendor solutions.     

基于决策者信任水平和组合赋权的不完全偏好复杂大群体应急决策方法

针对属性权重完全未知且专家偏好出现残缺值的复杂大群体应急决策问题,提出了一种新的决策方法。首先,设计了一套基于决策者信任水平的残缺值填充机制,对缺失的偏好信息进行补充。然后,将各方案的大群体偏好信息进行聚类,基于方案信息熵和群体偏好冲突水平构建组合赋权方法,对属性权重进行测算,进而得到各个方案的综合评价值。最后对该方法进行了实例验证,验证结果表明本文提出的方法具有良好的可行性和有效性。     

基于直觉模糊二元语义交互式群决策的技术创新项目选择

为适应全球经济一体化的快速发展,企业应选择最优的技术创新项目,从而提升其竞争力。首先定义了直觉模糊二元语义,探讨了将其区间化的方法,建立了直觉模糊二元语义与区间模糊二元语义之间的联系。接着重新定义了直觉模糊二元语义的距离和相似度,给出了群决策的集结算子。通过集结决策者的意见和进行交互式决策,使得群体的决策意见达到满意的一致性水平。最后以技术创新项目选择为例说明了本文提出的方法。     

Red Wine Extract Inhibits VEGF Secretion and Its Signaling Pathway in Retinal ARPE-19 Cells to Potentially Disrupt AMD

Age-related macular degeneration (AMD) is a degenerative disease of the retina where the molecular mechanism involves the production of vascular endothelial growth factor (VEGF), a factor of poor prognosis of the progression of the disease. Previous studies have shown that resveratrol, a polyphenol of grapevines, can prevent VEGF secretion induced by stress from retinal cells. Considering the fundamental role played by VEGF in development and progression of AMD, we investigate the potential effect of red wine extract (RWE) on VEGF secretion and its signaling pathway in human retinal cells ARPE-19. To examine the effect of RWE in ARPE-19, a quantitative and qualitative analysis of the RWE was performed by HPLC MS/MS. We show for the first time that RWE decreased VEGF-A secretion from ARPE-19 cells and its protein expression in concentration-dependent manner. RWE-induced alteration in VEGF-A production is associated with a down of VEGF-receptor 2 (VEGF-R2) protein expression and its phosphorylated intracytoplasmic domain. Subsequently, the activation of kinase pathway is disturbing and RWE prevents the phosphorylation of MEK and ERK 1/2 in human retinal cells ARPE-19. Finally, this study sheds light on the interest that the use of polyphenolic cocktails could represent in a prevention strategy.     

保健酒中酞酸酯污染物的气相色谱-三重四极杆质谱法测定

建立了气相色谱—三重四极杆质谱(GC-MS/MS)联用法检测保健酒中的16种酞酸酯的方法.对保健酒中酞酸酯的前处理方法进行了考察和优化,确立了提取方式为沸水浴加热去除乙醇、提取溶剂为正己烷.采用时间选择反应扫描模式(T-SRM)定量.色谱柱为TG-5MS石英毛细管柱(30 m×0.25 mm×0.25μm),程序升温(初始柱温为60℃,保持1 min,以20℃/min升至220℃,保持1 min;以5℃/min升至280℃,保持4 min),不分流.结果表明16种酞酸酯在相应范围内线性关性良好(R~2均高于0.995),平均回收率在84.0%~112.8%,RSD均低于7%(n=6).采用方法对6批保健酒中酞酸酯进行测定,结果表明方法具有灵敏、简单快速、结果准确可靠等优点,GC-MS/MS联用法可满足保健酒中酞酸酯的定性分析和含量测定.     

Hybrid Electronic Tongue as a Tool for the Monitoring of Wine Fermentation and Storage Process

Hybrid electronic tongue based on potentiometric and voltammetric sensors was applied for the monitoring of wine production process. The sensor array formed by miniaturized ion‐selective electrodes and glassy carbon electrodes provided the analysis of the progress and correctness of wine fermentation and storage process, detection of the presence of disturbing factors and evaluation of the quality of final product. The efficiency of the proposed approach was compared with the monitoring of wine production carried out using standard reference methods. The results indicated that hybrid electronic tongue could be used as simple and reliable analytical tool dedicated to qualitative and quantitative assessment of wine production.     

Thermal analysis of Codex Huamantla and other Mexican papers

The application of thermal analysis and other techniques to determine the thermal and mechanical history of an object is extended to investigate the method of manufacturing of ancient papers. The Humboldt Fragment number six of the Codex Huamantla and other Mexican papers are analyzed by means of Differential Scanning Calorimetry (DSC) and Thermogravimetry-Mass Spectroscopy (TG-MS). The results reveal mechanical treatment or beating of the raw material and also indicate, that the two cultures exchanged knowledge about the paper making. The simplicity and speed of thermoanalytical methods make them a good choice to screen samples for composition and origin. With the addition of more elaborate techniques, such as X-ray analysis, IR spectroscopy, evolved gas analysis by mass spectrometry and microscopy, a definitive classification can be reached easily.Dedicated to Professor Bernhard Wunderlich on the occasion of his 65th birthdayPresented in part at the 4th Meeting of the Materials Research Society, Cancun May 16–20, 1994 Mexico.The authors wish to express their gratitude and appreciation to Senora Zita Basich, Museo Nacional de Antropologia, I.N.A.H., S.E.P. Cazada m. Gandhi, Mexico 5, D. F. and to Dr. Peter Masson, Ibero-Amerikanisches Institut Preussischer Kulturbesitz, Berlin, Potsdamer Strasse 37, Germany.     

人数与任务数不相等的指派问题

本提出人数与任务数不相等的指派问题应当视为一个多目标决策问题，首先要求指派给各人的任务数目两两之间相差不能超过1，其次要求所需总时间最少；并且给出了该问题的求解方法。     

有关Pareto解在DEA中的应用的探讨

对文[1]中有关DEA有效(C2R)的定理4,本文给出了在某种条件下的逆定理,以便简化DEA有效性(C2R)的判断.