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21.
石金水 邓建军 章林文 李劲 夏连胜 陈思富 代志勇 李勤 李洪 赖青贵 禹海军 江孝国 杨安民 黄子平 李远 张篁 李欣 蒋薇 秦玲 刘小平 谌怡 廖树清 谢宇彤 陈德彪 何佳龙 章文卫 朱隽 丁亨松 戴光森 王远 王毅 马冰 王敏鸿 《强激光与粒子束》2016,28(01):010201
神龙二号加速器是一台以MHz猝发率猝发工作的三脉冲直线感应电子加速器。该加速器输出的三脉冲电子束,相邻两脉冲间最小时间间隔300 ns,而且可调,每个脉冲电子束的电子能量18~20 MeV、束流强度大于等于2 kA。当电子束与轫致辐射转换靶相互作用时,可产生三个强X光脉冲,X光斑点尺寸小于等于2 mm(FWHM),距靶1 m处照射量大于等于7.7410-2 C/kg (300 R)。该加速器涉及的主要关键技术包括三脉冲功率源设计、三脉冲强流高品质电子束源的产生、加速场建造、束流传输线设计、轫致辐射转换靶设计、测量与诊断技术等。 相似文献
22.
在针对脉冲电磁场肿瘤消融的应用场合,双极性脉冲比单极性脉冲效果更均匀,而要产生ns级前沿的双极性高压纳秒或亚微秒脉冲难度大,电磁干扰强,控制要求更高。设计了一台双极性全固态直线型变压器驱动源(SSLTD),双极性SSLTD由结构完全相同的LTD模块经过副边绕组反向串联构成,在负载上实现双极性窄脉冲。双极性SSLTD输出波形稳定的脉冲的关键在于磁芯复位,通过电阻负载实验,重点对比分析了复位电流的形式对复位效果的影响,以及采用直流复位时幅值、脉宽、正负脉冲时间间隔、单级模块中开关管并联数量、复位电流大小对双极性SSLTD输出的影响。实验结果表明,所设计的双极性SSLTD能够在500 Ω负载上稳定产生重频双极性纳秒脉冲,输出电压0~±5 kV可调,脉宽200~400 ns可调,正负脉冲时间间隔0~1 ms可调,上升沿和下降沿20~50 ns;反向串联的直流复位电路结构简单、复位效果好。该脉冲源使用模块化设计,结构紧凑,电气绝缘要求较低,可灵活输出双极性、正极性与负极性高压亚微秒脉冲。 相似文献
23.
Anton Rudenko Jean-Philippe Colombier Tatiana E. Itina Razvan Stoian 《Advanced Optical Materials》2021,9(20):2100973
Structuring below diffraction limit is key to developing new laser processing technologies as well as to understanding light-induced processes on mesoscopic scales, notably self-organization. Here, an advanced numerical perspective on the generation of embedded self-arranged sub-wavelength periodic patterns is developed, describing multipulse ultrafast laser interaction with bulk silica glass. Combining light and material dynamics, the approach couples self-consistently nonlinear propagation, electronic excitation, and fluid dynamics resulting in irreversible phase transitions and localized damage. With increasing the number of applied pulses, the modification changes from localized nanovoids and elongated random nanopatterns toward regular void nanogratings dominantly covering the spot of the focused laser beam. Driven by local and collective scattering events, the order imposed by electric field patterns is then amplified and stabilized by the material response. The model predicts the gradual evolution of the optical properties considering the complex interplay between material arrangement and the electromagnetic field distribution. It allows thus to define light transport optical functions optimizing losses and anisotropic effects. 相似文献
24.
Electroporation (EP) is one of the successful physical methods for intracellular drug delivery, which temporarily permeabilizes plasma membrane by exposing cells to electric pulses. Orientation of cells in electric field is important for electroporation and, consequently, for transport of molecules through permeabilized plasma membrane. Uptake of molecules after electroporation are the greatest at poles of cells facing electrodes and is often asymmetrical. However, asymmetry reported was inconsistent and inconclusive—in different reports it was either preferentially anodal or cathodal. We investigated the asymmetry of polar uptake of calcium ions after electroporation with electric pulses of different durations, as the orientation of elongated cells affects electroporation to a different extent when using electric pulses of different durations in the range of 100 ns to 100 µs. The results show that with 1, 10, and 100 µs pulses, the uptake of calcium ions is greater at the pole closer to the cathode than at the pole closer to the anode. With shorter 100 ns pulses, the asymmetry is not observed. A different extent of electroporation at different parts of elongated cells, such as muscle or cardiac cells, may have an impact on electroporation-based treatments such as drug delivery, pulse-field ablation, and gene electrotransfection. 相似文献
25.
