椭圆形孔扩张弹性分析

圆孔扩张理论作为一种相对成熟的理论工具已经广泛运用于岩土工程中的各类问题,但是对于初始孔为椭圆孔的扩孔问题,圆孔扩张理论并不适用.基于保角变换的方法将原物理平面上初始椭圆孔洞的外部映射到像平面上的单位圆外部,将原物理平面上由于椭圆孔洞扩张所产生的位移边界条件转换到像平面上,利用平面复变弹性理论,得到初始椭圆形孔洞孔扩张的弹性解.将论文椭圆孔扩张的退化解与传统圆孔扩张的弹性解进行对比分析,验证椭圆孔扩张弹性解的正确性.续而,针对一算例详细分析了椭圆孔扩张的弹性力学特性.研究结果表明,椭圆孔的退化解与传统的圆孔扩张弹性解完全一致,椭圆孔在弹性扩张过程中长轴方向比短轴方向较难扩张,长轴方向需要的扩张压力比短轴方向的要大.此外,当扩张率a2/a1=0.11/0.1=1.1时,扩张的影响半径为10倍的孔径左右.     

掏槽参数对煤矿岩巷爆破效果的影响

为了提高掘进进尺,以川煤集团绿水洞矿掘进工程为背景,利用动力有限元程序LS-DYNA3D进行掏槽参数优化研究。结合井下现场实验,分析岩巷掏槽爆破不同参数动态应力、破碎范围的变化以及井下实际爆破效果。掏槽中心孔底向孔口平均有效应力峰值在有中心眼爆破较无中心眼爆破时增加了40%以上,中心眼爆破对槽腔底部的形成起主要作用。在其他条件相同的情况下单孔载荷从1.2 kg提高到1.8 kg,掏槽区中心眼底到孔口平均应力只增加20%,并且破碎范围的增加较少,实际进尺增加小于10%。现场掘进实验表明：在常规爆破载荷下,有中心眼比无中心眼爆破深度提高31%~65%,掏槽角小于78°时,随掏槽角度增加爆破进尺下降较平缓; 但掏槽角增至82°左右, 随掏槽角度增加爆破进尺下降明显。

     

The Role of Taraxacum mongolicum in a Puccinellia tenuiflora Community under Saline–Alkali Stress

Coexisting salt and alkaline stresses seriously threaten plant survival. Most studies have focused on halophytes; however, knowledge on how plants defend against saline–alkali stress is limited. This study investigated the role of Taraxacum mongolicum in a Puccinellia tenuiflora community under environmental saline–alkali stress to analyse the response of elements and metabolites in T. mongolicum, using P. tenuiflora as a control. The results show that the macroelements Ca and Mg are significantly accumulated in the aboveground parts (particularly in the stem) of T. mongolicum. Microelements B and Mo are also accumulated in T. mongolicum. Microelement B can adjust the transformation of sugars, and Mo contributes to the improvement in nitrogen metabolism. Furthermore, the metabolomic results demonstrate that T. mongolicum leads to decreased sugar accumulation and increased amounts of amino acids and organic acids to help plants resist saline–alkali stress. The resource allocation of carbon (sugar) and nitrogen (amino acids) results in the accumulation of only a few phenolic metabolites (i.e., petunidin, chlorogenic acid, and quercetin-3-O-rhamnoside) in T. mongolicum. These phenolic metabolites help to scavenge excess reactive oxygen species. Our study primarily helps in understanding the contribution of T. mongolicum in P. tenuiflora communities on coping with saline–alkali stress.     

K9玻璃在脉冲CO2激光作用下的热应力分析

根据已建立的理论模型,计算得到了K9玻璃受脉冲CO2激光辐照时产生的热应力分布,研究了热应力的时间特征,在分析样品尺寸对损伤结果影响的基础上,提出了K9玻璃抗激光损伤的最佳半径。结果表明：K9玻璃产生的热应力损伤主要由环向应力控制,热应力以热冲击波的形式在样品内传播,大小随时间变化而来回振荡,且激光脉冲结束后比激光作用时间内产生的热应力要大。这说明若样品在激光加热期间产生的热应力不足以造成材料破坏,则有可能会在其后的冷却过程中产生更大的热应力,材料将会在冷却过程中发生破裂。根据样品参数对损伤结果的影响,进一步验证了K9玻璃抗激光损伤最佳半径的通用性。     

10 T脉冲磁场的亥姆霍兹线圈热和力分析

亥姆霍兹线圈在产生数十T的准静态脉冲磁场的装置中得到广泛应用。以自行研制的一套用于磁压剪实验技术的脉冲磁场发生系统的亥姆霍兹线圈为研究对象,结合装置的电参数,利用有限元软件ANSYS对装置放电过程中线圈的热和力进行了仿真研究。研究结果表明,当装置在线圈中产生上升时间约1.34 ms、幅值14.37 kA的放电电流和10.7 T的磁场时,线圈中的最大温升约150 ℃,最大应力近0.5 GPa,铜导线中的最大应力约0.2 GPa,线圈导线变形位移小于0.05 mm。基于分析结果,在线圈制作时,选择绝缘层耐温超过200 ℃、抗拉强度0.5 GPa的铜导线作为线圈绕线,选择抗拉强度达5.8 GPa的柴龙纤维绕制在铜导线外层进行加固,并制作了相应结构的亥姆霍兹线圈对。利用该线圈对进行的放电实验测试结果表明,在满足设计指标的情况下,线圈对结实可靠,可重复使用。     

主应力的计算公式

在前人工作的基础上,运用一元三次方程的理论直接求解应力状态的特征方程,得到了实用的主应力计算公式.     

Acrylamide-Derived Ionome,Metabolic, and Cell Cycle Alterations Are Alleviated by Ascorbic Acid in the Fission Yeast

Acrylamide (AA), is a chemical with multiple industrial applications, however, it can be found in foods that are rich in carbohydrates. Due to its genotoxic and cytotoxic effects, AA has been classified as a potential carcinogen. With the use of spectrophotometry, ICP-OES, fluorescence spectroscopy, and microscopy cell growth, metabolic activity, apoptosis, ROS production, MDA formation, CAT and SOD activity, ionome balance, and chromosome segregation were determined in Schizosaccharomyces pombe. AA caused growth and metabolic activity retardation, enhanced ROS and MDA production, and modulated antioxidant enzyme activity. This led to damage to the cell homeostasis due to ionome balance disruption. Moreover, AA-induced oxidative stress caused alterations in the cell cycle regulation resulting in chromosome segregation errors, as 4.07% of cells displayed sister chromatid non-disjunction during mitosis. Ascorbic acid (AsA, Vitamin C), a strong natural antioxidant, was used to alleviate the negative impact of AA. Cell pre-treatment with AsA significantly improved AA impaired growth, and antioxidant capacity, and supported ionome balance maintenance mainly due to the promotion of calcium uptake. Chromosome missegregation was reduced to 1.79% (44% improvement) by AsA pre-incubation. Results of our multiapproach analyses suggest that AA-induced oxidative stress is the major cause of alteration to cell homeostasis and cell cycle regulation.     

Anthocyanins as Key Phytochemicals Acting for the Prevention of Metabolic Diseases: An Overview

Anthocyanins are water-soluble pigments present in fruits and vegetables, which render them an extensive range of colors. They have a wide distribution in the human diet, are innocuous, and, based on numerous studies, have supposed preventive and therapeutical benefits against chronic affections such as inflammatory, neurological, cardiovascular, digestive disorders, diabetes, and cancer, mostly due to their antioxidant action. Despite their great potential as pharmaceutical applications, they have a rather limited use because of their rather low stability to environmental variations. Their absorption was noticed to occur best in the stomach and small intestine, but the pH fluctuation of the digestive system impacts their rapid degradation. Urine excretion and tissue distribution also occur at low rates. The aim of this review is to highlight the chemical characteristics of anthocyanins and emphasize their weaknesses regarding bioavailability. It also targets to deliver an update on the recent advances in the involvement of anthocyanins in different pathologies with a focus on in vivo, in vitro, animal, and human clinical trials.     

Microwave Irradiation and Glutamic Acid-Assisted Phytotreatment of Tannery and Surgical Industrial Wastewater by Sorghum

We investigated how different doses of microwave irradiation (MR) affect seed germination in Sorghum, including the level of remediation against textile and surgical wastewater (WW) by modulating biochemical and morpho-physiological mechanisms under glutamic acid (GA) application. The experiment was conducted to determine the impact of foliar-applied GA on Sorghum under wastewater conditions. Plants were treated with or without microwave irradiation (30 s, 2.45 GHz), GA (5 and 10 mM), and wastewater (0, 25, 50, and 100). Growth and photosynthetic pigments were significantly decreased in plants only treated with various concentrations of WW. GA significantly improved the plant growth characteristics both in MR-treated and -untreated plants compared with respective controls. HMs stress increased electrolyte leakage (EL), hydrogen peroxide (H₂O₂), and malondialdehyde (MDA) content; however, the GA chelation significantly improved the antioxidant enzymes activities such as ascorbate oxidase (APX), superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) both in MR-treated and -untreated plants under WW stress compared with respective controls. The results suggested that the MR-treated plants accumulate higher levels of HMs under GA addition in comparison to the WW-only-treated and MR-untreated plants. The maximum increase in Cd accumulation was observed in the range of 14–629% in the roots, 15–2964% in the stems, and 26–4020% in the leaves; the accumulation of Cu was 18–2757% in the roots, 15–4506% in the stems, and 23–4605% in the leaves; and the accumulation of Pb was 13–4122% in the roots, 21–3588% in the stems, and 21–4990% in the leaves under 10 mM GA and MR-treated plants. These findings confirmed that MR-treated sorghum plants had a higher capacity for HMs uptake under GA and could be used as a potential candidate for wastewater treatment.     

Mulberry Ethanol Extract and Rutin Protect Alcohol-Damaged GES-1 Cells by Inhibiting the MAPK Pathway

Mulberry extract has been proven to have the effect of resisting alcohol damage, but its mechanism is still unclear. In this study, the composition of mulberry ethanol extract (MBE) was identified by LC-MS/MS and the main components of MBE were ascertained by measuring. Gastric mucosal epithelial (GES-1) cells were used to elucidate the mechanism of MBE and rutin (the central part of MBE) helped protect against alcohol damage. The results revealed that phenolics accounted for the majority of MBE, accounting for 308.6 mg/g gallic acid equivalents and 108 substances were identified, including 37 flavonoids and 50 non-flavonoids. The treatment of 400 μg/mL MBE and 320 μM rutin reduced early cell apoptosis and the content of intracellular reactive oxygen species, malondialdehyde and increased glutathione. The qPCR results indicated that the MBE inhibits the expression of genes in the mitogen-activated protein kinase (MAPK) pathway, including p38, JNK, ERK and caspase-3; rutin inhibits the expression of p38 and caspase-3. Overall, MBE was able to reduce the oxidative stress of GES-1 cells and regulated apoptosis-related genes of the MAPK pathway. This study provides information for developing anti-ethanol injury drugs or functional foods.