Crouch R Boyer RD Johnson R Krishnamurthy K 《Magnetic resonance in chemistry : MRC》2004,42(3):301-307
Compensation of refocusing inefficiency in a gHMBC experiment by replacing the rectangular pi pulse with a pair of adiabatic pulses with synchronized inversion sweep (CRISIS) significantly improves the performance of the gHMBC experiment. The CRISIS-gHMBC experiment retains the pure absorptive shapes in F1 and hence results in better lineshape and higher resolution than the current versions of magnitude mode gHMBC spectra. When used as a broadband experiment, CRISIS-gHMBC, owing to better refocusing efficiency of the adiabatic pulse pairs, gives improved performance across the 13C spectral width. Moreover, it is shown that CRISIS-gHMBC is a robust and improved alternative and when used along with the IMPRESS (Improved Resolution using Symmetrically Shifted pulses) technique further increases the sensitivity and resolution without additional experimental time. The IMPRESS-CRISIS combination is demonstrated for broadband gHMBC and band-selective gHMBC experiments. The ICbs-gHMBC [IMPRESS-CRISIS-band-selective gHMBC] experiment is an attractive and better alternative to individual band-selective gHMBC. 相似文献
26.
第四讲 超强激光脉冲与等离子体相互作用中高能离子的产生 总被引:2,自引:0,他引:2
近几年来,由于高功率激光技术的不断发展,利用超强激光脉冲与等离子体相互作用产生高能离子束的研究得到了极大推动.实验和理论模拟均发现,在超强激光脉冲与等离子体相互作用过程中,可以产生高亮度、小尺寸、方向性好的高能质子束和高能重离子束.这种基于超强激光的高能离子源在先进离子束成像技术、惯性约束聚变混合“快点火”、新型台面离子加速器以及医疗等方面都有很诱人的应用前景.文章主要介绍了超强激光与固体靶相互作用中高能离子束(尤其是质子束)的加速机制、高能离子束特性、常用测量方法及其潜在应用,并对最新的研究进展进行了简单介绍. 相似文献
27.
28.
Finite pulse durations in diverse pulse schemes lead to the reduction of the magnitude of the magnetization vector due to T1 and T2 effects during the radio-frequency pulses. This paper presents an analysis of the steady state signal in the presence of relaxation effects during radio-frequency pulses in MRI spoiled gradient echo sequences. It is shown that minor attenuations of the magnetization vector can have dramatic consequences on the measured signal, and may thus entail a loss in SNR benefits at high static magnetic fields if a careful analysis is not performed. It is emphasized that it is the time-integrated magnetization vector trajectory that matters for these effects and not only the pulse duration. Some experimental results obtained on a phantom at 3 T verify this analysis. 相似文献
29.
锁模脉冲波长连续可调谐光纤激光器 总被引:1,自引:1,他引:1
利用在腔内加入可调谐光纤光栅滤波器使“8”字形腔掺Yb3+光纤激光器在锁模状态下实现波长连续可调谐.实验中,在保证锁模状态稳定的情况下,通过调节可调谐光纤光栅滤波器,使激光器输出锁模脉冲的中心波长在1047nm~1055nm范围内连续调谐,重复频率稳定维持在4.9MHz.在中心波长1053nm处,测得锁模脉冲输出平均功率为8.02mW,光谱带宽1nm,脉冲宽度为259.3ps.这种“8”字形腔被动锁模光纤激光器在锁模状态下对波长连续可调谐,并可长时间稳定工作. 相似文献
30.
Nuzillard JM 《Journal of magnetic resonance (San Diego, Calif. : 1997)》2007,187(2):193-198
The SERF experiment is a variant of the homonuclear J-resolved experiment, in which a single coupling constant is measured. It consists of a single chemical shift selective excitation that is followed by a biselective spin echo. Recent articles mention the existence of artefacts in SERF spectra that are supposedly related to pulse imperfections. This article presents a detailed study of the biselective refocusing pulses. It also reports a method for predicting the position and amplitude of the expected and unexpected 2D spectral peaks in SERF spectra. Artefacts can be partially eliminated by phase cycling or by the introduction of static field gradient pulses in the acquisition sequence. A procedure to obtain of pure absorption peaks in SERF spectra is proposed. 相似文献